Aliases for CTNNA3 Gene
Aliases for CTNNA3 Gene
External Ids for CTNNA3 Gene
- HGNC: 2511
- Entrez Gene: 29119
- Ensembl: ENSG00000183230
- OMIM: 607667
- UniProtKB: Q9UI47
Previous GeneCards Identifiers for CTNNA3 Gene
- GC00U990693
- GC10M067024
- GC10M067349
- GC10M067679
- GC10M061677
Summaries for CTNNA3 Gene
-
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
GeneCards Summary for CTNNA3 Gene
CTNNA3 (Catenin Alpha 3) is a Protein Coding gene. Diseases associated with CTNNA3 include Arrhythmogenic Right Ventricular Dysplasia, Familial, 13 and Arrhythmogenic Right Ventricular Cardiomyopathy. Among its related pathways are PAK Pathway and Gastric cancer. Gene Ontology (GO) annotations related to this gene include structural molecule activity and beta-catenin binding. An important paralog of this gene is CTNNA2.
UniProtKB/Swiss-Prot for CTNNA3 Gene
-
May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Additional gene information for CTNNA3 Gene
- Monarch Initiative
- Search for CTNNA3 at DataMed
- Search for CTNNA3 at HumanCyc
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTNNA3 Gene
Genomics for CTNNA3 Gene
GeneHancer (GH) Regulatory Elements for CTNNA3 Gene
Promoters and enhancers for CTNNA3 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH10I067763 | Enhancer | 1.3 | Ensembl ENCODE | 558.7 | -0.7 | -745 | 2.6 | HDGF ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 E2F8 ZNF207 ZNF143 | CTNNA3 TRS-TGA1-1 CCAR1 HNRNPH3 HERC4 SIRT1 RUFY2 RPL26P27 TET1 | |
| GH10I067667 | Promoter | 0.8 | EPDnew | 550.2 | +98.0 | 98020 | 0.1 | ZNF148 ZNF335 PKNOX1 POLR2A DPF2 | CTNNA3 AKR1B10P1 PIR34883 | |
| GH10I067696 | Promoter | 0.6 | EPDnew | 550.2 | +67.4 | 67438 | 0.1 | ATF7 | CTNNA3 AKR1B10P1 PIR34883 | |
| GH10I067761 | Enhancer | 0.4 | Ensembl | 550.8 | +1.7 | 1655 | 0.4 | ZNF316 ZBTB33 | CTNNA3 AKR1B10P1 | |
| GH10I067762 | Enhancer | 0.2 | Ensembl | 550.8 | +0.7 | 709 | 0.2 | CTNNA3 TRS-TGA1-1 AKR1B10P1 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CTNNA3 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for CTNNA3 Gene
Genomic Locations for CTNNA3 Gene
- chr10:65,912,518-67,763,610
- (GRCh38/hg38)
- Size:
- 1,851,093 bases
- Orientation:
- Minus strand
- chr10:67,672,276-69,455,949
- (GRCh37/hg19)
Genomic View for CTNNA3 Gene
Genes around CTNNA3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 10q21.3 by Ensembl
- 10q21.3 by Entrez Gene
- 10q21.3 by HGNC
CTNNA3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CTNNA3 Gene
Proteins for CTNNA3 Gene
-
Protein details for CTNNA3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9UI47-CTNA3_HUMAN
- Recommended name:
- Catenin alpha-3
- Protein Accession:
- Q9UI47
- Q5VSR2
- Q6P056
Protein attributes for CTNNA3 Gene
- Size:
- 895 amino acids
- Molecular mass:
- 99809 Da
- Quaternary structure:
-
- Interacts with CTNNB1.
