Aliases for CSF3 Gene
External Ids for CSF3 Gene
Previous HGNC Symbols for CSF3 Gene
Previous GeneCards Identifiers for CSF3 Gene
This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2020]
GeneCards Summary for CSF3 Gene
CSF3 (Colony Stimulating Factor 3) is a Protein Coding gene. Diseases associated with CSF3 include Neutropenia and Mucositis. Among its related pathways are PEDF Induced Signaling and Cytokine production by Th17 cells in CF (Mouse model). Gene Ontology (GO) annotations related to this gene include enzyme binding and growth factor activity.
UniProtKB/Swiss-Prot Summary for CSF3 Gene
Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.