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Aliases for CPSF2 Gene
Aliases for CPSF2 Gene
- Cleavage And Polyadenylation Specific Factor 2 2 3 5
- Cleavage And Polyadenylation Specificity Factor 100 KDa Subunit 3 4
- Cleavage And Polyadenylation Specificity Factor Subunit 2 3 4
- Cleavage And Polyadenylation Specific Factor 2, 100kDa 2 3
- CPSF 100 KDa Subunit 3 4
- CPSF100 3 4
- Cleavage And Polyadenylation Specific Factor 2, 100kD Subunit 2
- CPSF 100kDa Subunit 3
- KIAA1367 4
External Ids for CPSF2 Gene
- HGNC: 2325
- Entrez Gene: 53981
- Ensembl: ENSG00000165934
- OMIM: 606028
- UniProtKB: Q9P2I0
Previous GeneCards Identifiers for CPSF2 Gene
- GC14P090094
- GC14P086404
- GC14P090578
- GC14P091658
- GC14P092588
- GC14P072769
Summaries for CPSF2 Gene
GeneCards Summary for CPSF2 Gene
CPSF2 (Cleavage And Polyadenylation Specific Factor 2) is a Protein Coding gene. Among its related pathways are Transport of Mature Transcript to Cytoplasm and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is CPSF3.
UniProtKB/Swiss-Prot Summary for CPSF2 Gene
-
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Additional gene information for CPSF2 Gene
- Monarch Initiative
- Search for CPSF2 at DataMed
- Search for CPSF2 at HumanCyc
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CPSF2 Gene
Genomics for CPSF2 Gene
GeneHancer (GH) Regulatory Elements for CPSF2 Gene
Promoters and enhancers for CPSF2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CPSF2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CPSF2 gene promoter:
-
- TBP
- TFIID
Genomic Locations for CPSF2 Gene
Genomic Locations for CPSF2 Gene
- chr14:92,121,937-92,172,145
- (GRCh38/hg38)
- Size:
- 50,209 bases
- Orientation:
- Plus strand
- chr14:92,588,281-92,630,755
- (GRCh37/hg19)
- Size:
- 42,475 bases
- Orientation:
- Plus strand
Genomic View for CPSF2 Gene
Genes around CPSF2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by HGNC
- 14q32.12 by Entrez Gene
- 14q32.12 by Ensembl
CPSF2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CPSF2 Gene
Proteins for CPSF2 Gene
-
Protein details for CPSF2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P2I0-CPSF2_HUMAN
- Recommended name:
- Cleavage and polyadenylation specificity factor subunit 2
- Protein Accession:
- Q9P2I0
- B3KME1
- Q6NSJ1
- Q9H3W7
Protein attributes for CPSF2 Gene
- Size:
- 782 amino acids
- Molecular mass:
- 88487 Da
- Quaternary structure:
-
- Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with CPSF3, CSTF2 and SYMPK. Interacts with ZC3H3 (By similarity).
Protein Expression for CPSF2 Gene
Post-translational modifications for CPSF2 Gene
Other Protein References for CPSF2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-CPSF2 Antibody
- Creative Diagnostics Anti-CPSF2 monoclonal antibody
- Alomone Labs, Ltd. Anti-LPAR2 (EDG4) (extracellular)-FITC Antibody
-
Custom Antibody ServicesOriGene Antibodies for CPSF2
- Novus Biologicals Antibodies for CPSF2
-
Abcam antibodies for CPSF2
- Invitrogen Antibodies for CPSF2 (AFLGC-CPSF2)
-
Santa Cruz Biotechnology (SCBT) Antibodies for CPSF2
Protein Products
- Creative Biomart Recombinant Human CPSF2 293 Cell Lysate
-
OriGene Purified Proteins for CPSF2
- Search Origene for MassSpec and Protein Over-expression Lysates for CPSF2
- Origene Custom Protein Services for CPSF2
- antibodies-online: Show 5 available CPSF2 Proteins ranked by validation data
- Compare Top CPSF2 Proteins
-
Quality Products:
-
Abcam proteins for CPSF2
No data available for DME Specific Peptides for CPSF2 Gene
Domains & Families for CPSF2 Gene
Gene Families for CPSF2 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CPSF2 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CPSF2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ11050 fis, clone PLACE1004564, highly similar to Cleavage and polyadenylation specificity factor 100 kDa subunit (B3KMI0_HUMAN)
- Cleavage and polyadenylation specificity factor 100 kDa subunit (CPSF2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9P2I0UniProtKB/Swiss-Prot:
CPSF2_HUMAN :- Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
- Family:
-
- Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
Function for CPSF2 Gene
Molecular function for CPSF2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.
