Aliases for CRABP1 Gene
External Ids for CRABP1 Gene
Previous HGNC Symbols for CRABP1 Gene
Previous GeneCards Identifiers for CRABP1 Gene
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008]
GeneCards Summary for CRABP1 Gene
CRABP1 (Cellular Retinoic Acid Binding Protein 1) is a Protein Coding gene. Diseases associated with CRABP1 include Teratocarcinoma and Embryonal Carcinoma. Among its related pathways are Drug metabolism - cytochrome P450 and Vitamin A and Carotenoid Metabolism. Gene Ontology (GO) annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP2.
UniProtKB/Swiss-Prot for CRABP1 Gene
Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.