Aliases for CPSF2 Gene
Aliases for CPSF2 Gene
- Cleavage And Polyadenylation Specific Factor 2 2 3 5
- Cleavage And Polyadenylation Specificity Factor 100 KDa Subunit 3 4
- Cleavage And Polyadenylation Specific Factor 2, 100kDa 2 3
- CPSF 100 KDa Subunit 3 4
- CPSF100 3 4
- Cleavage And Polyadenylation Specific Factor 2, 100kD Subunit 2
- Cleavage And Polyadenylation Specificity Factor Subunit 2 3
- CPSF 100kDa Subunit 3
- KIAA1367 4
External Ids for CPSF2 Gene
- HGNC: 2325
- Entrez Gene: 53981
- Ensembl: ENSG00000165934
- OMIM: 606028
- UniProtKB: Q9P2I0
Previous GeneCards Identifiers for CPSF2 Gene
- GC14P090094
- GC14P086404
- GC14P090578
- GC14P091658
- GC14P092588
- GC14P072769
Summaries for CPSF2 Gene
GeneCards Summary for CPSF2 Gene
CPSF2 (Cleavage And Polyadenylation Specific Factor 2) is a Protein Coding gene. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Transport of the SLBP independent Mature mRNA. Gene Ontology (GO) annotations related to this gene include RNA binding.
UniProtKB/Swiss-Prot for CPSF2 Gene
-
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3 end pre-mRNA processing.
Additional gene information for CPSF2 Gene
- Monarch Initiative
- Search for CPSF2 at DataMed
- Search for CPSF2 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CPSF2 Gene
Genomics for CPSF2 Gene
GeneHancer (GH) Regulatory Elements for CPSF2 Gene
Promoters and enhancers for CPSF2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around CPSF2 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CPSF2 gene promoter:
Regulatory Element Products
Genomic Locations for CPSF2 Gene
Genomic Locations for CPSF2 Gene
- chr14:92,121,937-92,172,145
- (GRCh38/hg38)
- Size:
- 50,209 bases
- Orientation:
- Plus strand
- chr14:92,588,281-92,630,755
- (GRCh37/hg19)
Genomic View for CPSF2 Gene
Genes around CPSF2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by Entrez Gene
- 14q32.12 by HGNC
- 14q32.12 by Ensembl
CPSF2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CPSF2 Gene
Proteins for CPSF2 Gene
-
Protein details for CPSF2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9P2I0-CPSF2_HUMAN
- Recommended name:
- Cleavage and polyadenylation specificity factor subunit 2
- Protein Accession:
- Q9P2I0
- B3KME1
- Q6NSJ1
- Q9H3W7
Protein attributes for CPSF2 Gene
- Size:
- 782 amino acids
- Molecular mass:
- 88487 Da
- Quaternary structure:
-
- Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Interacts with CPSF3, CSTF2 and SYMPK. Interacts with ZC3H3 (By similarity).
Protein Expression for CPSF2 Gene
Post-translational modifications for CPSF2 Gene
Other Protein References for CPSF2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CPSF2
- Novus Biologicals Antibodies for CPSF2
- Invitrogen Antibodies for CPSF2
- GeneTex CPSF2 Antibody for CPSF2
-
Boster Bio Antibodies for CPSF2
-
Santa Cruz Biotechnology (SCBT) Antibodies for CPSF2
Protein Products
-
OriGene Purified Proteins for CPSF2
- Search Origene for MassSpec and Protein Over-expression Lysates for CPSF2
- Origene Custom Protein Services for CPSF2
- antibodies-online: Search results for 5 available CPSF2 Proteins ranked by validation data
- Compare Top CPSF2 Proteins
-
Quality Products:
- Search GeneTex for Proteins for CPSF2
Assay Products
No data available for DME Specific Peptides for CPSF2 Gene
Domains & Families for CPSF2 Gene
Gene Families for CPSF2 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CPSF2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for CPSF2 Gene
Graphical View of Domain Structure for InterPro Entry
Q9P2I0UniProtKB/Swiss-Prot:
CPSF2_HUMAN :- Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
- Family:
-
- Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
Function for CPSF2 Gene
Molecular function for CPSF2 Gene
- UniProtKB/Swiss-Prot Function:
- Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. Involved in the histone 3 end pre-mRNA processing.