Protein Expression for CTNNA3 Gene
Post-translational modifications for CTNNA3 Gene
No Post-translational modifications
Other Protein References for CTNNA3 Gene
Antibody Products
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-
Abcam antibodies for CTNNA3
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- GeneTex CTNNA3 antibody for CTNNA3
-
Santa Cruz Biotechnology (SCBT) Antibodies for CTNNA3
- Sino Biological Antibodies for CTNNA3
Protein Products
-
OriGene Purified Proteins for CTNNA3
- Search Origene for MassSpec and Protein Over-expression Lysates for CTNNA3
- Origene Custom Protein Services for CTNNA3
- antibodies-online: Search results for 4 available CTNNA3 Proteins ranked by validation data
- Compare Top CTNNA3 Proteins
-
Quality Products:
- Search GeneTex for Proteins for CTNNA3
-
Abcam proteins for CTNNA3
Assay Products
No data available for DME Specific Peptides for CTNNA3 Gene
Domains & Families for CTNNA3 Gene
Gene Families for CTNNA3 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted intracellular proteins
Protein Domains for CTNNA3 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CTNNA3 Gene
Graphical View of Domain Structure for InterPro Entry
Q9UI47- Family:
-
- Belongs to the vinculin/alpha-catenin family.
Function for CTNNA3 Gene
Molecular function for CTNNA3 Gene
- UniProtKB/Swiss-Prot Function:
- May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Phenotypes From GWAS Catalog for CTNNA3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 11590244 |
| GO:0008013 | beta-catenin binding | IPI | 23136403 |
| GO:0045296 | cadherin binding | IEA,TAS | 11590244 |
| GO:0051015 | actin filament binding | IEA | -- |
Phenotypes for CTNNA3 Gene
- MGI mutant phenotypes for CTNNA3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CTNNA3:
Animal Models for CTNNA3 Gene
- MGI Knock Outs for CTNNA3:
-
- Ctnna3 tm1.1Fvr
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CTNNA3
-
-
ViGene Biosciences lentiviral particle packaged cDNA for CTNNA3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CTNNA3 gene
- Search ViGene Biosciences for CTNNA3
CRISPR Products
-
OriGene CRISPR knockouts for CTNNA3
- genomics-online: gRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- Applied Biological Materials CRISPR for CTNNA3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CTNNA3
- GenScript: Design CRISPR guide RNA sequences for CTNNA3
miRNA for CTNNA3 Gene
- miRTarBase miRNAs that target CTNNA3
-
- hsa-mir-182-5p (MIRT442967)
- hsa-mir-5704 (MIRT442968)
- hsa-mir-4470 (MIRT442969)
- hsa-mir-3065-5p (MIRT442970)
- hsa-mir-3613-3p (MIRT442971)
- hsa-mir-1295b-3p (MIRT442972)
- hsa-mir-15a-3p (MIRT442973)
- hsa-mir-4717-5p (MIRT442974)
- hsa-mir-6826-3p (MIRT643565)
- hsa-mir-6891-3p (MIRT643566)
- hsa-mir-6072 (MIRT643567)
- hsa-mir-6795-3p (MIRT643568)
- hsa-mir-6887-3p (MIRT643569)
- hsa-mir-548ay-3p (MIRT643570)
- hsa-mir-548at-3p (MIRT643571)
- hsa-mir-548as-3p (MIRT643572)
- hsa-mir-548t-3p (MIRT643573)
- hsa-mir-548ap-3p (MIRT643574)
- hsa-mir-548aa (MIRT643575)
- hsa-mir-548x-3p (MIRT643576)
- hsa-mir-548j-3p (MIRT643577)
- hsa-mir-548aq-3p (MIRT643578)
- hsa-mir-548am-3p (MIRT643579)
- hsa-mir-548aj-3p (MIRT643580)
- hsa-mir-548ah-3p (MIRT643581)
- hsa-mir-548ae-3p (MIRT643582)
miRNA Products
- Search ViGene Biosciences for CTNNA3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CTNNA3
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- genomics-online: shRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
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ViGene Biosciences ready-to-package AAV shRNAs for CTNNA3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
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-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CTNNA3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CTNNA3
-
ViGene Biosciences adenoviral particle packaged cDNA for CTNNA3 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CTNNA3 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for CTNNA3 gene
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for CTNNA3 Gene
Localization for CTNNA3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CTNNA3 Gene
- Cytoplasm, cytoskeleton. Note=Localizes to intercalated disks of cardiomyocytes and in peritubular myoid cells of testis, and colocalizes with CTNNA1 and CTNNA2. {ECO:0000269 PubMed:11590244}.
