Aliases for CTAGE6 Gene

Aliases for CTAGE6 Gene

  • CTAGE Family Member 6 2 3 3 4 5
  • CTAGE Family, Member 6, Pseudogene 2 3
  • Protein CTAGE-6 3 4
  • CTAGE6P 3 4
  • Cutaneous T-Cell Lymphoma-Associated Antigen 6 3
  • Putative Protein CTAGE-6 3
  • CTAGE Family, Member 6 2

External Ids for CTAGE6 Gene

Previous HGNC Symbols for CTAGE6 Gene


Previous GeneCards Identifiers for CTAGE6 Gene

  • GC07M142844
  • GC07M142889
  • GC07M143083
  • GC07M143453
  • GC07M143455
  • GC07M143459
  • GC07M143461

Summaries for CTAGE6 Gene

GeneCards Summary for CTAGE6 Gene

CTAGE6 (CTAGE Family Member 6) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleotide binding. An important paralog of this gene is CTAGE15.

Additional gene information for CTAGE6 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CTAGE6 Gene

Genomics for CTAGE6 Gene

GeneHancer (GH) Regulatory Elements for CTAGE6 Gene

Promoters and enhancers for CTAGE6 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J143484 Enhancer 1.1 Ensembl ENCODE 7.4 +268.3 268349 11.2 CTCF JUND FOS ZNF10 REST AFF1 TRIM28 CUX1 EP300 CTBP1 OR2R1P TAS2R60 EPHA1-AS1 CTAGE6 EPHA1 ARHGEF35 ENSG00000253882 lnc-EPHA1-3
GH07J143498 Enhancer 0.8 Ensembl ENCODE 7.4 +258.8 258849 7.4 JUND REST NR2F2 FOS NRF1 CEBPG GATA2 CEBPB JUN GATA3 TAS2R41 FAM131B EPHA1-AS1 CTAGE6 TAS2R60 EPHA1 OR2A13P LOC105375547 piR-61945-474
GH07J143519 Enhancer 0.7 Ensembl ENCODE 4.8 +239.2 239249 4.6 ZIC2 REST ZFHX2 FEZF1 TAF1 GLIS1 SAP30 POLR2A SIN3A OR10AC1 TAS2R41 FAM131B TAS2R60 EPHA1 ARHGEF35 EPHA1-AS1 CTAGE6 EPHB6 OR2A7
GH07J143460 Enhancer 0.4 Ensembl 6.5 +295.3 295349 4 MITF CEBPB USF2 L3MBTL2 TAS2R60 EPHA1 CTAGE6 ENSG00000253882 AC073264 TAS2R41 EPHA1-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CTAGE6 on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CTAGE6

Top Transcription factor binding sites by QIAGEN in the CTAGE6 gene promoter:
  • c-Myb
  • Cart-1
  • Cdc5
  • CUTL1
  • Lhx3a
  • LHX3b
  • Msx-1
  • NCX
  • Pax-6
  • POU6F1 (c2)

Genomic Locations for CTAGE6 Gene

Genomic Locations for CTAGE6 Gene
2,662 bases
Minus strand
2,662 bases
Minus strand

Genomic View for CTAGE6 Gene

Genes around CTAGE6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CTAGE6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CTAGE6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CTAGE6 Gene

Proteins for CTAGE6 Gene

  • Protein details for CTAGE6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    cTAGE family member 6
    Protein Accession:
    Secondary Accessions:
    • A4FU29
    • Q3ZCM5

    Protein attributes for CTAGE6 Gene

    777 amino acids
    Molecular mass:
    87900 Da
    Quaternary structure:
    No Data Available
    • Sequence=BC043153; Type=Frameshift; Evidence={ECO:0000305};

neXtProt entry for CTAGE6 Gene

Post-translational modifications for CTAGE6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CTAGE6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CTAGE6 Gene

Domains & Families for CTAGE6 Gene

Gene Families for CTAGE6 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Protein Domains for CTAGE6 Gene


Suggested Antigen Peptide Sequences for CTAGE6 Gene

GenScript: Design optimal peptide antigens:
  • cTAGE family member 6 (CTGE6_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the cTAGE family.
  • Belongs to the cTAGE family.
genes like me logo Genes that share domains with CTAGE6: view

Function for CTAGE6 Gene

Phenotypes From GWAS Catalog for CTAGE6 Gene

genes like me logo Genes that share phenotypes with CTAGE6: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTAGE6

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CTAGE6 Gene

Localization for CTAGE6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CTAGE6 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CTAGE6 gene
Compartment Confidence
endoplasmic reticulum 3

Gene Ontology (GO) - Cellular Components for CTAGE6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
GO:0005789 endoplasmic reticulum membrane IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
GO:0070971 endoplasmic reticulum exit site IBA 21873635
genes like me logo Genes that share ontologies with CTAGE6: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CTAGE6 Gene

Pathways & Interactions for CTAGE6 Gene

PathCards logo

SuperPathways for CTAGE6 Gene

No Data Available

Interacting Proteins for CTAGE6 Gene

STRING Interaction Network Preview (showing top 2 STRING interactants - click image to see details)
STRING Interaction Network
Selected Interacting proteins: ENSP00000474388 Q86UF2-CTGE6_HUMAN for CTAGE6 Gene via STRING IID


Gene Ontology (GO) - Biological Process for CTAGE6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006888 ER to Golgi vesicle-mediated transport IBA 21873635
GO:0008150 biological_process ND --
GO:0009306 protein secretion IBA 21873635
GO:0035459 cargo loading into vesicle IBA 21873635
genes like me logo Genes that share ontologies with CTAGE6: view

