Aliases for CTRC Gene
External Ids for CTRC Gene
Previous GeneCards Identifiers for CTRC Gene
This gene encodes a member of the peptidase S1 family. The encoded protein is a serum calcium-decreasing factor that has chymotrypsin-like protease activity. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTRC Gene
CTRC (Chymotrypsin C) is a Protein Coding gene. Diseases associated with CTRC include Pancreatitis, Hereditary and Tropical Calcific Pancreatitis. Among its related pathways are Metabolism of water-soluble vitamins and cofactors and Metabolism. Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase activity and peptidase activity. An important paralog of this gene is CTRB2.
UniProtKB/Swiss-Prot Summary for CTRC Gene
Regulates activation and degradation of trypsinogens and procarboxypeptidases by targeting specific cleavage sites within their zymogen precursors. Has chymotrypsin-type protease activity and hypocalcemic activity.