Aliases for CROCC Gene
External Ids for CROCC Gene
Previous GeneCards Identifiers for CROCC Gene
GeneCards Summary for CROCC Gene
CROCC (Ciliary Rootlet Coiled-Coil, Rootletin) is a Protein Coding gene. Diseases associated with CROCC include Cellular Ependymoma and Alstrom Syndrome. Gene Ontology (GO) annotations related to this gene include structural molecule activity and kinesin binding. An important paralog of this gene is CROCC2.
UniProtKB/Swiss-Prot Summary for CROCC Gene
Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus (By similarity). Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (PubMed:27623382). Contributes to centrosome cohesion before mitosis (PubMed:16203858).