| Compartment | Confidence |
|---|---|
| cytoskeleton | 4 |
| plasma membrane | 2 |
| nucleus | 2 |
| cytosol | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005856 | cytoskeleton | IEA | -- |
| GO:0005912 | adherens junction | IEA | -- |
| GO:0005916 | fascia adherens | IDA,IEA | 11590244 |
| GO:0030027 | lamellipodium | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CTNNA3 Gene
Pathways & Interactions for CTNNA3 Gene
Pathways by source for CTNNA3 Gene
1 BioSystems pathway for CTNNA3 Gene
8 KEGG pathways for CTNNA3 Gene
3 GeneGo (Thomson Reuters) pathways for CTNNA3 Gene
4 R&D Systems pathways for CTNNA3 Gene
- Blood-Brain Barrier and Immune Cell Transmigration: CCL2/MCP-1 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: ICAM-1/CD54 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: VEGF Signaling Pathways
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007155 | cell adhesion | IEA | -- |
| GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication | IMP | 23136403 |
| GO:0086091 | regulation of heart rate by cardiac conduction | IMP | 23136403 |
| GO:0098609 | cell-cell adhesion | IPI,IEA | 11590244 |
| GO:0098911 | regulation of ventricular cardiac muscle cell action potential | IMP | 23136403 |
No data available for SIGNOR curated interactions for CTNNA3 Gene
Drugs & Compounds for CTNNA3 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| antidepressants | Pharma | 0 |
Transcripts for CTNNA3 Gene
mRNA/cDNA for CTNNA3 Gene
- (11) REFSEQ mRNAs :
- (8) Additional mRNA sequences :
- (18) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CTNNA3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CTNNA3
- genomics-online: gRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- Applied Biological Materials CRISPR for CTNNA3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CTNNA3
- GenScript: Design CRISPR guide RNA sequences for CTNNA3
miRNA Products
- Search ViGene Biosciences for CTNNA3
Inhibitory RNA Products
- Origene RNAi, sirna, and shrna products in human, mouse, rat for CTNNA3
- Browse OriGene Inhibitory RNA Products For CTNNA3
- genomics-online: shRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for CTNNA3 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for CTNNA3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CTNNA3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for CTNNA3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CTNNA3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
mRNA differential expression in normal tissues according to GTEx for CTNNA3 Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x8.9) and Heart - Left Ventricle (x6.5).
This gene is overexpressed in Heart (25.7), Spinal cord (22.4), and Fetal heart (18.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CTNNA3 Gene
NURSA nuclear receptor signaling pathways regulating expression of CTNNA3 Gene:
CTNNA3SOURCE GeneReport for Unigene cluster for CTNNA3 Gene:
Hs.660362mRNA Expression by UniProt/SwissProt for CTNNA3 Gene:
Q9UI47-CTNA3_HUMAN
Tissue specificity:
Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle.
Evidence on tissue expression from TISSUES for CTNNA3 Gene
- Nervous system(4.3)
- Liver(4.1)
- Heart(3.4)
- Lung(2.5)
- Pancreas(2.5)
- Eye(2.3)
- Muscle(2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for CTNNA3 Gene
Germ Layers:
- mesoderm
Systems:
- cardiovascular
Regions:
Head and neck:
- ear
Thorax:
- heart
- heart valve
General:
- blood
- blood vessel
Primer Products
-
OriGene qPCR primer pairs for CTNNA3
- genomics-online: primer clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
No data available for Protein tissue co-expression partners for CTNNA3 Gene
Orthologs for CTNNA3 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CTNNA3 33 34 |
|
||
| dog (Canis familiaris) |
Mammalia | CTNNA3 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | CTNNA3 33 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| -- 34 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Ctnna3 33 16 34 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Ctnna3 33 |
|
||
| chicken (Gallus gallus) |
Aves | CTNNA3 33 34 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 34 |
|
ManyToMany | |
| -- 34 |
|
ManyToMany |
- Species where no ortholog for CTNNA3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for CTNNA3 Gene
(2) SIMAP similar genes for CTNNA3 Gene using alignment to 8 proteins:
Variants for CTNNA3 Gene
