Aliases for CTNNBIP1 Gene
External Ids for CTNNBIP1 Gene
Previous GeneCards Identifiers for CTNNBIP1 Gene
The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CTNNBIP1 Gene
CTNNBIP1 (Catenin Beta Interacting Protein 1) is a Protein Coding gene. Diseases associated with CTNNBIP1 include Keratocystic Odontogenic Tumor and Anterior Segment Dysgenesis 5. Among its related pathways are Regulation of Wnt-mediated beta catenin signaling and target gene transcription and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include beta-catenin binding and armadillo repeat domain binding. An important paralog of this gene is LZIC.
UniProtKB/Swiss-Prot Summary for CTNNBIP1 Gene
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.