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CSN3 (Casein Kappa) is a Protein Coding gene. Diseases associated with CSN3 include Milk Allergy and Cow Milk Allergy.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH04J070238 | Promoter | 0.3 | EPDnew | 600.7 | 0.0 | -7 | 0.1 | CSN3 piR-34009-017 FDCSP | ||
GH04J070242 | Promoter | 0.3 | EPDnew | 600.7 | +4.2 | 4208 | 0.1 | CSN3 HSALNG0035023 CABS1 | ||
GH04J070295 | Enhancer | 0.5 | dbSUPER | 0.2 | +59.8 | 59788 | 5.7 | ZNF316 MAFF MAFK MAFG EMSY | piR-38352-416 piR-55361-423 CABS1 CSN3 | |
GH04J070313 | Enhancer | 0.3 | Ensembl | 0.2 | +75.3 | 75331 | 0.2 | EZH2 | SMR3A OPRPN piR-55361-423 CABS1 piR-38352-416 CSN3 | |
GH04J070334 | Promoter | 0.3 | EPDnew | 0.2 | +96.6 | 96592 | 0.1 | CABS1 piR-55361-423 CSN3 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0005515 | protein binding | IPI | 25416956 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS | -- |
GO:0005615 | extracellular space | IBA,IDA | 7979373 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007595 | lactation | IBA,IDA | 7979373 |
GO:0050821 | protein stabilization | IBA,IDA | 7979373 |
GO:0055085 | transmembrane transport | TAS | -- |
Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
---|---|---|---|---|---|---|
fostamatinib | Approved, Investigational | Pharma | Target, inhibitor | Kinase Inhibitors | 0 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
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This gene was present in the common ancestor of mammals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CSN3 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CSN3 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CSN3 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Csn3 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Csn3 30 17 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 04 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1048152 | - | p.Arg110Leu | |||
rs17850702 | - | p.Tyr75Cys | |||
rs3775739 | - | p.Ala145Thr |
Disorder | Aliases | PubMed IDs |
---|---|---|
milk allergy |
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cow milk allergy |
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food allergy |
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mastitis |
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epilepsy, juvenile absence 1 |
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