This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been ... See more...

Aliases for CREB3L2 Gene

Aliases for CREB3L2 Gene

  • CAMP Responsive Element Binding Protein 3 Like 2 2 3 5
  • BBF2H7 2 3 4
  • Cyclic AMP-Responsive Element-Binding Protein 3-Like Protein 2 3 4
  • CAMP-Responsive Element-Binding Protein 3-Like Protein 2 3 4
  • BBF2 Human Homolog On Chromosome 7 3 4
  • TCAG_1951439 2 3
  • Basic Transcription Factor 2 3
  • B-ZIB Transcription Factor 3
  • FUS/BBF2H7 Protein 3
  • CREB3L2 5

External Ids for CREB3L2 Gene

Previous GeneCards Identifiers for CREB3L2 Gene

  • GC07M136981
  • GC07M136975
  • GC07M137021
  • GC07M137210
  • GC07M137559
  • GC07M131867

Summaries for CREB3L2 Gene

Entrez Gene Summary for CREB3L2 Gene

  • This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

GeneCards Summary for CREB3L2 Gene

CREB3L2 (CAMP Responsive Element Binding Protein 3 Like 2) is a Protein Coding gene. Diseases associated with CREB3L2 include Myxofibrosarcoma and Sarcoma. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and AKT Siganaling Pathway. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is CREB3L1.

UniProtKB/Swiss-Prot Summary for CREB3L2 Gene

  • Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CREB3L2 Gene

Genomics for CREB3L2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CREB3L2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07J137995 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 613.2 +2.5 2501 7.6 SP1 HNRNPL CREB1 GATAD2A CTCF ATF7 TEAD4 PRDM10 REST ZNF629 CREB3L2 TRIM24 AKR1D1 RF00017-6664 lnc-AKR1D1-3 DGKI
GH07J137974 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 13.2 +17.3 17279 21 SP1 GATAD2A ATF7 PRDM10 TFE3 ZNF512 LEF1 IKZF1 NFKBIZ RCOR2 lnc-DGKI-1 TRIM24 CREB3L2 CREB3L2-AS1 RF00017-6664 DGKI
GH07J137889 Enhancer 1.1 Ensembl ENCODE dbSUPER 18.8 +111.3 111260 2.4 CREB1 GATAD2A ZNF629 PKNOX1 EED SOX13 MTA3 RUNX3 FOXA1 NFE2 RF00017-6663 CREB3L2 DGKI piR-48772-030
GH07J137961 Enhancer 1.4 FANTOM5 ENCODE dbSUPER 13.9 +37.0 37039 7.6 GATAD2A ATF7 RFX1 LEF1 IKZF1 RCOR2 BACH1 JUND FOXA1 DDX20 CREB3L2 AKR1D1 TRIM24 CREB3L2-AS1 lnc-DGKI-1 DGKI
GH07J137947 Promoter/Enhancer 1.7 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.2 +48.7 48685 12.7 CREB1 GATAD2A ZNF629 TFE3 RFX1 LEF1 SOX13 IKZF1 NFKBIZ TARDBP CREB3L2-AS1 AKR1D1 CREB3L2 lnc-DGKI-1 DGKI
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CREB3L2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CREB3L2

Top Transcription factor binding sites by QIAGEN in the CREB3L2 gene promoter:
  • AML1a
  • ATF
  • c-Rel
  • CP2
  • E47
  • LyF-1
  • p300
  • Pax-4a
  • Tal-1beta

Genomic Locations for CREB3L2 Gene

Genomic Locations for CREB3L2 Gene
chr7:137,874,979-138,002,086
(GRCh38/hg38)
Size:
127,108 bases
Orientation:
Minus strand
chr7:137,559,725-137,686,846
(GRCh37/hg19)
Size:
127,122 bases
Orientation:
Minus strand

Genomic View for CREB3L2 Gene

Genes around CREB3L2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CREB3L2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CREB3L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CREB3L2 Gene

Proteins for CREB3L2 Gene

  • Protein details for CREB3L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q70SY1-CR3L2_HUMAN
    Recommended name:
    Cyclic AMP-responsive element-binding protein 3-like protein 2
    Protein Accession:
    Q70SY1
    Secondary Accessions:
    • Q6P454
    • Q6ZMR6

    Protein attributes for CREB3L2 Gene

    Size:
    520 amino acids
    Molecular mass:
    57415 Da
    Quaternary structure:
    • Binds DNA as a dimer.

    Alternative splice isoforms for CREB3L2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CREB3L2 Gene

Post-translational modifications for CREB3L2 Gene

  • Upon ER stress, translocated to the Golgi apparatus, where it is processed by regulated intramembrane proteolysis (RIP) to release the cytosol-facing N-terminal transcription factor domain. The cleavage is performed sequentially by site-1 and site-2 proteases (S1P/MBTPS1 and S2P/MBTPS2).
  • N-glycosylated.
  • Ubiquitinated by HRD1/SYVN1; undergoes 'Lys-48'-linked ubiquitination, followed by rapid proteasomal degradation under normal conditions. Upon ER stress, SYVN1 E3 ubiquitin-protein ligase dissociates from its substrate, ubiquitination does not occur and CREB3L2 is stabilized.
  • Glycosylation at Asn480, Asn504, and Asn517
  • Ubiquitination at Lys364
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for CREB3L2 Gene

Domains & Families for CREB3L2 Gene

Gene Families for CREB3L2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Predicted intracellular proteins
  • Predicted membrane proteins
  • Transcription factors

Protein Domains for CREB3L2 Gene

InterPro:
Blocks:
  • bZIP transcription factor, bZIP_1
ProtoNet:

Suggested Antigen Peptide Sequences for CREB3L2 Gene

GenScript: Design optimal peptide antigens:
  • CREB3L2 protein (A2RRN1_HUMAN)
  • BBF2 human homolog on chromosome 7 (CR3L2_HUMAN)
  • CREB3L2 protein (Q86VD4_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q70SY1

UniProtKB/Swiss-Prot:

CR3L2_HUMAN :
  • Belongs to the bZIP family. ATF subfamily.
Family:
  • Belongs to the bZIP family. ATF subfamily.
genes like me logo Genes that share domains with CREB3L2: view

Function for CREB3L2 Gene

Molecular function for CREB3L2 Gene

UniProtKB/Swiss-Prot Function:
Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827).
UniProtKB/Swiss-Prot Induction:
Up-regulated by ER stress at the transcript and protein levels, the increase at the protein level is much higher than at the transcript level. This induction is accompanied by increased proteolytic cleavage that releases the N-terminal transcription factor domain.

Phenotypes From GWAS Catalog for CREB3L2 Gene

Gene Ontology (GO) - Molecular Function for CREB3L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000976 transcription regulatory region sequence-specific DNA binding IMP 17178827
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA --
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific ISM 19274049
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific IEA --
GO:0003677 DNA binding IEA --
genes like me logo Genes that share ontologies with CREB3L2: view
genes like me logo Genes that share phenotypes with CREB3L2: view

Animal Models for CREB3L2 Gene

MGI Knock Outs for CREB3L2:

Animal Model Products

CRISPR Products

miRNA for CREB3L2 Gene

miRTarBase miRNAs that target CREB3L2

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CREB3L2

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CREB3L2 Gene

Localization for CREB3L2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CREB3L2 Gene

