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Aliases for CROCC2 Gene

Aliases for CROCC2 Gene

  • Ciliary Rootlet Coiled-Coil, Rootletin Family Member 2 2 3 5
  • Putative Ciliary Rootlet Coiled-Coil Protein-Like 3 Protein 3
  • Putative Ciliary Rootlet Coiled-Coil Protein 2 3
  • Rootletin-Like 3

External Ids for CROCC2 Gene

Summaries for CROCC2 Gene

GeneCards Summary for CROCC2 Gene

CROCC2 (Ciliary Rootlet Coiled-Coil, Rootletin Family Member 2) is a Protein Coding gene. An important paralog of this gene is CROCC.

Additional gene information for CROCC2 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CROCC2 Gene

Genomics for CROCC2 Gene

GeneHancer (GH) Regulatory Elements for CROCC2 Gene

Promoters and enhancers for CROCC2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J240912 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +9.3 9294 5.8 ARID4B KLF17 ZNF2 RAD21 ZNF614 GLIS2 ZNF143 FOS THAP11 ZNF654 C2orf54 AGXT ENSG00000223991 SNED1 GPC1 RNPEPL1 CROCC2 GC02M240925
GH02J240895 Enhancer 1.2 Ensembl ENCODE dbSUPER 0.4 -9.0 -8985 3.9 PKNOX1 ARID4B KLF17 KLF14 ZNF48 RAD21 RARA ZEB1 ZNF614 GLIS2 C2orf54 AGXT CROCC2
GH02J240920 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 0.4 +17.5 17458 6.6 HIC1 XRCC5 NFIC NFIB GLIS1 FOS ZBTB7A LOC200772 C2orf54 SNED1 GPC1 PASK CROCC2 GC02M240925
GH02J240959 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.2 +55.4 55367 5.2 FOXA2 ARNT MLX ARID4B FEZF1 DMAP1 ZNF48 YY1 ZNF207 RXRA ENSG00000223374 ENSG00000235861 OR5S1P LOC200772 C2orf54 MTERF4 SNED1 GC02M240925 CROCC2
GH02J240990 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.2 +85.6 85601 2.2 PKNOX1 FOXA2 SAP130 JUN MAX BMI1 YY1 FOSL1 SCRT2 FOSL2 SNED1 PPP1R7 ENSG00000223991 CROCC2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CROCC2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for CROCC2 Gene

Genomic Locations for CROCC2 Gene
86,982 bases
Plus strand
74,527 bases
Plus strand

Genomic View for CROCC2 Gene

Genes around CROCC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CROCC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CROCC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CROCC2 Gene

Proteins for CROCC2 Gene

  • Protein details for CROCC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative ciliary rootlet coiled-coil protein 2
    Protein Accession:

    Protein attributes for CROCC2 Gene

    1655 amino acids
    Molecular mass:
    185872 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CROCC2 Gene

Post-translational modifications for CROCC2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CROCC2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CROCC2 Gene

Domains & Families for CROCC2 Gene

Gene Families for CROCC2 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CROCC2 Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the rootletin family.
  • Belongs to the rootletin family.
genes like me logo Genes that share domains with CROCC2: view

No data available for Suggested Antigen Peptide Sequences for CROCC2 Gene

Function for CROCC2 Gene

Phenotypes From GWAS Catalog for CROCC2 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CROCC2 Gene

Localization for CROCC2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for CROCC2 Gene

Pathways & Interactions for CROCC2 Gene

SuperPathways for CROCC2 Gene

No Data Available

Interacting Proteins for CROCC2 Gene

Gene Ontology (GO) - Biological Process for CROCC2 Gene


No data available for Pathways by source and SIGNOR curated interactions for CROCC2 Gene

Drugs & Compounds for CROCC2 Gene

No Compound Related Data Available

Transcripts for CROCC2 Gene

mRNA/cDNA for CROCC2 Gene

(2) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for CROCC2 Gene

No ASD Table

Relevant External Links for CROCC2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CROCC2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

NURSA nuclear receptor signaling pathways regulating expression of CROCC2 Gene:

genes like me logo Genes that share expression patterns with CROCC2: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CROCC2 Gene

Orthologs for CROCC2 Gene

This gene was present in the common ancestor of animals.

Orthologs for CROCC2 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 95 (a)
(Rattus norvegicus)
Mammalia LOC102551034 33
  • 74.27 (n)
(Mus musculus)
Mammalia E030010N08Rik 33
  • 70.45 (n)
Crocc2 16
(Bos Taurus)
Mammalia -- 34
  • 43 (a)
(Canis familiaris)
Mammalia -- 34
  • 39 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 26 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 24 (a)
(Gallus gallus)
Aves -- 34
  • 10 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 24 (a)
(Danio rerio)
Actinopterygii si:ch211-95g8.1 34
  • 17 (a)
fruit fly
(Drosophila melanogaster)
Insecta Rootletin 34
  • 9 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 15 (a)
Species where no ortholog for CROCC2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CROCC2 Gene

Gene Tree for CROCC2 (if available)
Gene Tree for CROCC2 (if available)
Evolutionary constrained regions (ECRs) for CROCC2: view image

Paralogs for CROCC2 Gene

Paralogs for CROCC2 Gene

genes like me logo Genes that share paralogs with CROCC2: view

Variants for CROCC2 Gene

Sequence variations from dbSNP and Humsavar for CROCC2 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000003547 -- 240,919,642(+) C/T intron_variant
rs1000116147 -- 240,925,923(+) T/A intron_variant
rs1000118795 -- 240,968,573(+) G/C intron_variant
rs1000131271 -- 240,933,587(+) C/T intron_variant
rs1000168335 -- 240,982,803(+) C/T intron_variant

Additional Variant Information for CROCC2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for CROCC2 Gene

Disorders for CROCC2 Gene

Additional Disease Information for CROCC2

No disorders were found for CROCC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CROCC2 Gene

Publications for CROCC2 Gene

  1. Pinstripe: a suite of programs for integrating transcriptomic and proteomic datasets identifies novel proteins and improves differentiation of protein-coding and non-coding genes. (PMID: 23044541) Gascoigne DK … Mattick JS (Bioinformatics (Oxford, England) 2012) 2 3 58
  2. A quantitative atlas of mitotic phosphorylation. (PMID: 18669648) Dephoure N … Gygi SP (Proceedings of the National Academy of Sciences of the United States of America 2008) 4 58
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier LW … Wilson RK (Nature 2005) 4 58
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo MF … Soares MB (Genome research 1996) 3 58

Products for CROCC2 Gene

Sources for CROCC2 Gene

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