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CREG2 (Cellular Repressor Of E1A Stimulated Genes 2) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include oxidoreductase activity and FMN binding. An important paralog of this gene is CREG1.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH02J101387 | Promoter/Enhancer | 1.7 | EPDnew Ensembl ENCODE CraniofacialAtlas | 264.7 | +0.7 | 669 | 1.8 | CTCF ZBTB7B ELF1 SIN3A MAX REST GABPB1 YY1 SMC3 FOSL1 | CREG2 HSALNG0017372 RNF149 | |
GH02J101395 | Promoter/Enhancer | 1.2 | EPDnew Ensembl ENCODE | 259.5 | -11.2 | -11231 | 8 | EP300 FOSL1 RAD21 USF2 CTCF SPI1 NFE2 BATF SMARCE1 EHMT2 | CREG2 RNF149 SNORD89 RFX8 HSALNG0017373 HSALNG0017374 | |
GH02J101388 | Enhancer | 0.5 | ENCODE | 256.9 | -0.5 | -524 | 0.2 | CEBPB MAX FOSL1 JUND NCOA3 FOS | CREG2 HSALNG0017372 HSALNG0017373 RFX8 | |
GH02J101380 | Enhancer | 0.5 | Ensembl | 17.9 | +6.7 | 6670 | 2.2 | JUND FOSL1 MYC MAX EGR1 DACH1 ATF3 | CREG2 SNORD89 ENSG00000226058 HSALNG0017372 RNF149 | |
GH02J101355 | Enhancer | 1 | FANTOM5 Ensembl ENCODE | 7.4 | +31.8 | 31806 | 3.3 | CEBPB ELK1 MAX EP300 POLR2A TBP TCF7L2 ZNF217 MAFF DPF2 | HSALNG0017369 HSALNG0017370 SNORD89 CREG2 RF00017-3285 RNF149 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO:0005615 | extracellular space | IBA | 21873635 |
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005794 | Golgi apparatus | IEA | -- |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CREG2 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CREG2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CREG2 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Creg2 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Creg2 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | CREG2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | CREG2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CREG2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | creg2 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | creg2 30 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | CREG 31 |
|
OneToMany | |
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT2G04690 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os06g0238300 30 |
|
SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11554173 | - |
p.Pro96Gln |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1978n106 | CNV | deletion | 24896259 |
esv1298629 | CNV | deletion | 17803354 |
esv2147665 | CNV | deletion | 18987734 |
esv2423576 | CNV | deletion | 19546169 |
esv2720447 | CNV | deletion | 23290073 |
esv2843014 | CNV | deletion | 24192839 |
esv34123 | CNV | loss | 18971310 |
esv3559855 | CNV | deletion | 23714750 |
esv3591766 | CNV | loss | 21293372 |
esv3892993 | CNV | gain | 25118596 |
esv4768 | CNV | loss | 18987735 |
esv8755 | CNV | loss | 19470904 |
nsv1072427 | CNV | deletion | 25765185 |
nsv1150183 | CNV | deletion | 26484159 |
nsv511800 | CNV | loss | 21212237 |
nsv954719 | CNV | deletion | 24416366 |
nsv961464 | CNV | duplication | 23825009 |
No disorders were found for CREG2 Gene.