| SNP ID | Clin | Chr 10 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1060502222 | uncertain-significance, Arrhythmogenic right ventricular dysplasia, familial, 13 | 66,103,240(-) | C/T | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1060502223 | uncertain-significance, Arrhythmogenic right ventricular dysplasia, familial, 13 | 66,103,185(-) | C/T | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs1060504519 | likely-benign, Arrhythmogenic right ventricular dysplasia, familial, 13 | 66,379,348(-) | G/A | coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant | |
| rs10997034 | benign, Arrhythmogenic right ventricular dysplasia, familial, 13 | 66,280,482(-) | G/T | coding_sequence_variant, genic_downstream_transcript_variant, synonymous_variant | |
| rs111880127 | benign, Arrhythmogenic right ventricular dysplasia, familial, 13 | 67,539,533(-) | A/G | coding_sequence_variant, genic_upstream_transcript_variant, synonymous_variant |
Residual Variation Intolerance Score:
39.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.26;
90.57% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CTNNA3 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CTNNA3 Gene
Disorders for CTNNA3 Gene
(8) MalaCards diseases for CTNNA3 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| arrhythmogenic right ventricular dysplasia, familial, 13 |
|
|
| arrhythmogenic right ventricular cardiomyopathy |
|
|
| familial isolated arrhythmogenic ventricular dysplasia, right dominant form |
|
|
| familial isolated arrhythmogenic ventricular dysplasia, biventricular form |
|
|
| familial isolated arrhythmogenic ventricular dysplasia, left dominant form |
|
|
Search CTNNA3 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
CTNA3_HUMAN- Arrhythmogenic right ventricular dysplasia, familial, 13 (ARVD13) [MIM:615616]: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias. {ECO:0000269 PubMed:23136403}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for CTNNA3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for Genatlas for CTNNA3 Gene
Publications for CTNNA3 Gene
- Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy. (PMID: 12596047) Janssens B … Towbin JA (Human genetics 2003) 2 3 4 22 58
- Alpha-T-catenin (CTNNA3) gene was identified as a risk variant for toluene diisocyanate-induced asthma by genome-wide association analysis. (PMID: 19187332) Kim SH … Park HS (Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009) 3 22 44 58
- An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3. (PMID: 19105203) Edwards TL … Ritchie MD (American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009) 3 22 44 58
- Is alpha-T catenin (VR22) an Alzheimer's disease risk gene? (PMID: 17209133) Bertram L … Tanzi RE (Journal of medical genetics 2007) 3 22 44 58
- Interaction between the alpha-T catenin gene (VR22) and APOE in Alzheimer's disease. (PMID: 16199552) Martin ER … Pericak-Vance MA (Journal of medical genetics 2005) 3 22 44 58
Products for CTNNA3 Gene
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- Browse Antibodies at Cloud-Clone Corp.
- Browse Proteins at Cloud-Clone Corp.
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- Cloud-Clone Corp. disease models service
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- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for CTNNA3
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for CTNNA3
- VectorBuilder custom plasmid, inducible vectors for CTNNA3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CTNNA3
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 67 available CTNNA3 Antibodies ranked by validation data
- Compare Top CTNNA3 Antibodies
- antibodies-online: Search results for available CTNNA3 related products ranked by validation data
- antibodies-online: Search results for 4 available CTNNA3 Proteins ranked by validation data
- Compare Top CTNNA3 Proteins
- Quality Products:
- GeneTex CTNNA3 antibody for CTNNA3
- Search GeneTex for Proteins for CTNNA3
- ViGene Biosciences adenoviral particle packaged cDNA for CTNNA3 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CTNNA3 gene
- ViGene Biosciences ready-to-package AAV shRNAs for CTNNA3 gene
- Search ViGene Biosciences for CTNNA3
- Santa Cruz Biotechnology (SCBT) Antibodies for CTNNA3
- Search Santa Cruz Biotechnology (SCBT) for CTNNA3 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CTNNA3
- Horizon Cell Lines for CTNNA3
- genomics-online: cdna clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- orf clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- genomics-online: gRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- genomics-online: primer clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
- genomics-online: shRNA clones - Search results for 86 available CTNNA3 gene related products
- Overview of 86 available CTNNA3 gene related products
Sources for CTNNA3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew