Aliases for CRISP3 Gene
External Ids for CRISP3 Gene
Previous GeneCards Identifiers for CRISP3 Gene
This gene encodes a member of the cysteine-rich secretory protein (CRISP) family within the CRISP, antigen 5 and pathogenesis-related 1 proteins superfamily. The encoded protein has an N-terminal CRISP, antigen 5 and pathogenesis-related 1 proteins domain, a hinge region, and a C-terminal ion channel regulator domain. This protein contains cysteine residues, located in both the N- and C-terminal domains, that form eight disulfide bonds, a distinguishing characteristic of this family. This gene is expressed in the male reproductive tract where it plays a role in sperm function and fertilization, and the female reproductive tract where it plays a role in endometrial receptivity for embryo implantation. This gene is upregulated in certain types of prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]
GeneCards Summary for CRISP3 Gene
CRISP3 (Cysteine Rich Secretory Protein 3) is a Protein Coding gene. Diseases associated with CRISP3 include Prostate Cancer and Fanconi Anemia, Complementation Group I. Among its related pathways are Innate Immune System. An important paralog of this gene is CRISP2.