Aliases for CTSL3P Gene

Aliases for CTSL3P Gene

  • Cathepsin L Family Member 3, Pseudogene 2 3 5
  • HCTSL-S 3 4
  • CTSL3 3 4
  • Putative Inactive Cathepsin L-Like Protein CTSL3P 4
  • Cathepsin L Family Member 3 2
  • Cathepsin L-Like Protein 3
  • Cathepsin L3 Pseudogene 4
  • EC 3.4.22 52

External Ids for CTSL3P Gene

Previous HGNC Symbols for CTSL3P Gene

  • CTSL3

Previous GeneCards Identifiers for CTSL3P Gene

  • GC09P090390

Summaries for CTSL3P Gene

GeneCards Summary for CTSL3P Gene

CTSL3P (Cathepsin L Family Member 3, Pseudogene) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include cysteine-type peptidase activity.

Additional gene information for CTSL3P Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CTSL3P Gene

Genomics for CTSL3P Gene

GeneHancer (GH) Regulatory Elements for CTSL3P Gene

Promoters and enhancers for CTSL3P Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09J087771 Enhancer 0.7 FANTOM5 Ensembl ENCODE 500.7 -1.5 -1452 1.6 RAD21 CHD2 CTCF CTSL3P piR-36393-530 RF00017-7681
GH09J087785 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.4 +14.3 14347 3.6 FOXA1 CTBP1 MYC NCOR1 FOXA2 NFIC TRIM24 CEBPB ZNF592 SPI1 CTSL ENSG00000214888 DAPK1 piR-54987-148 CTSL3P piR-31926-038 RF00017-7681
GH09J087776 Enhancer 0.7 Ensembl 0.7 +4.4 4448 1.4 KLF4 RBM25 NCOR1 NFIC ZNF592 BCOR TAL1 ZFP91 ADNP TCF12 ENSG00000237747 CTSL3P piR-54987-148 RF00017-7681
GH09J087766 Enhancer 0.9 Ensembl ENCODE 0.4 -5.4 -5394 1.1 ZNF217 KLF4 CUX1 CTBP1 GATAD2B ESRRA ZNF316 MBD2 NEUROD1 ELF1 CTSL3P piR-36393-530 RF00017-7681
GH09J087782 Enhancer 0.3 Ensembl 0.4 +11.0 11048 1.4 SPI1 E2F6 piR-54987-148 CTSL3P piR-31926-038 RF00017-7681
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CTSL3P on UCSC Golden Path with GeneCards custom track

Genomic Locations for CTSL3P Gene

Genomic Locations for CTSL3P Gene
chr9:87,772,453-87,786,884
(GRCh38/hg38)
Size:
14,432 bases
Orientation:
Plus strand
chr9:90,387,368-90,401,799
(GRCh37/hg19)
Size:
14,432 bases
Orientation:
Plus strand

Genomic View for CTSL3P Gene

Genes around CTSL3P on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTSL3P Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTSL3P Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTSL3P Gene

Proteins for CTSL3P Gene

  • Protein details for CTSL3P Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5NE16-CATL3_HUMAN
    Recommended name:
    Putative inactive cathepsin L-like protein CTSL3P
    Protein Accession:
    Q5NE16

    Protein attributes for CTSL3P Gene

    Size:
    218 amino acids
    Molecular mass:
    25059 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CTSL3P Gene

Selected DME Specific Peptides for CTSL3P Gene

Q5NE16:
  • VDWREKG
  • VTPVKDQ

Post-translational modifications for CTSL3P Gene

No Post-translational modifications

Domains & Families for CTSL3P Gene

Protein Domains for CTSL3P Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for CTSL3P Gene

GenScript: Design optimal peptide antigens:
  • HCTSL-s (CATL3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q5NE16

UniProtKB/Swiss-Prot:

CATL3_HUMAN :
  • Belongs to the peptidase C1 family.
Family:
  • Belongs to the peptidase C1 family.
genes like me logo Genes that share domains with CTSL3P: view

No data available for Gene Families for CTSL3P Gene

Function for CTSL3P Gene

Enzyme Numbers (IUBMB) for CTSL3P Gene

Phenotypes From GWAS Catalog for CTSL3P Gene

genes like me logo Genes that share phenotypes with CTSL3P: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTSL3P

No data available for Molecular function , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTSL3P Gene

Localization for CTSL3P Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CTSL3P Gene

Pathways & Interactions for CTSL3P Gene

PathCards logo

SuperPathways for CTSL3P Gene

No Data Available

Interacting Proteins for CTSL3P Gene

;

Gene Ontology (GO) - Biological Process for CTSL3P Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CTSL3P Gene

Drugs & Compounds for CTSL3P Gene

No Compound Related Data Available

Transcripts for CTSL3P Gene

mRNA/cDNA for CTSL3P Gene

1 REFSEQ mRNAs :
1 NCBI additional mRNA sequence :
2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTSL3P

Alternative Splicing Database (ASD) splice patterns (SP) for CTSL3P Gene

No ASD Table

Relevant External Links for CTSL3P Gene

GeneLoc Exon Structure for
CTSL3P

Expression for CTSL3P Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CTSL3P Gene

mRNA differential expression in normal tissues according to GTEx for CTSL3P Gene

This gene is overexpressed in Kidney - Cortex (x43.2) and Heart - Atrial Appendage (x6.6).

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CTSL3P

SOURCE GeneReport for Unigene cluster for CTSL3P Gene:

Hs.690450
genes like me logo Genes that share expression patterns with CTSL3P: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CTSL3P Gene

Orthologs for CTSL3P Gene

Evolution for CTSL3P Gene

ENSEMBL:
Gene Tree for CTSL3P (if available)
TreeFam:
Gene Tree for CTSL3P (if available)

No data available for Orthologs for CTSL3P Gene

Paralogs for CTSL3P Gene

(2) SIMAP similar genes for CTSL3P Gene using alignment to 1 proteins:

  • CATL3_HUMAN
genes like me logo Genes that share paralogs with CTSL3P: view

No data available for Paralogs for CTSL3P Gene

Variants for CTSL3P Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CTSL3P Gene

SNP ID Clinical significance and condition Chr 09 pos Variation AA Info Type
rs11141967 - p.Ser123Gly

Structural Variations from Database of Genomic Variants (DGV) for CTSL3P Gene

Variant ID Type Subtype PubMed ID
esv2759703 CNV loss 17122850
nsv8548 CNV gain 18304495
nsv972413 CNV duplication 23825009

Additional Variant Information for CTSL3P Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CTSL3P

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Additional dbSNP identifiers (rs#s) and Variation tolerance for CTSL3P Gene

Disorders for CTSL3P Gene

Additional Disease Information for CTSL3P

No disorders were found for CTSL3P Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTSL3P Gene

Publications for CTSL3P Gene

  1. CA/C1 peptidases of the malaria parasites Plasmodium falciparum and P. berghei and their mammalian hosts--a bioinformatical analysis. (PMID: 19663681) Xiao K … Dandekar T (Biological chemistry 2009) 2 3 54
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 54
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 54
  5. Characterization of a cDNA encoding a cathepsin L-like protein of Rhodnius prolixus. (PMID: 11881815) Lopez-Ordoñez T … Hernández-Hernández FD (Insect molecular biology 2001) 23 54

Products for CTSL3P Gene

Sources for CTSL3P Gene