Aliases for CTDNEP1 Gene
External Ids for CTDNEP1 Gene
Previous HGNC Symbols for CTDNEP1 Gene
Previous GeneCards Identifiers for CTDNEP1 Gene
GeneCards Summary for CTDNEP1 Gene
CTDNEP1 (CTD Nuclear Envelope Phosphatase 1) is a Protein Coding gene. Among its related pathways are Mitotic Prophase and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include phosphatase activity and protein serine/threonine phosphatase activity. An important paralog of this gene is CTDSPL.
UniProtKB/Swiss-Prot for CTDNEP1 Gene
Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling.