Aliases for CREB5 Gene
External Ids for CREB5 Gene
Previous GeneCards Identifiers for CREB5 Gene
The product of this gene belongs to the CRE (cAMP response element)-binding protein family. Members of this family contain zinc-finger and bZIP DNA-binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c-Jun or CRE-BP1, and functions as a CRE-dependent trans-activator. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for CREB5 Gene
CREB5 (CAMP Responsive Element Binding Protein 5) is a Protein Coding gene. Diseases associated with CREB5 include Trichuriasis and Amphetamine Abuse. Among its related pathways are cGMP-PKG signaling pathway and MFAP5-mediated ovarian cancer cell motility and invasiveness. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and sequence-specific DNA binding. An important paralog of this gene is ATF7.
UniProtKB/Swiss-Prot Summary for CREB5 Gene
Binds to the cAMP response element and activates transcription.