No data available for Pathways by source and SIGNOR curated interactions for CTAGE6 Gene

Drugs & Compounds for CTAGE6 Gene

No Compound Related Data Available

Transcripts for CTAGE6 Gene

mRNA/cDNA for CTAGE6 Gene

4 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CTAGE6

Alternative Splicing Database (ASD) splice patterns (SP) for CTAGE6 Gene

No ASD Table

Relevant External Links for CTAGE6 Gene

GeneLoc Exon Structure for

Expression for CTAGE6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CTAGE6 Gene

mRNA differential expression in normal tissues according to GTEx for CTAGE6 Gene

This gene is overexpressed in Testis (x39.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CTAGE6 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CTAGE6

SOURCE GeneReport for Unigene cluster for CTAGE6 Gene:

genes like me logo Genes that share expression patterns with CTAGE6: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CTAGE6 Gene

Orthologs for CTAGE6 Gene

This gene was present in the common ancestor of animals.

Orthologs for CTAGE6 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC470576 30
  • 94.36 (n)
(Bos Taurus)
Mammalia -- 31
  • 71 (a)
(Mus musculus)
Mammalia Ctage5 31
  • 65 (a)
(Canis familiaris)
Mammalia -- 31
  • 44 (a)
(Monodelphis domestica)
Mammalia -- 31
  • 34 (a)
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 33 (a)
(Gallus gallus)
Aves -- 31
  • 30 (a)
(Anolis carolinensis)
Reptilia -- 31
  • 31 (a)
(Danio rerio)
Actinopterygii ctage5 31
  • 35 (a)
fruit fly
(Drosophila melanogaster)
Insecta Tango1 31
  • 9 (a)
Species where no ortholog for CTAGE6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CTAGE6 Gene

Gene Tree for CTAGE6 (if available)
Gene Tree for CTAGE6 (if available)

Paralogs for CTAGE6 Gene

Paralogs for CTAGE6 Gene

(7) SIMAP similar genes for CTAGE6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CTAGE6: view

Variants for CTAGE6 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CTAGE6 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs77246673 Benign: not specified 143,756,568(-) T/G MISSENSE_VARIANT

Additional dbSNP identifiers (rs#s) for CTAGE6 Gene

Structural Variations from Database of Genomic Variants (DGV) for CTAGE6 Gene

Variant ID Type Subtype PubMed ID
dgv12n29 CNV gain+loss 16826518
dgv250n111 CNV duplication 26073780
dgv251n111 CNV duplication 26073780
dgv6700n100 CNV gain 25217958
dgv6701n100 CNV gain 25217958
dgv6702n100 CNV gain 25217958
dgv6706n100 CNV loss 25217958
dgv6707n100 CNV loss 25217958
dgv6708n100 CNV loss 25217958
dgv6709n100 CNV loss 25217958
dgv6710n100 CNV loss 25217958
dgv6711n100 CNV gain 25217958
dgv6712n100 CNV loss 25217958
dgv6713n100 CNV gain 25217958
dgv6714n100 CNV gain+loss 25217958
dgv6715n100 CNV gain+loss 25217958
dgv6716n100 CNV gain 25217958
dgv6717n100 CNV gain+loss 25217958
dgv6718n100 CNV gain 25217958
esv2422489 CNV duplication 17116639
esv2759570 CNV gain+loss 17122850
esv2761113 CNV gain+loss 21179565
esv2761375 CNV gain 21179565
esv29816 CNV gain+loss 19812545
esv3364531 CNV duplication 20981092
esv3425779 CNV duplication 20981092
esv3584556 CNV gain 24956385
esv3891220 CNV loss 25118596
esv3891222 CNV gain+loss 25118596
nsv1015899 CNV loss 25217958
nsv1016831 CNV gain 25217958
nsv1017213 CNV gain+loss 25217958
nsv1017272 CNV gain 25217958
nsv1022655 CNV gain 25217958
nsv1024360 CNV gain+loss 25217958
nsv1029557 CNV gain+loss 25217958
nsv1033465 CNV gain 25217958
nsv1034865 CNV gain 25217958
nsv1140255 OTHER inversion 24896259
nsv1149977 CNV duplication 26484159
nsv1161631 CNV duplication 26073780
nsv1161646 CNV duplication 26073780
nsv16 OTHER inversion 15895083
nsv17 OTHER inversion 15895083
nsv428188 CNV gain+loss 18775914
nsv442210 CNV gain 18776908
nsv469570 CNV gain+loss 16826518
nsv471645 CNV gain+loss 15918152
nsv514455 CNV gain+loss 21397061
nsv522225 CNV gain 19592680
nsv608682 CNV gain 21841781
nsv608684 CNV loss 21841781
nsv608686 CNV loss 21841781
nsv608687 CNV gain 21841781
nsv7408 OTHER inversion 18451855
nsv8227 CNV gain+loss 18304495
nsv970953 CNV duplication 23825009

Variation tolerance for CTAGE6 Gene

Gene Damage Index Score: 2.44; 43.04% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CTAGE6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CTAGE6 Gene

Disorders for CTAGE6 Gene

Additional Disease Information for CTAGE6

No disorders were found for CTAGE6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CTAGE6 Gene

Publications for CTAGE6 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 54
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 54
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 54
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 54

Products for CTAGE6 Gene

Sources for CTAGE6 Gene