Phenotypes From GWAS Catalog for CPSF2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | -- |
| GO:0005515 | protein binding | IPI | 17353931 |
Phenotypes for CPSF2 Gene
- GenomeRNAi human phenotypes for CPSF2:
-
- Increased shRNA abundance (Z-score > 2)
- G0/1 arrest
- Increased G1 DNA content
- Increased cell size
- Reduced mammosphere formation
- Decreased viability in esophageal squamous lineage
- Decreased shRNA abundance (Z-score < -2)
- Decreased viability
- no effect
- Synthetic lethal with Ras
- Decreased NF-kappaB reporter expression
- Increased viability
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CPSF2
-
CRISPR Products
-
OriGene CRISPR knockouts for CPSF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- Applied Biological Materials CRISPR for CPSF2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
- GenScript: Design CRISPR guide RNA sequences for CPSF2
miRNA for CPSF2 Gene
- miRTarBase miRNAs that target CPSF2
-
- hsa-mir-193a-3p (MIRT044892)
- hsa-mir-4436b-3p (MIRT443625)
- hsa-mir-4480 (MIRT443626)
- hsa-mir-3185 (MIRT443627)
- hsa-mir-873-5p (MIRT443628)
- hsa-mir-761 (MIRT443629)
- hsa-mir-3619-5p (MIRT443630)
- hsa-mir-214-3p (MIRT443631)
- hsa-mir-6165 (MIRT443632)
- hsa-mir-6513-5p (MIRT677288)
- hsa-mir-887-5p (MIRT677289)
- hsa-mir-3913-5p (MIRT677290)
- hsa-mir-3122 (MIRT677291)
- hsa-mir-450a-1-3p (MIRT677292)
- hsa-mir-6780a-5p (MIRT677293)
- hsa-mir-6779-5p (MIRT677294)
- hsa-mir-3689c (MIRT677295)
- hsa-mir-3689b-3p (MIRT677296)
- hsa-mir-3689a-3p (MIRT677297)
- hsa-mir-30b-3p (MIRT677298)
- hsa-mir-1273h-5p (MIRT677299)
- hsa-mir-6788-5p (MIRT677300)
- hsa-mir-30c-2-3p (MIRT677301)
- hsa-mir-30c-1-3p (MIRT677302)
- hsa-mir-7977 (MIRT677303)
- hsa-mir-6799-5p (MIRT677304)
- hsa-mir-6883-5p (MIRT677305)
- hsa-mir-6785-5p (MIRT677306)
- hsa-mir-4728-5p (MIRT677307)
- hsa-mir-149-3p (MIRT677308)
- hsa-mir-7106-5p (MIRT677309)
- hsa-mir-24-3p (MIRT677310)
- hsa-mir-4284 (MIRT677311)
- hsa-mir-5008-5p (MIRT677312)
- hsa-mir-5693 (MIRT677313)
- hsa-mir-3937 (MIRT677314)
- hsa-mir-383-3p (MIRT677315)
- hsa-mir-4519 (MIRT677316)
- hsa-mir-26b-5p (MIRT727940)
- hsa-mir-26a-5p (MIRT727941)
- hsa-mir-4767 (MIRT786664)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CPSF2
- Browse OriGene Inhibitory RNA Products For CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CPSF2
- VectorBuilder custom plasmid, inducible vectors for CPSF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CPSF2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- Applied Biological Materials Clones for CPSF2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CPSF2 Gene
Localization for CPSF2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CPSF2 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 1 |
| cytosol | 1 |
- Nucleoplasm (2)
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex | IEA,IDA | 18305108 |
| GO:0016020 | membrane | HDA | 19946888 |
Pathways & Interactions for CPSF2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | mRNA Splicing - Major Pathway |
.79
|
.41
|
| 2 | Cleavage of Growing Transcript in the Termination Region | ||
| 3 | Processing of Capped Intronless Pre-mRNA | ||
| 4 | Transport of the SLBP independent Mature mRNA | ||
| 5 | mRNA surveillance pathway | ||
Pathways by source for CPSF2 Gene
1 BioSystems pathway for CPSF2 Gene
13 Reactome pathways for CPSF2 Gene
1 KEGG pathway for CPSF2 Gene
Interacting Proteins for CPSF2 Gene
Selected Interacting proteins:
Q9P2I0-CPSF2_HUMAN
ENSP00000298875
for CPSF2 Gene via
IID
UniProtKB
MINT
STRING
GPS-Prot Interaction Network for CPSF2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000398 | mRNA splicing, via spliceosome | TAS | -- |
| GO:0006369 | termination of RNA polymerase II transcription | TAS | -- |
| GO:0006378 | mRNA polyadenylation | IEA | -- |
| GO:0006379 | mRNA cleavage | IEA | -- |
| GO:0006397 | mRNA processing | IEA | -- |
No data available for SIGNOR curated interactions for CPSF2 Gene
Transcripts for CPSF2 Gene
mRNA/cDNA for CPSF2 Gene
- (7) Additional mRNA sequences :
- (4) REFSEQ mRNAs :
