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Aliases for CT55 Gene

Aliases for CT55 Gene

  • Cancer/Testis Antigen 55 2 3 3 5
  • Tumor Antigen BJ-HCC-20 3 4
  • CXorf48 3 4
  • Chromosome X Open Reading Frame 48 2
  • BRCA2-Interacting Protein 3
  • BJHCC20A 3

External Ids for CT55 Gene

Previous HGNC Symbols for CT55 Gene

  • CXorf48

Previous GeneCards Identifiers for CT55 Gene

  • GC0XM134291

Summaries for CT55 Gene

GeneCards Summary for CT55 Gene

CT55 (Cancer/Testis Antigen 55) is a Protein Coding gene.

Additional gene information for CT55 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CT55 Gene

Genomics for CT55 Gene

GeneHancer (GH) Regulatory Elements for CT55 Gene

Promoters and enhancers for CT55 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ135171 Promoter 1 EPDnew 650.7 +0.4 409 0.1 CTCF HDAC1 MEIS2 ATF1 NFRKB E4F1 POLR2B MTA3 DIDO1 POLR2A CT55 LOC100419791
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CT55 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CT55 Gene

Genomic Locations for CT55 Gene
chrX:135,156,536-135,171,827
(GRCh38/hg38)
Size:
15,292 bases
Orientation:
Minus strand
chrX:134,290,461-134,305,751
(GRCh37/hg19)
Size:
15,291 bases
Orientation:
Minus strand

Genomic View for CT55 Gene

Genes around CT55 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CT55 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CT55 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CT55 Gene

Proteins for CT55 Gene

  • Protein details for CT55 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WUE5-CT55_HUMAN
    Recommended name:
    Cancer/testis antigen 55
    Protein Accession:
    Q8WUE5
    Secondary Accessions:
    • Q9NWY8

    Protein attributes for CT55 Gene

    Size:
    264 amino acids
    Molecular mass:
    29052 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CT55 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CT55 Gene

Post-translational modifications for CT55 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CT55 Gene

No data available for DME Specific Peptides for CT55 Gene

Domains & Families for CT55 Gene

Gene Families for CT55 Gene

Human Protein Atlas (HPA):
  • Predicted secreted proteins

Protein Domains for CT55 Gene

Suggested Antigen Peptide Sequences for CT55 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CT55: view

No data available for UniProtKB/Swiss-Prot for CT55 Gene

Function for CT55 Gene

Gene Ontology (GO) - Molecular Function for CT55 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with CT55: view
genes like me logo Genes that share phenotypes with CT55: view

Animal Model Products

miRNA for CT55 Gene

miRTarBase miRNAs that target CT55

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CT55 Gene

Localization for CT55 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CT55 gene
Compartment Confidence
mitochondrion 2
cytosol 2
extracellular 1
peroxisome 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CT55 Gene

Pathways & Interactions for CT55 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CT55 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CT55 Gene

Drugs & Compounds for CT55 Gene

No Compound Related Data Available

Transcripts for CT55 Gene

mRNA/cDNA for CT55 Gene

(3) REFSEQ mRNAs :
(20) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CT55 Gene

No ASD Table

Relevant External Links for CT55 Gene

GeneLoc Exon Structure for
CT55
ECgene alternative splicing isoforms for
CT55

Expression for CT55 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CT55 Gene

mRNA differential expression in normal tissues according to GTEx for CT55 Gene

This gene is overexpressed in Testis (x21.4).

Protein differential expression in normal tissues from HIPED for CT55 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CT55 Gene



Protein tissue co-expression partners for CT55 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of CT55 Gene:

CT55
genes like me logo Genes that share expression patterns with CT55: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CT55 Gene

Orthologs for CT55 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CT55 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CT55 34
  • 98 (a)
OneToOne
LOC465871 33
  • 94.4 (n)
cow
(Bos Taurus)
Mammalia CT55 34 33
  • 71.67 (n)
OneToOne
dog
(Canis familiaris)
Mammalia LOC492152 33
  • 69.86 (n)
mouse
(Mus musculus)
Mammalia Gm14597 34
  • 30 (a)
OneToOne
Species where no ortholog for CT55 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CT55 Gene

ENSEMBL:
Gene Tree for CT55 (if available)
TreeFam:
Gene Tree for CT55 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CT55: view image

Paralogs for CT55 Gene

(1) SIMAP similar genes for CT55 Gene using alignment to 1 proteins:

  • CT55_HUMAN

Pseudogenes.org Pseudogenes for CT55 Gene

genes like me logo Genes that share paralogs with CT55: view

No data available for Paralogs for CT55 Gene

Variants for CT55 Gene

Sequence variations from dbSNP and Humsavar for CT55 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs111378411 -- 135,158,618(-) T/G intron_variant
rs111527783 -- 135,159,600(-) T/C intron_variant
rs111593484 -- 135,164,100(-) G/A intron_variant
rs111629738 -- 135,158,131(-) T/G intron_variant
rs112085692 -- 135,169,968(-) T/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CT55 Gene

Variant ID Type Subtype PubMed ID
dgv2433e212 CNV gain 25503493
esv2758894 CNV gain 17122850
esv3577267 CNV gain 25503493
nsv469825 CNV loss 16826518
nsv7458 OTHER inversion 18451855

Variation tolerance for CT55 Gene

Residual Variation Intolerance Score: 68% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.09; 1.95% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CT55 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CT55

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CT55 Gene

Disorders for CT55 Gene

Additional Disease Information for CT55

No disorders were found for CT55 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CT55 Gene

Publications for CT55 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  5. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58

Products for CT55 Gene

Sources for CT55 Gene

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