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Aliases for CSAG3 Gene

Aliases for CSAG3 Gene

  • CSAG Family Member 3 2 3 5
  • Taxol-Resistant-Associated Gene 3 Protein 3 4
  • Cancer/Testis Antigen 24.2 3 4
  • CSAG Family, Member 3A 2 3
  • CT24.2 3 4
  • CSAG3A 3 4
  • Chondrosarcoma-Associated Gene 2/3 Protein 3
  • Taxol Resistance Associated Gene 3 3
  • CSAG Family, Member 3 2
  • CSAG2 CSAG3 4
  • TRAG-3 4
  • TRAG3 4

External Ids for CSAG3 Gene

Previous HGNC Symbols for CSAG3 Gene

  • CSAG3A

Previous GeneCards Identifiers for CSAG3 Gene

  • GC0XM151630
  • GC0XM151876
  • GC0XP140729

Summaries for CSAG3 Gene

GeneCards Summary for CSAG3 Gene

CSAG3 (CSAG Family Member 3) is a Protein Coding gene. Diseases associated with CSAG3 include Chondrosarcoma. An important paralog of this gene is CSAG2.

UniProtKB/Swiss-Prot for CSAG3 Gene

  • Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.

Additional gene information for CSAG3 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CSAG3 Gene

Genomics for CSAG3 Gene

GeneHancer (GH) Regulatory Elements for CSAG3 Gene

Promoters and enhancers for CSAG3 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI152753 Promoter 0.5 EPDnew 550.8 -0.1 -61 0.1 MAGEA2 CSAG3 ENSG00000231447 GC0XM152591
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CSAG3 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the CSAG3 gene promoter:

Genomic Locations for CSAG3 Gene

Genomic Locations for CSAG3 Gene
6,302 bases
Plus strand

Genomic View for CSAG3 Gene

Genes around CSAG3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CSAG3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CSAG3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CSAG3 Gene

Proteins for CSAG3 Gene

  • Protein details for CSAG3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Chondrosarcoma-associated gene 2/3 protein
    Protein Accession:
    Secondary Accessions:
    • O75605
    • Q0VDC3
    • Q96IU8

    Protein attributes for CSAG3 Gene

    127 amino acids
    Molecular mass:
    14430 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CSAG3 Gene


neXtProt entry for CSAG3 Gene

Post-translational modifications for CSAG3 Gene

No Post-translational modifications

Other Protein References for CSAG3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CSAG3 Gene

Domains & Families for CSAG3 Gene

Gene Families for CSAG3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CSAG3 Gene


Suggested Antigen Peptide Sequences for CSAG3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CSAG3: view

No data available for UniProtKB/Swiss-Prot for CSAG3 Gene

Function for CSAG3 Gene

Molecular function for CSAG3 Gene

UniProtKB/Swiss-Prot Function:
Drug-resistance related protein, its expression is associated with the chemotherapy resistant and neoplastic phenotype. May also be linked to the malignant phenotype.

Phenotypes for CSAG3 Gene

GenomeRNAi human phenotypes for CSAG3:
genes like me logo Genes that share phenotypes with CSAG3: view

Animal Model Products

Inhibitory RNA Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CSAG3 Gene

Localization for CSAG3 Gene

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for CSAG3 Gene

Pathways & Interactions for CSAG3 Gene

SuperPathways for CSAG3 Gene

No Data Available

Interacting Proteins for CSAG3 Gene

Gene Ontology (GO) - Biological Process for CSAG3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042493 response to drug TAS 10095106
genes like me logo Genes that share ontologies with CSAG3: view

No data available for Pathways by source and SIGNOR curated interactions for CSAG3 Gene

Drugs & Compounds for CSAG3 Gene

No Compound Related Data Available

Transcripts for CSAG3 Gene

mRNA/cDNA for CSAG3 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for CSAG3 Gene

No ASD Table

Relevant External Links for CSAG3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CSAG3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CSAG3 Gene

NURSA nuclear receptor signaling pathways regulating expression of CSAG3 Gene:


mRNA Expression by UniProt/SwissProt for CSAG3 Gene:

Tissue specificity: Weakly expressed in kidney. Expressed in various tumor cell lines including carcinomas, myeloid and lymphoid malignancies, melanomas and prostate cancer. Overexpressed in taxol-resistant breast cancer line MDA 435TR and the doxorubicin-resistant multiple myelanoma lines RPMI-8226/Dox40 and RPMI-8226/MDR10V.
genes like me logo Genes that share expression patterns with CSAG3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CSAG3 Gene

Orthologs for CSAG3 Gene

Evolution for CSAG3 Gene

Gene Tree for CSAG3 (if available)
Gene Tree for CSAG3 (if available)

No data available for Orthologs for CSAG3 Gene

Paralogs for CSAG3 Gene

Paralogs for CSAG3 Gene

(1) SIMAP similar genes for CSAG3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CSAG3: view

Variants for CSAG3 Gene

Sequence variations from dbSNP and Humsavar for CSAG3 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs184236067 -- 152,753,670(+) C/G upstream_transcript_variant
rs1894361 -- 152,752,537(+) C/A/T upstream_transcript_variant
rs200100719 -- 152,759,368(+) ATA/A 5_prime_UTR_variant, intron_variant
rs201532657 -- 152,754,691(+) ATTCA/ATTCATTCA genic_upstream_transcript_variant, intron_variant
rs3020650 -- 152,753,514(+) G/A upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for CSAG3 Gene

Variant ID Type Subtype PubMed ID
esv2758901 CNV gain 17122850

Additional Variant Information for CSAG3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for CSAG3 Gene

Disorders for CSAG3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CSAG3 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • chondrosarcoma of bone
- elite association - COSMIC cancer census association via MalaCards
Search CSAG3 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CSAG3

genes like me logo Genes that share disorders with CSAG3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CSAG3 Gene

Publications for CSAG3 Gene

  1. TRAG-3, a novel gene, isolated from a taxol-resistant ovarian carcinoma cell line. (PMID: 10095106) Duan Z … Seiden MV (Gene 1999) 3 4 58
  2. Human tumor antigen-specific helper and regulatory T cells share common epitope specificity but exhibit distinct T cell repertoire. (PMID: 20483736) Fourcade J … Zarour HM (Journal of immunology (Baltimore, Md. : 1950) 2010) 3 58
  3. Coordinated expression of clustered cancer/testis genes encoded in a large inverted repeat DNA structure. (PMID: 18395366) Bredenbeck A … Losch FO (Gene 2008) 3 58
  4. Taxol-resistance-associated gene-3 (TRAG-3/CSAG2) expression is predictive for clinical outcome in ovarian carcinoma patients. (PMID: 17216190) Materna V … Lage H (Virchows Archiv : an international journal of pathology 2007) 3 58
  5. Expression of the TRAG-3 gene in human esophageal cancer: the frequent synchronous expression of MAGE-3 gene. (PMID: 16685391) Ohta M … Mori M (Oncology reports 2006) 3 58

Products for CSAG3 Gene

Sources for CSAG3 Gene

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