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Aliases for CT62 Gene

Aliases for CT62 Gene

  • Cancer/Testis Antigen 62 2 3 5

External Ids for CT62 Gene

Previous GeneCards Identifiers for CT62 Gene

  • GC15M069190
  • GC15M071402
  • GC15M048238

Summaries for CT62 Gene

GeneCards Summary for CT62 Gene

CT62 (Cancer/Testis Antigen 62) is a Protein Coding gene.

Additional gene information for CT62 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CT62 Gene

Genomics for CT62 Gene

GeneHancer (GH) Regulatory Elements for CT62 Gene

Promoters and enhancers for CT62 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15I071110 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 550.8 +1.3 1344 7.2 ARNT SIN3A FEZF1 ZNF2 ZBTB7B ZNF213 ZNF143 KLF13 DEK SP3 CT62 THSD4 RPL17P39
GH15I071261 Enhancer 0.3 FANTOM5 60.9 -145.7 -145669 0.1 LOC105370884 CT62 PIR59724 THSD4
GH15I071078 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 11.4 +35.4 35370 3.5 PKNOX1 SIN3A FEZF1 BMI1 BATF ZBTB7B ZNF335 SCRT2 FOS EGR2 CT62 THSD4 LOC105370886 RPL5P3
GH15I071135 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 11.6 -21.3 -21253 2.2 CTCF JUN ZIC2 ZFHX2 POLR2A PRDM10 ZNF600 FOS FOSL2 HLF MYO9A CT62 RPL17P39 GC15P071151 THSD4
GH15I071082 Enhancer 1.1 ENCODE dbSUPER 11.5 +32.2 32198 2.1 ZNF493 ZFP64 ZNF121 ZNF213 KLF7 ZNF548 ZNF202 SP3 JUNB REST RPL17P39 LRRC49 THAP10 CT62 LARP6 ENSG00000259744 TLE3 LOC105370886 RPL5P3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CT62 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CT62 Gene

Genomic Locations for CT62 Gene
chr15:71,110,244-71,115,500
(GRCh38/hg38)
Size:
5,257 bases
Orientation:
Minus strand
chr15:71,402,583-71,407,839
(GRCh37/hg19)

Genomic View for CT62 Gene

Genes around CT62 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CT62 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CT62 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CT62 Gene

Proteins for CT62 Gene

  • Protein details for CT62 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C5K7-CT62_HUMAN
    Recommended name:
    Cancer/testis antigen 62
    Protein Accession:
    P0C5K7

    Protein attributes for CT62 Gene

    Size:
    136 amino acids
    Molecular mass:
    15412 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CT62 Gene

Post-translational modifications for CT62 Gene

No Post-translational modifications

Other Protein References for CT62 Gene

No data available for DME Specific Peptides for CT62 Gene

Domains & Families for CT62 Gene

Gene Families for CT62 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CT62 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for CT62 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CT62: view

No data available for UniProtKB/Swiss-Prot for CT62 Gene

Function for CT62 Gene

Phenotypes From GWAS Catalog for CT62 Gene

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CT62 Gene

Localization for CT62 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CT62 gene
Compartment Confidence
extracellular 2
nucleus 2
cytosol 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CT62 Gene

Pathways & Interactions for CT62 Gene

No Data Available

Interacting Proteins for CT62 Gene

Gene Ontology (GO) - Biological Process for CT62 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CT62 Gene

Drugs & Compounds for CT62 Gene

No Compound Related Data Available

Transcripts for CT62 Gene

mRNA/cDNA for CT62 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CT62 Gene

Cancer/testis antigen 62:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CT62 Gene

No ASD Table

Relevant External Links for CT62 Gene

GeneLoc Exon Structure for
CT62
ECgene alternative splicing isoforms for
CT62

Expression for CT62 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CT62 Gene

mRNA differential expression in normal tissues according to GTEx for CT62 Gene

This gene is overexpressed in Testis (x44.2).

NURSA nuclear receptor signaling pathways regulating expression of CT62 Gene:

CT62

SOURCE GeneReport for Unigene cluster for CT62 Gene:

Hs.646533

mRNA Expression by UniProt/SwissProt for CT62 Gene:

P0C5K7-CT62_HUMAN
Tissue specificity: Testis specific. Expressed in cancer cell lines.
genes like me logo Genes that share expression patterns with CT62: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CT62 Gene

Orthologs for CT62 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CT62 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CT62 33 34
  • 99.02 (n)
Species where no ortholog for CT62 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CT62 Gene

ENSEMBL:
Gene Tree for CT62 (if available)
TreeFam:
Gene Tree for CT62 (if available)

Paralogs for CT62 Gene

No data available for Paralogs for CT62 Gene

Variants for CT62 Gene

Sequence variations from dbSNP and Humsavar for CT62 Gene

SNP ID Clin Chr 15 pos Variation AA Info Type
rs1000897209 -- 71,112,602(-) G/A intron_variant
rs1001535440 -- 71,114,818(-) C/T intron_variant
rs1002923384 -- 71,110,156(-) G/A downstream_transcript_variant
rs1003104479 -- 71,115,658(-) G/A upstream_transcript_variant
rs1003234091 -- 71,117,147(-) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CT62 Gene

Variant ID Type Subtype PubMed ID
nsv569817 CNV gain 21841781
nsv1046192 CNV gain 25217958
nsv1043423 CNV loss 25217958
esv3569664 CNV gain 25503493

Variation tolerance for CT62 Gene

Residual Variation Intolerance Score: 64.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.19; 4.20% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CT62 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CT62

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CT62 Gene

Disorders for CT62 Gene

Additional Disease Information for CT62

No disorders were found for CT62 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CT62 Gene

Publications for CT62 Gene

  1. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. (PMID: 15905330) Chen YT … Simpson AJ (Proceedings of the National Academy of Sciences of the United States of America 2005) 2 3 4 58
  2. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PMID: 23400010) Del-Aguila JL … Boerwinkle E (The pharmacogenomics journal 2014) 3 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CT62 Gene

Sources for CT62 Gene

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