Endoplasmic reticulum membrane. Single-pass type II membrane protein. Note=ER membrane resident protein. Upon ER stress, translocated to the Golgi apparatus where it is cleaved. The cytosolic N-terminal fragment (processed cyclic AMP-responsive element-binding protein 3-like protein 1) is transported into the nucleus. {ECO:0000250 UniProtKB:Q8BH52}.
[Processed cyclic AMP-responsive element-binding protein 3-like protein 2]: Nucleus. Note=Upon ER stress, translocated into the nucleus. {ECO:0000250 UniProtKB:Q8BH52}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CREB3L2 gene
Compartment Confidence
nucleus 5
endoplasmic reticulum 5
golgi apparatus 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endosome 1
cytosol 1
lysosome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Nucleoplasm (3)
  • Endoplasmic reticulum (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CREB3L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000785 chromatin IEA --
GO:0000790 nuclear chromatin ISA --
GO:0005634 nucleus IEA,IDA 17178827
GO:0005654 nucleoplasm IDA --
GO:0005783 endoplasmic reticulum IDA 17178827
genes like me logo Genes that share ontologies with CREB3L2: view

Pathways & Interactions for CREB3L2 Gene

genes like me logo Genes that share pathways with CREB3L2: view

SIGNOR curated interactions for CREB3L2 Gene

Is activated by:

Gene Ontology (GO) - Biological Process for CREB3L2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002062 chondrocyte differentiation ISS --
GO:0006355 regulation of transcription, DNA-templated IEA --
GO:0006888 ER to Golgi vesicle-mediated transport IEA --
GO:0006986 response to unfolded protein IEA --
GO:0007275 multicellular organism development IEA --
genes like me logo Genes that share ontologies with CREB3L2: view

Drugs & Compounds for CREB3L2 Gene

(1) Drugs for CREB3L2 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
cyclic amp Experimental Pharma 0
genes like me logo Genes that share compounds with CREB3L2: view

Transcripts for CREB3L2 Gene

mRNA/cDNA for CREB3L2 Gene

3 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
8 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CREB3L2

Alternative Splicing Database (ASD) splice patterns (SP) for CREB3L2 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14a · 14b
SP1: - - - - -
SP2: - -
SP3: - - - -
SP4:
SP5: - - -
SP6: - - - -

Relevant External Links for CREB3L2 Gene

GeneLoc Exon Structure for
CREB3L2

Expression for CREB3L2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CREB3L2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CREB3L2 Gene

This gene is overexpressed in Fetal Liver (51.4) and Placenta (17.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CREB3L2 Gene



Protein tissue co-expression partners for CREB3L2 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CREB3L2

SOURCE GeneReport for Unigene cluster for CREB3L2 Gene:

Hs.490273

mRNA Expression by UniProt/SwissProt for CREB3L2 Gene:

Q70SY1-CR3L2_HUMAN
Tissue specificity: Widely expressed with highest levels in placenta, lung, spleen and intestine, and lowest levels in heart, brain, skeletal muscle, thymus, colon and leukocytes. In fetal tissues, the weakest expression is detected in brain and heart.

Evidence on tissue expression from TISSUES for CREB3L2 Gene

  • Nervous system(4.5)
  • Skin(4.4)
  • Lung(4.4)
  • Thyroid gland(2.6)
  • Kidney(2.3)
  • Liver(2.2)
  • Heart(2.2)
  • Intestine(2.2)
  • Pancreas(2.1)
  • Muscle(2.1)
  • Spleen(2)
genes like me logo Genes that share expression patterns with CREB3L2: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CREB3L2 Gene

Orthologs for CREB3L2 Gene

This gene was present in the common ancestor of animals.

Orthologs for CREB3L2 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CREB3L2 30 31
  • 99.04 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CREB3L2 31
  • 95 (a)
OneToOne
LOC491369 30
  • 90.19 (n)
Cow
(Bos Taurus)
Mammalia CREB3L2 30 31
  • 89.81 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Creb3l2 30
  • 87.24 (n)
Mouse
(Mus musculus)
Mammalia Creb3l2 30 17 31
  • 87.05 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia CREB3L2 31
  • 71 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CREB3L2 31
  • 62 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CREB3L2 30 31
  • 70.74 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CREB3L2 31
  • 65 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia creb3l2 30
  • 61.92 (n)
Zebrafish
(Danio rerio)
Actinopterygii creb3l2 30 31
  • 60.44 (n)
OneToOne
Fruit Fly
(Drosophila melanogaster)
Insecta CrebA 31
  • 23 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea crh-2 31
  • 25 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.6977 31
  • 26 (a)
OneToMany
Species where no ortholog for CREB3L2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for CREB3L2 Gene

ENSEMBL:
Gene Tree for CREB3L2 (if available)
TreeFam:
Gene Tree for CREB3L2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CREB3L2: view image

Paralogs for CREB3L2 Gene

Paralogs for CREB3L2 Gene

(2) SIMAP similar genes for CREB3L2 Gene using alignment to 5 proteins:

  • CR3L2_HUMAN
  • A2RRN1_HUMAN
  • C9JPH0_HUMAN
  • H7C1W8_HUMAN
  • Q86VD4_HUMAN
genes like me logo Genes that share paralogs with CREB3L2: view

Variants for CREB3L2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CREB3L2 Gene

SNP ID Clinical significance and condition Chr 07 pos Variation AA Info Type
rs273957 - p.Val130Ile

Additional dbSNP identifiers (rs#s) for CREB3L2 Gene

Structural Variations from Database of Genomic Variants (DGV) for CREB3L2 Gene

Variant ID Type Subtype PubMed ID
dgv11621n54 CNV loss 21841781
esv2595133 CNV deletion 19546169
esv2675854 CNV deletion 23128226
esv2735211 CNV deletion 23290073
esv28034 CNV loss 19812545
esv33947 CNV gain 17666407
esv3542496 CNV deletion 23714750
esv3542497 CNV deletion 23714750
esv3572163 CNV loss 25503493
esv3615180 CNV loss 21293372
nsv1022793 CNV gain 25217958
nsv1124271 CNV deletion 24896259
nsv1132088 CNV deletion 24896259
nsv518070 CNV gain 19592680
nsv5963 CNV insertion 18451855
nsv5964 CNV deletion 18451855
nsv608470 CNV loss 21841781
nsv831150 CNV gain+loss 17160897

Variation tolerance for CREB3L2 Gene

Residual Variation Intolerance Score: 52% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.92; 35.70% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CREB3L2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CREB3L2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CREB3L2 Gene

Disorders for CREB3L2 Gene

MalaCards: The human disease database

(8) MalaCards diseases for CREB3L2 Gene - From: Orphanet, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
myxofibrosarcoma
  • fibromyxoid sarcoma
sarcoma
  • connective and soft tissue neoplasm
kidney fibrosarcoma
  • fibrosarcoma of the kidney
isolated growth hormone deficiency, type ii
  • ighd2
adult fibrosarcoma
- elite association - COSMIC cancer census association via MalaCards

UniProtKB/Swiss-Prot

CR3L2_HUMAN
  • Note=A chromosomal aberration involving CREB3L2 is found in low grade fibromyxoid sarcoma (LGFMS). Translocation t(7;16)(q33;p11) with FUS.

Additional Disease Information for CREB3L2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CREB3L2: view

No data available for Genatlas for CREB3L2 Gene

Publications for CREB3L2 Gene

  1. BBF2H7, a novel transmembrane bZIP transcription factor, is a new type of endoplasmic reticulum stress transducer. (PMID: 17178827) Kondo S … Imaizumi K (Molecular and cellular biology 2007) 3 4 23
  2. Fusion of the FUS and BBF2H7 genes in low grade fibromyxoid sarcoma. (PMID: 12915480) Storlazzi CT … Panagopoulos I (Human molecular genetics 2003) 3 4 23
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
  4. Characterization of the native CREB3L2 transcription factor and the FUS/CREB3L2 chimera. (PMID: 17117415) Panagopoulos I … Mertens F (Genes, chromosomes & cancer 2007) 3 23
  5. The chimeric FUS/CREB3l2 gene is specific for low-grade fibromyxoid sarcoma. (PMID: 15139001) Panagopoulos I … Mertens F (Genes, chromosomes & cancer 2004) 4 23

Products for CREB3L2 Gene

Sources for CREB3L2 Gene