Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quin... See more...

Aliases for CRYZ Gene

Aliases for CRYZ Gene

  • Crystallin Zeta 2 3 5
  • NADPH:Quinone Reductase 2 3 4
  • Quinone Oxidoreductase 2 3 4
  • Crystallin, Zeta (Quinone Reductase) 2 3
  • EC 1.6.5.5 4 51
  • Epididymis Secretory Sperm Binding Protein 3
  • Zeta-Crystallin 4
  • CRYZ 5

External Ids for CRYZ Gene

Previous GeneCards Identifiers for CRYZ Gene

  • GC01M075290
  • GC01M074149
  • GC01M074533
  • GC01M074541
  • GC01M074883
  • GC01M074943
  • GC01M075171
  • GC01M073305

Summaries for CRYZ Gene

Entrez Gene Summary for CRYZ Gene

  • Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq, Sep 2008]

GeneCards Summary for CRYZ Gene

CRYZ (Crystallin Zeta) is a Protein Coding gene. Diseases associated with CRYZ include Septic Myocarditis. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and mRNA 3'-UTR binding. An important paralog of this gene is VAT1.

UniProtKB/Swiss-Prot Summary for CRYZ Gene

  • Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.

Gene Wiki entry for CRYZ Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CRYZ Gene

Genomics for CRYZ Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CRYZ Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J074729 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 327.2 +0.9 884 5.4 TBP MXD4 CEBPA SIX5 NR2C1 MNT IKZF1 SMAD5 ETS1 MBD2 CRYZ TYW3 RF00017-248 ERICH3
GH01J075136 Promoter/Enhancer 1.4 Ensembl ENCODE CraniofacialAtlas 5.7 -405.6 -405592 9.6 SIN3A ZNF189 CBX2 ZFP36 EGR1 ZNF384 ZFX ZNF561 TRIM28 L3MBTL2 SLC44A5 CRYZ ENSG00000272864 ENSG00000224127 LHX8 HSALNG0004518
GH01J075073 Enhancer 1 FANTOM5 Ensembl ENCODE 4 -343.6 -343593 6.8 ELF1 CEBPB EP300 CTBP1 ZBTB40 SPI1 SMARCE1 RCOR1 SP1 GATA2 TYW3 CRYZ HSALNG0004515 piR-33432-018 LHX8
GH01J075083 Enhancer 0.7 Ensembl ENCODE 4.2 -350.1 -350136 2.7 CEBPB MAFF EP300 ZNF316 MAFK JUND POU5F1 NANOG MSH4 CRYZ HSALNG0004515 piR-33432-018 LHX8
GH01J074780 Enhancer 0.3 Ensembl 0.3 -47.4 -47393 0.8 MAFK HSALNG0004506 HSALNG0004505 CRYZ LHX8
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CRYZ on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CRYZ

Top Transcription factor binding sites by QIAGEN in the CRYZ gene promoter:
  • COUP
  • COUP-TF
  • COUP-TF1
  • HNF-4alpha1
  • HNF-4alpha2
  • Meis-1
  • Meis-1a
  • Meis-1b
  • Pax-4a
  • SRY

Genomic Locations for CRYZ Gene

Latest Assembly
chr1:74,705,470-74,733,408
(GRCh38/hg38)
Size:
27,939 bases
Orientation:
Minus strand

Previous Assembly
chr1:75,171,170-75,198,734
(GRCh37/hg19 by Entrez Gene)
Size:
27,565 bases
Orientation:
Minus strand

chr1:75,171,170-75,199,092
(GRCh37/hg19 by Ensembl)
Size:
27,923 bases
Orientation:
Minus strand

Genomic View for CRYZ Gene

Genes around CRYZ on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CRYZ Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CRYZ Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CRYZ Gene

Proteins for CRYZ Gene

  • Protein details for CRYZ Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08257-QOR_HUMAN
    Recommended name:
    Quinone oxidoreductase
    Protein Accession:
    Q08257
    Secondary Accessions:
    • A6NN60
    • D3DQ76
    • Q53FT0
    • Q59EU7
    • Q5HYE7
    • Q6NSK9

    Protein attributes for CRYZ Gene

    Size:
    329 amino acids
    Molecular mass:
    35207 Da
    Quaternary structure:
    • Homotetramer.

    Three dimensional structures from OCA and Proteopedia for CRYZ Gene

    Alternative splice isoforms for CRYZ Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CRYZ Gene

Selected DME Specific Peptides for CRYZ Gene

Q08257:
  • VLQNGAHEVFNH
  • SSTKEEFQQ
  • EINPRDTM
  • AGESVLVHGASGGVGLA

Post-translational modifications for CRYZ Gene

  • Ubiquitination at Lys23
  • Modification sites at PhosphoSitePlus

Domains & Families for CRYZ Gene

Gene Families for CRYZ Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for CRYZ Gene

InterPro:
Blocks:
  • Quinone oxidoreductase/zeta-crystallin
  • Alcohol dehydrogenase GroES-like
ProtoNet:

Suggested Antigen Peptide Sequences for CRYZ Gene

GenScript: Design optimal peptide antigens:
  • Zeta-crystallin (QOR_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q08257

UniProtKB/Swiss-Prot:

QOR_HUMAN :
  • Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
Family:
  • Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
genes like me logo Genes that share domains with CRYZ: view

Function for CRYZ Gene

Molecular function for CRYZ Gene

UniProtKB/Swiss-Prot Function:
Does not have alcohol dehydrogenase activity. Binds NADP and acts through a one-electron transfer process. Orthoquinones, such as 1,2-naphthoquinone or 9,10-phenanthrenequinone, are the best substrates (in vitro). May act in the detoxification of xenobiotics. Interacts with (AU)-rich elements (ARE) in the 3'-UTR of target mRNA species. Enhances the stability of mRNA coding for BCL2. NADPH binding interferes with mRNA binding.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=2 a quinone + H(+) + NADPH = 2 a 1,4-benzosemiquinone + NADP(+); Xref=Rhea:RHEA:14269, ChEBI:CHEBI:15378, ChEBI:CHEBI:57783, ChEBI:CHEBI:58349, ChEBI:CHEBI:132124, ChEBI:CHEBI:134225; EC=1.6.5.5; Evidence={ECO:0000269|PubMed:17497241};.
GENATLAS Biochemistry:
crystallin,zeta polypeptide (quinone reductase)

Enzyme Numbers (IUBMB) for CRYZ Gene

Phenotypes From GWAS Catalog for CRYZ Gene

Gene Ontology (GO) - Molecular Function for CRYZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IEA --
GO:0003730 mRNA 3'-UTR binding IDA 17497241
GO:0003960 NADPH:quinone reductase activity IBA,IDA 17497241
GO:0008270 zinc ion binding IEA --
GO:0016491 oxidoreductase activity IEA --
genes like me logo Genes that share ontologies with CRYZ: view
genes like me logo Genes that share phenotypes with CRYZ: view

Animal Models for research

  • Taconic Biosciences Mouse Models for CRYZ

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CRYZ

Clone products for research

  • Addgene plasmids for CRYZ

No data available for Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CRYZ Gene

Localization for CRYZ Gene

Subcellular locations from UniProtKB/Swiss-Prot for CRYZ Gene

Cytoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CRYZ gene
Compartment Confidence
cytosol 5
extracellular 4
nucleus 3
plasma membrane 2
cytoskeleton 2
mitochondrion 2
peroxisome 2
endoplasmic reticulum 2
golgi apparatus 2
endosome 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CRYZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IBA,IDA 17497241
GO:0070062 extracellular exosome HDA 19056867
genes like me logo Genes that share ontologies with CRYZ: view

Pathways & Interactions for CRYZ Gene

PathCards logo

SuperPathways for CRYZ Gene

No Data Available

Gene Ontology (GO) - Biological Process for CRYZ Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007601 visual perception TAS 7835889
GO:0042178 xenobiotic catabolic process IDA 17497241
GO:0051289 protein homotetramerization IPI 17497241
GO:0055114 oxidation-reduction process IEA --
genes like me logo Genes that share ontologies with CRYZ: view

No data available for Pathways by source and SIGNOR curated interactions for CRYZ Gene

Drugs & Compounds for CRYZ Gene

(6) Drugs for CRYZ Gene - From: DrugBank and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Dicumarol Approved Pharma Target, inhibitor 0
cannabidiol Approved, Investigational Pharma Enzyme 0
NADP Experimental Pharma Target 0
Medical Cannabis Experimental, Investigational Pharma Target, inhibitor 0
NADPH Experimental Pharma 0

(1) Additional Compounds for CRYZ Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Quinone
  • 1,4-Benzochinon
  • 2,5-Cyclohexadiene-1,4-dione
  • Benzo-1,4-quinone
  • Benzoquinone
  • p-Benzoquinone
106-51-4
genes like me logo Genes that share compounds with CRYZ: view

Transcripts for CRYZ Gene

mRNA/cDNA for CRYZ Gene

4 REFSEQ mRNAs :
14 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CRYZ

Clone products for research

  • Addgene plasmids for CRYZ

Alternative Splicing Database (ASD) splice patterns (SP) for CRYZ Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12a · 12b · 12c · 12d
SP1: - - - - - -
SP2: - - -
SP3: - - - - - - -
SP4: - - - -
SP5: - - - - - - - - -
SP6: - - - - - - -
SP7: - - - -
SP8: - - -
SP9: - - -
SP10:
SP11: - - -
SP12: - - -
SP13:

Relevant External Links for CRYZ Gene

GeneLoc Exon Structure for
CRYZ

Expression for CRYZ Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CRYZ Gene

mRNA differential expression in normal tissues according to GTEx for CRYZ Gene

This gene is overexpressed in Liver (x5.9) and Kidney - Cortex (x4.2).

Protein differential expression in normal tissues from HIPED for CRYZ Gene

This gene is overexpressed in Liver, secretome (13.8) and Kidney (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CRYZ Gene



Protein tissue co-expression partners for CRYZ Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CRYZ

SOURCE GeneReport for Unigene cluster for CRYZ Gene:

Hs.83114

mRNA Expression by UniProt/SwissProt for CRYZ Gene:

Q08257-QOR_HUMAN
Tissue specificity: Only very low amounts in the lens.

Evidence on tissue expression from TISSUES for CRYZ Gene

  • Liver(4.8)
  • Nervous system(4.7)
  • Kidney(4.7)
  • Lung(4.5)
  • Heart(3.2)
  • Muscle(2.5)
  • Skin(2.4)
  • Intestine(2.3)
  • Blood(2.2)
  • Pancreas(2.2)
  • Stomach(2.2)
  • Adrenal gland(2.1)
  • Thyroid gland(2.1)
genes like me logo Genes that share expression patterns with CRYZ: view

Primer products for research

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for CRYZ Gene

Orthologs for CRYZ Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for CRYZ Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CRYZ 30 31
  • 98.38 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CRYZ 30 31
  • 88.35 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CRYZ 30 31
  • 86.32 (n)
OneToMany
-- 31
  • 77 (a)
OneToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 31
  • 83 (a)
OneToMany
-- 31
  • 81 (a)
OneToMany
Mouse
(Mus musculus)
Mammalia Cryz 30 17 31
  • 79.03 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Cryz 30
  • 78.12 (n)
Oppossum
(Monodelphis domestica)
Mammalia CRYZ 31
  • 63 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CRYZ 30 31
  • 67.89 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CRYZ 31
  • 66 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia cryz 30
  • 67.17 (n)
Str.8276 30
Zebrafish
(Danio rerio)
Actinopterygii cryz 30 31
  • 65.54 (n)
OneToOne
Dr.14514 30
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5597 30
Worm
(Caenorhabditis elegans)
Secernentea F39B2.3 30 31 32
  • 50.8 (n)
OneToOne
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ZTA1 31
  • 25 (a)
OneToMany
-- 33
-- 33
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.1760 31
  • 50 (a)
OneToOne
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.728 30
Species where no ortholog for CRYZ was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for CRYZ Gene

ENSEMBL:
Gene Tree for CRYZ (if available)
TreeFam:
Gene Tree for CRYZ (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CRYZ: view image

Paralogs for CRYZ Gene

(4) SIMAP similar genes for CRYZ Gene using alignment to 3 proteins:

  • QOR_HUMAN
  • A6NP24_HUMAN
  • C9JH92_HUMAN

Pseudogenes.org Pseudogenes for CRYZ Gene

genes like me logo Genes that share paralogs with CRYZ: view

Variants for CRYZ Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CRYZ Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
rs139734636 Likely Benign: not provided 74,719,373(-) C/T
NM_001889.4(CRYZ):c.265-1G>A
SPLICE_ACCEPTOR_VARIANT,INTRON
rs147597121 Benign: not provided 74,706,373(-) A/G
NM_001889.4(CRYZ):c.913T>C (p.Leu305=)
SYNONYMOUS
rs17095822 Benign: not provided. - 74,710,181(-) C/Tp.Glu183Lys
NM_001889.4(CRYZ):c.547G>A (p.Glu183Lys)
MISSENSE
rs6668086 Likely Benign: not provided 74,707,102(-) C/T
NM_001889.4(CRYZ):c.732+1G>A
SPLICE_DONOR_VARIANT,INTRON
rs11551729 - p.Pro66Ser

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CRYZ Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CRYZ Gene

Variant ID Type Subtype PubMed ID
esv21668 CNV gain 19812545
esv2662359 CNV deletion 23128226
esv2668367 CNV deletion 23128226
esv2762153 CNV gain 21179565
esv3564204 CNV deletion 23714750
esv3577964 CNV loss 25503493
esv3586466 CNV loss 21293372
esv3586467 CNV loss 21293372
nsv1002115 CNV gain 25217958
nsv1422 CNV insertion 18451855
nsv509346 CNV insertion 20534489
nsv546579 CNV loss 21841781
nsv830259 CNV gain 17160897

Variation tolerance for CRYZ Gene

Residual Variation Intolerance Score: 73.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 11.06; 92.16% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CRYZ Gene

Human Gene Mutation Database (HGMD)
CRYZ
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CRYZ

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CRYZ Gene

Disorders for CRYZ Gene

MalaCards: The human disease database

(1) MalaCards diseases for CRYZ Gene - From: COP

Disorder Aliases PubMed IDs
septic myocarditis
- elite association - COSMIC cancer census association via MalaCards
Search CRYZ in MalaCards View complete list of genes associated with diseases

Additional Disease Information for CRYZ

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with CRYZ: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CRYZ Gene

Publications for CRYZ Gene

  1. Organization of the human zeta-crystallin/quinone reductase gene (CRYZ). (PMID: 8088825) Gonzalez P … Zigler JS (Genomics 1994) 3 4 23
  2. zeta-Crystallin is a bcl-2 mRNA binding protein involved in bcl-2 overexpression in T-cell acute lymphocytic leukemia. (PMID: 20103721) Lapucci A … Capaccioli S (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010) 3 4
  3. Human and yeast zeta-crystallins bind AU-rich elements in RNA. (PMID: 17497241) Fernández MR … Parés X (Cellular and molecular life sciences : CMLS 2007) 3 4
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4

Products for CRYZ Gene

Sources for CRYZ Gene