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Aliases for CTAGE8 Gene

Aliases for CTAGE8 Gene

  • CTAGE Family Member 8 2 3 3 5
  • Protein CTAGE-8 3 4
  • Cutaneous T-Cell Lymphoma-Associated Antigen 8 3
  • CTAGE Family, Member 4 Pseudogene 3
  • CTAGE Family, Member 8 2

External Ids for CTAGE8 Gene

Previous GeneCards Identifiers for CTAGE8 Gene

  • GC07U902615
  • GC07M143963

Summaries for CTAGE8 Gene

GeneCards Summary for CTAGE8 Gene

CTAGE8 (CTAGE Family Member 8) is a Protein Coding gene. An important paralog of this gene is CTAGE4.

Additional gene information for CTAGE8 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CTAGE8 Gene

Genomics for CTAGE8 Gene

GeneHancer (GH) Regulatory Elements for CTAGE8 Gene

Promoters and enhancers for CTAGE8 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J144833 Promoter/Enhancer 2.1 EPDnew Ensembl ENCODE 11.7 -565.7 -565746 3.2 DMAP1 YY1 ZNF213 ZNF143 SP3 NFYC ZNF610 GLIS1 NBN KDM1A TPK1 CTAGE8 LOC154761 OR2A1 GC07M144690
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CTAGE8 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CTAGE8 Gene

Genomic Locations for CTAGE8 Gene
chr7:144,266,674-144,269,784
(GRCh38/hg38)
Size:
3,111 bases
Orientation:
Minus strand
chr7:143,963,794-143,966,381
(GRCh37/hg19)

Genomic View for CTAGE8 Gene

Genes around CTAGE8 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTAGE8 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTAGE8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAGE8 Gene

Proteins for CTAGE8 Gene

  • Protein details for CTAGE8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG41-CTGE8_HUMAN
    Recommended name:
    cTAGE family member 8
    Protein Accession:
    P0CG41

    Protein attributes for CTAGE8 Gene

    Size:
    777 amino acids
    Molecular mass:
    88077 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CTAGE8 Gene

Post-translational modifications for CTAGE8 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAGE8 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTAGE8 Gene

Domains & Families for CTAGE8 Gene

Gene Families for CTAGE8 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CTAGE8 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CTAGE8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CG41

UniProtKB/Swiss-Prot:

CTGE8_HUMAN :
  • Belongs to the cTAGE family.
Family:
  • Belongs to the cTAGE family.
genes like me logo Genes that share domains with CTAGE8: view

Function for CTAGE8 Gene

Gene Ontology (GO) - Molecular Function for CTAGE8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042954 lipoprotein transporter activity IBA --
genes like me logo Genes that share ontologies with CTAGE8: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTAGE8

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTAGE8 Gene

Localization for CTAGE8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAGE8 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CTAGE8 gene
Compartment Confidence
nucleus 2

Gene Ontology (GO) - Cellular Components for CTAGE8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005789 endoplasmic reticulum membrane IBA --
GO:0016021 integral component of membrane IEA --
GO:0070971 endoplasmic reticulum exit site IBA --
genes like me logo Genes that share ontologies with CTAGE8: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CTAGE8 Gene

Pathways & Interactions for CTAGE8 Gene

SuperPathways for CTAGE8 Gene

No Data Available

Interacting Proteins for CTAGE8 Gene

Gene Ontology (GO) - Biological Process for CTAGE8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006888 ER to Golgi vesicle-mediated transport IBA --
GO:0009306 protein secretion IBA --
GO:0035459 cargo loading into vesicle IBA --
genes like me logo Genes that share ontologies with CTAGE8: view

No data available for Pathways by source and SIGNOR curated interactions for CTAGE8 Gene

Drugs & Compounds for CTAGE8 Gene

No Compound Related Data Available

Transcripts for CTAGE8 Gene

mRNA/cDNA for CTAGE8 Gene

(1) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CTAGE8 Gene

CTAGE family, member 8:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTAGE8

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CTAGE8 Gene

No ASD Table

Relevant External Links for CTAGE8 Gene

GeneLoc Exon Structure for
CTAGE8
ECgene alternative splicing isoforms for
CTAGE8

Expression for CTAGE8 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CTAGE8 Gene

mRNA differential expression in normal tissues according to GTEx for CTAGE8 Gene

This gene is overexpressed in Testis (x6.7), Thyroid (x4.5), Skin - Sun Exposed (Lower leg) (x4.3), and Skin - Not Sun Exposed (Suprapubic) (x4.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CTAGE8 Gene



Protein tissue co-expression partners for CTAGE8 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CTAGE8 Gene:

CTAGE8

SOURCE GeneReport for Unigene cluster for CTAGE8 Gene:

Hs.661442

Evidence on tissue expression from TISSUES for CTAGE8 Gene

  • Liver(2.2)
genes like me logo Genes that share expression patterns with CTAGE8: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CTAGE8 Gene

Orthologs for CTAGE8 Gene

This gene was present in the common ancestor of animals.

Orthologs for CTAGE8 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC470576 33
  • 94.7 (n)
cow
(Bos Taurus)
Mammalia -- 34
  • 72 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Ctage5 34
  • 66 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 45 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 34 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 30 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 31 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ctage5 34
  • 35 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Tango1 34
  • 9 (a)
OneToMany
Species where no ortholog for CTAGE8 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CTAGE8 Gene

ENSEMBL:
Gene Tree for CTAGE8 (if available)
TreeFam:
Gene Tree for CTAGE8 (if available)

Paralogs for CTAGE8 Gene

Paralogs for CTAGE8 Gene

(7) SIMAP similar genes for CTAGE8 Gene using alignment to 1 proteins:

  • CTGE8_HUMAN

Pseudogenes.org Pseudogenes for CTAGE8 Gene

genes like me logo Genes that share paralogs with CTAGE8: view

Variants for CTAGE8 Gene

Sequence variations from dbSNP and Humsavar for CTAGE8 Gene

SNP ID Clin Chr 07 pos Variation AA Info Type
rs1006678756 -- 144,271,363(-) G/A upstream_transcript_variant
rs1007037239 -- 144,270,471(-) T/C upstream_transcript_variant
rs1011375967 -- 144,270,623(-) T/C upstream_transcript_variant
rs1011428469 -- 144,271,461(-) G/C upstream_transcript_variant
rs1018140529 -- 144,270,515(-) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CTAGE8 Gene

Variant ID Type Subtype PubMed ID
dgv11668n54 CNV gain 21841781
dgv11669n54 CNV loss 21841781
dgv152e203 CNV gain+loss 21179565
dgv24n31 CNV gain 19718026
dgv253n111 CNV duplication 26073780
dgv254n111 CNV duplication 26073780
dgv255n111 CNV deletion 26073780
dgv3965e59 CNV duplication 20981092
dgv3972e59 CNV duplication 20981092
dgv6725n100 CNV gain 25217958
dgv6726n100 CNV gain 25217958
dgv6727n100 CNV loss 25217958
dgv6728n100 CNV gain+loss 25217958
dgv6729n100 CNV gain 25217958
dgv6730n100 CNV loss 25217958
dgv6731n100 CNV gain+loss 25217958
dgv6732n100 CNV gain+loss 25217958
dgv6733n100 CNV gain+loss 25217958
dgv6734n100 CNV gain+loss 25217958
dgv6735n100 CNV gain 25217958
dgv6736n100 CNV gain 25217958
dgv6737n100 CNV gain 25217958
dgv6738n100 CNV gain+loss 25217958
dgv6739n100 CNV gain+loss 25217958
dgv6740n100 CNV loss 25217958
dgv6741n100 CNV loss 25217958
dgv6742n100 CNV loss 25217958
dgv6743n100 CNV gain+loss 25217958
dgv6744n100 CNV loss 25217958
esv1003295 OTHER inversion 20482838
esv1682998 OTHER inversion 17803354
esv24292 CNV gain+loss 19812545
esv2759570 CNV gain+loss 17122850
esv3369041 CNV duplication 20981092
esv3379639 CNV duplication 20981092
esv3380478 CNV duplication 20981092
esv3432947 CNV duplication 20981092
esv3584873 CNV loss 24956385
esv3891225 CNV gain 25118596
esv8347 OTHER inversion 19470904
nsv1016831 CNV gain 25217958
nsv1032320 CNV gain 25217958
nsv1119234 CNV duplication 24896259
nsv1119235 CNV duplication 24896259
nsv1133019 OTHER inversion 24896259
nsv1141559 CNV duplication 24896259
nsv1148453 CNV duplication 26484159
nsv1153905 CNV duplication 26484159
nsv428188 CNV gain+loss 18775914
nsv433394 CNV gain 18776910
nsv469769 CNV gain+loss 16826518
nsv471646 CNV gain+loss 15918152
nsv508489 CNV deletion 20534489
nsv510970 OTHER inversion 20534489
nsv515041 CNV gain 21397061
nsv608699 CNV gain 21841781
nsv608829 CNV loss 21841781
nsv608831 CNV loss 21841781
nsv608840 CNV loss 21841781
nsv608845 CNV loss 21841781
nsv7411 OTHER inversion 18451855
nsv819701 CNV insertion 19587683
nsv821609 CNV duplication 20802225
nsv8227 CNV gain+loss 18304495
nsv824360 CNV gain 20364138
nsv831174 CNV loss 17160897
nsv831175 CNV loss 17160897
nsv831176 CNV loss 17160897
nsv970955 CNV duplication 23825009
nsv970956 CNV duplication 23825009
nsv981601 CNV duplication 23825009

Additional Variant Information for CTAGE8 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CTAGE8

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CTAGE8 Gene

Disorders for CTAGE8 Gene

Additional Disease Information for CTAGE8

No disorders were found for CTAGE8 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTAGE8 Gene

Publications for CTAGE8 Gene

  1. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 3 4 58
  2. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  3. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R … Stanton LW (Nature biotechnology 2004) 3 58
  4. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 58
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3

Products for CTAGE8 Gene

Sources for CTAGE8 Gene

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