- (168) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000556622 469 bps (uc059emw.1)
- ENST00000555244 806 bps (uc059emx.1)
- ENST00000554290 558 bps (uc059emv.1)
- ENST00000553427 715 bps (uc059emu.1)
- ENST00000298875 13035 bps (uc001yah.3)
Unigene Clusters for CPSF2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CPSF2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- Applied Biological Materials CRISPR for CPSF2
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
- GenScript: Design CRISPR guide RNA sequences for CPSF2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CPSF2
- Browse OriGene Inhibitory RNA Products For CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CPSF2
- VectorBuilder custom plasmid, inducible vectors for CPSF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CPSF2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- Applied Biological Materials Clones for CPSF2
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP3: |
Expression for CPSF2 Gene
This gene is overexpressed in Lymph node (14.2), Peripheral blood mononuclear cells (6.7), and Bone (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CPSF2 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CPSF2 Gene:
CPSF2SOURCE GeneReport for Unigene cluster for CPSF2 Gene:
Hs.657632Evidence on tissue expression from TISSUES for CPSF2 Gene
- Nervous system(4.6)
- Liver(4.3)
- Lymph node(4.2)
- Stomach(2.3)
Primer Products
-
OriGene qPCR primer pairs and template standards for CPSF2
-
OriGene qPCR primer pairs for CPSF2
- genomics-online: primer clones - Search results for available CPSF2 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CPSF2 Gene
Orthologs for CPSF2 Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CPSF2 34 33 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | CPSF2 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CPSF2 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CPSF2 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CPSF2 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Cpsf2 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cpsf2 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | CPSF2 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CPSF2 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cpsf2 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | cpsf2-A 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cpsf2 34 33 |
|
OneToOne | |
| Dr.12526 33 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | Cpsf100 34 33 |
|
OneToOne | |
| BcDNA:LD14168 35 |
|
|
|||
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002474 33 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | cpsf-2 34 33 |
|
OneToOne | |
| F09G2.4 35 |
|
|
|||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CFT2 36 34 |
|
||
| thale cress (Arabidopsis thaliana) |
eudicotyledons | CPSF100 33 |
|
||
| rice (Oryza sativa) |
Liliopsida | Os09g0569400 33 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | Cin.13623 33 |
|
||
| sea squirt (Ciona intestinalis) |
Ascidiacea | Cin.13623 33 |
|
- Species where no ortholog for CPSF2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for CPSF2 Gene
- ENSEMBL:
- Gene Tree for CPSF2 (if available)
- TreeFam:
- Gene Tree for CPSF2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CPSF2: view image
Paralogs for CPSF2 Gene
No data available for Paralogs for CPSF2 Gene
Variants for CPSF2 Gene
| SNP ID | Clin | Chr 14 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000040093 | -- | 92,157,249(+) | T/C | intron_variant | |
| rs1000066590 | -- | 92,122,001(+) | C/G | 5_prime_UTR_variant | |
| rs1000102024 | -- | 92,146,690(+) | A/G | intron_variant | |
| rs1000218911 | -- | 92,147,770(+) | C/T | intron_variant | |
| rs1000308397 | -- | 92,152,339(+) | G/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1267299 | CNV | insertion | 17803354 |
| esv3635331 | CNV | loss | 21293372 |
| esv999869 | CNV | insertion | 20482838 |
| nsv1397 | CNV | insertion | 18451855 |
| nsv472736 | CNV | novel sequence insertion | 20440878 |
Residual Variation Intolerance Score:
12.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.93;
19.22% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CPSF2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CPSF2
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CPSF2 Gene
Disorders for CPSF2 Gene
Additional Disease Information for CPSF2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CPSF2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CPSF2 Gene
Publications for CPSF2 Gene
- Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes. (PMID: 21546767) Murea M … Freedman BI (American journal of nephrology 2011) 3 44 58
- The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PMID: 20546612) Zhao J … Grant SF (BMC medical genetics 2010) 3 44 58
- The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA. (PMID: 21102410) Laishram RS … Anderson RA (The EMBO journal 2010) 3 4 58
- Many sequence variants affecting diversity of adult human height. (PMID: 18391951) Gudbjartsson DF … Stefansson K (Nature genetics 2008) 3 44 58
- Conserved motifs in both CPSF73 and CPSF100 are required to assemble the active endonuclease for histone mRNA 3'-end maturation. (PMID: 18688255) Kolev NG … Steitz JA (EMBO reports 2008) 3 4 58
Products for CPSF2 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for CPSF2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for CPSF2
- Search Origene for MassSpec and Protein Over-expression Lysates for CPSF2
- Origene Custom Protein Services for CPSF2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CPSF2
- Browse OriGene Inhibitory RNA Products For CPSF2
- OriGene qPCR primer pairs and template standards for CPSF2
- OriGene qPCR primer pairs for CPSF2
- OriGene CRISPR knockouts for CPSF2
- OriGene ORF clones in human for CPSF2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CPSF2
- GenScript: Next-day shipping of latest version cDNA ORF clones for CPSF2 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for CPSF2
- GenScript Custom Assay Services for CPSF2
- GenScript Custom overexpressing Cell Line Services for CPSF2
- GenScript: Design CRISPR guide RNA sequences for CPSF2
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for CPSF2
- Sino Biological Human cDNA Clone for CPSF2
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse Sino Biological ELISA Kits
- Browse Sino Biological ELISA Pair Sets
- Browse Sino Biological CRO Services
- Browse Sino Biological Control Vectors
- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for CPSF2
- Novus Biologicals proteins and lysates for CPSF2
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- VectorBuilder custom plasmid, inducible vectors for CPSF2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CPSF2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 28 available CPSF2 Antibodies ranked by validation data
- Compare Top CPSF2 Antibodies
- antibodies-online: Search results for available CPSF2 related products ranked by validation data
- antibodies-online: Search results for 5 available CPSF2 Proteins ranked by validation data
- Compare Top CPSF2 Proteins
- Quality Products:
- GeneTex CPSF2 Antibody for CPSF2
- Search GeneTex for Proteins for CPSF2
- Santa Cruz Biotechnology (SCBT) Antibodies for CPSF2
- Search Santa Cruz Biotechnology (SCBT) for CPSF2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CPSF2
- genomics-online: cdna clones - Search results for available CPSF2 gene related products
- orf clones - Search results for available CPSF2 gene related products
- genomics-online: gRNA clones - Search results for available CPSF2 gene related products
- genomics-online: primer clones - Search results for available CPSF2 gene related products
- genomics-online: shRNA clones - Search results for available CPSF2 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CPSF2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CPSF2
- GeneCopoeia miRNA 3'UTR Target clone products for CPSF2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF2
- Boster Bio Antibodies for CPSF2
- Browse Boster Bio ELISA Kits
Sources for CPSF2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio