Aliases for CPSF2 Gene
External Ids for CPSF2 Gene
Previous GeneCards Identifiers for CPSF2 Gene
GeneCards Summary for CPSF2 Gene
CPSF2 (Cleavage And Polyadenylation Specific Factor 2) is a Protein Coding gene. Diseases associated with CPSF2 include Sveinsson Chorioretinal Atrophy. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Tat-mediated elongation of the HIV-1 transcript. Gene Ontology (GO) annotations related to this gene include RNA binding. An important paralog of this gene is INTS11.
UniProtKB/Swiss-Prot Summary for CPSF2 Gene
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3' end pre-mRNA processing.