Phenotypes From GWAS Catalog for CPSF2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 18288197 |
Phenotypes for CPSF2 Gene
- GenomeRNAi human phenotypes for CPSF2:
-
- Increased shRNA abundance (Z-score > 2)
- G0/1 arrest
- Decreased cell number
- Increased cell size
- Reduced mammosphere formation
- Decreased viability in esophageal squamous lineage
- Decreased viability
- no effect
- Synthetic lethal with Ras
- Decreased NF-kappaB reporter expression
- Decreased shRNA abundance (Z-score < -2)
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for CPSF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- Applied Biological Materials (abm): CRISPR Clones for CPSF2 - Select products 50% OFF >
- * CPSF2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * CPSF2 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
miRNA for CPSF2 Gene
- miRTarBase miRNAs that target CPSF2
-
- hsa-mir-193a-3p (MIRT044892)
- hsa-mir-4436b-3p (MIRT443625)
- hsa-mir-4480 (MIRT443626)
- hsa-mir-3185 (MIRT443627)
- hsa-mir-873-5p (MIRT443628)
- hsa-mir-761 (MIRT443629)
- hsa-mir-3619-5p (MIRT443630)
- hsa-mir-214-3p (MIRT443631)
- hsa-mir-6165 (MIRT443632)
- hsa-mir-6513-5p (MIRT677288)
- hsa-mir-887-5p (MIRT677289)
- hsa-mir-3913-5p (MIRT677290)
- hsa-mir-3122 (MIRT677291)
- hsa-mir-450a-1-3p (MIRT677292)
- hsa-mir-6780a-5p (MIRT677293)
- hsa-mir-6779-5p (MIRT677294)
- hsa-mir-3689c (MIRT677295)
- hsa-mir-3689b-3p (MIRT677296)
- hsa-mir-3689a-3p (MIRT677297)
- hsa-mir-30b-3p (MIRT677298)
- hsa-mir-1273h-5p (MIRT677299)
- hsa-mir-6788-5p (MIRT677300)
- hsa-mir-30c-2-3p (MIRT677301)
- hsa-mir-30c-1-3p (MIRT677302)
- hsa-mir-7977 (MIRT677303)
- hsa-mir-6799-5p (MIRT677304)
- hsa-mir-6883-5p (MIRT677305)
- hsa-mir-6785-5p (MIRT677306)
- hsa-mir-4728-5p (MIRT677307)
- hsa-mir-149-3p (MIRT677308)
- hsa-mir-7106-5p (MIRT677309)
- hsa-mir-24-3p (MIRT677310)
- hsa-mir-4284 (MIRT677311)
- hsa-mir-5008-5p (MIRT677312)
- hsa-mir-5693 (MIRT677313)
- hsa-mir-3937 (MIRT677314)
- hsa-mir-383-3p (MIRT677315)
- hsa-mir-4519 (MIRT677316)
- hsa-mir-26b-5p (MIRT727940)
- hsa-mir-26a-5p (MIRT727941)
- hsa-mir-4767 (MIRT786664)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for CPSF2
- Browse OriGene Inhibitory RNA Products For CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CPSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- Applied Biological Materials (abm): Clones for CPSF2 - Select products 50% OFF >
- * CPSF2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * CPSF2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CPSF2 Gene
Localization for CPSF2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CPSF2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 0 |
| cytosol | 0 |
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex | IDA,IEA | 18305108 |
| GO:0016020 | membrane | HDA | 19946888 |
Pathways & Interactions for CPSF2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
.41
|
| 2 | Cleavage of Growing Transcript in the Termination Region | ||
| 3 | Processing of Capped Intronless Pre-mRNA | ||
| 4 | Transport of the SLBP independent Mature mRNA | ||
| 5 | mRNA surveillance pathway | ||
Pathways by source for CPSF2 Gene
1 BioSystems pathway for CPSF2 Gene
13 Reactome pathways for CPSF2 Gene
1 KEGG pathway for CPSF2 Gene
Interacting Proteins for CPSF2 Gene
Selected Interacting proteins:
Q9P2I0-CPSF2_HUMAN
ENSP00000298875
for CPSF2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for CPSF2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006369 | termination of RNA polymerase II transcription | TAS | -- |
| GO:0006378 | mRNA polyadenylation | IEA | -- |
| GO:0006379 | mRNA cleavage | IEA | -- |
| GO:0006397 | mRNA processing | IEA | -- |
No data available for SIGNOR curated interactions for CPSF2 Gene
Drugs & Compounds for CPSF2 Gene
No Compound Related Data Available
Drug Products
- Creative Biomart Recombinant Human CPSF2 293 Cell Lysate
Transcripts for CPSF2 Gene
mRNA/cDNA for CPSF2 Gene
- (4) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (168) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000298875 13035 bps (ENST00000298875.8)
- ENST00000553427 715 bps (ENST00000553427.5)
- ENST00000554290 558 bps (ENST00000554290.1)
- ENST00000556622 469 bps (ENST00000556622.1)
- ENST00000555244 806 bps (ENST00000555244.1)
CRISPR Products
-
OriGene CRISPR knockouts for CPSF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- Applied Biological Materials (abm): CRISPR Clones for CPSF2 - Select products 50% OFF >
- * CPSF2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * CPSF2 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for CPSF2
- Browse OriGene Inhibitory RNA Products For CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CPSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- Applied Biological Materials (abm): Clones for CPSF2 - Select products 50% OFF >
- * CPSF2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * CPSF2 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP3: |
Expression for CPSF2 Gene
This gene is overexpressed in Lymph node (14.2), Peripheral blood mononuclear cells (6.7), and Bone (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CPSF2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CPSF2 Gene:
CPSF2SOURCE GeneReport for Unigene cluster for CPSF2 Gene:
Hs.657632Evidence on tissue expression from TISSUES for CPSF2 Gene
- Nervous system(4.6)
- Liver(4.3)
- Lymph node(4.2)
- Stomach(2.3)
Primer Products
-
OriGene qPCR primer pairs for CPSF2
-
OriGene qPCR primer pairs and template standards for CPSF2
- genomics-online: primer clones - Search results for available CPSF2 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CPSF2 Gene
Orthologs for CPSF2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CPSF2 33 32 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CPSF2 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CPSF2 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CPSF2 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CPSF2 33 32 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Cpsf2 32 |
|
||
| mouse (Mus musculus) |
Mammalia | Cpsf2 17 33 32 |
|
||
| chicken (Gallus gallus) |
Aves | CPSF2 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CPSF2 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cpsf2 32 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | cpsf2-A 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cpsf2 33 32 |
|
OneToOne | |
| Dr.12526 32 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Cpsf100 33 32 |
|
OneToOne | |
| BcDNA:LD14168 34 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002474 32 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | cpsf-2 33 32 |
|
OneToOne | |
| F09G2.4 34 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CFT2 35 33 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CPSF100 32 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os09g0569400 32 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | Cin.13623 32 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.13623 32 |
|
- Species where no ortholog for CPSF2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for CPSF2 Gene
- ENSEMBL:
- Gene Tree for CPSF2 (if available)
- TreeFam:
- Gene Tree for CPSF2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CPSF2: view image
Paralogs for CPSF2 Gene
Variants for CPSF2 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000040093 | -- | 92,157,249(+) | T/C | intron_variant | |
| rs1000066590 | -- | 92,122,001(+) | C/G | 5_prime_UTR_variant | |
| rs1000102024 | -- | 92,146,690(+) | A/G | intron_variant | |
| rs1000218911 | -- | 92,147,770(+) | C/T | intron_variant | |
| rs1000308397 | -- | 92,152,339(+) | G/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1267299 | CNV | insertion | 17803354 |
| esv3635331 | CNV | loss | 21293372 |
| esv999869 | CNV | insertion | 20482838 |
| nsv1397 | CNV | insertion | 18451855 |
| nsv472736 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
12.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.93;
19.22% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CPSF2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CPSF2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CPSF2 Gene
Disorders for CPSF2 Gene
Additional Disease Information for CPSF2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CPSF2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CPSF2 Gene
Publications for CPSF2 Gene
- Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. (PMID: 21546767) Murea M … Freedman BI (American journal of nephrology 2011) 3 43 56
- The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PMID: 20546612) Zhao J … Grant SF (BMC medical genetics 2010) 3 43 56
- The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA. (PMID: 21102410) Laishram RS … Anderson RA (The EMBO journal 2010) 3 4 56
- Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson DF … Stefansson K (Nature genetics 2008) 3 43 56
- Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation. (PMID: 18688255) Kolev NG … Steitz JA (EMBO reports 2008) 3 4 56
ExternalLinks
Products for CPSF2 Gene
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- OriGene qPCR primer pairs for CPSF2
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- antibodies-online: Show 12 available CPSF2 Antibodies ranked by validation data
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- antibodies-online: Show 5 available CPSF2 Proteins ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for CPSF2
- Search Santa Cruz Biotechnology (SCBT) for CPSF2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- genomics-online: primer clones - Search results for available CPSF2 gene related products
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
Sources for CPSF2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource