Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[suppl... See more...

Aliases for CPSF1 Gene

Aliases for CPSF1 Gene

  • Cleavage And Polyadenylation Specific Factor 1 2 3 5
  • CPSF160 2 3 4
  • Cleavage And Polyadenylation Specificity Factor 160 KDa Subunit 3 4
  • Cleavage And Polyadenylation Specificity Factor Subunit 1 3 4
  • Cleavage And Polyadenylation Specific Factor 1, 160kDa 2 3
  • CPSF 160 KDa Subunit 3 4
  • Cleavage And Polyadenylation Specific Factor 1, 160kD Subunit 2
  • Polyadenylation Specificity Factor 3
  • HSU37012 3
  • P/Cl.18 3
  • MYP27 3
  • CPSF1 5

External Ids for CPSF1 Gene

Previous GeneCards Identifiers for CPSF1 Gene

  • GC08M143221
  • GC08M145623
  • GC08M145223
  • GC08M145589
  • GC08M145618
  • GC08M140731

Summaries for CPSF1 Gene

Entrez Gene Summary for CPSF1 Gene

  • Cleavage and polyadenylation specificity factor (CPSF) is a multisubunit complex that plays a central role in 3-prime processing of pre-mRNAs. CPSF recognizes the AAUAAA signal in the pre-mRNA and interacts with other proteins to facilitate both RNA cleavage and poly(A) synthesis. CPSF1 is the largest subunit of the CPSF complex (Murthy and Manley, 1995 [PubMed 7590244]).[supplied by OMIM, Mar 2008]

GeneCards Summary for CPSF1 Gene

CPSF1 (Cleavage And Polyadenylation Specific Factor 1) is a Protein Coding gene. Diseases associated with CPSF1 include Myopia 27 and Myopia. Among its related pathways are Processing of Capped Intronless Pre-mRNA and Tat-mediated elongation of the HIV-1 transcript. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and mRNA 3'-UTR binding. An important paralog of this gene is DDB1.

UniProtKB/Swiss-Prot Summary for CPSF1 Gene

  • Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).

Gene Wiki entry for CPSF1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CPSF1 Gene

Genomics for CPSF1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CPSF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CPSF1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CPSF1

Top Transcription factor binding sites by QIAGEN in the CPSF1 gene promoter:
  • AhR
  • Arnt
  • Brachyury
  • c-Ets-1
  • CP2
  • FOXO4
  • GATA-1
  • Lmo2
  • NRSF form 1
  • NRSF form 2

Genomic Locations for CPSF1 Gene

Latest Assembly
chr8:144,393,229-144,409,400
(GRCh38/hg38)
Size:
16,172 bases
Orientation:
Minus strand

Previous Assembly
chr8:145,618,446-145,634,719
(GRCh37/hg19 by Entrez Gene)
Size:
16,274 bases
Orientation:
Minus strand

chr8:145,618,444-145,634,753
(GRCh37/hg19 by Ensembl)
Size:
16,310 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr8(PATCHES):123,834-139,938 (-)

Genomic View for CPSF1 Gene

Genes around CPSF1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CPSF1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CPSF1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CPSF1 Gene

Proteins for CPSF1 Gene

  • Protein details for CPSF1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q10570-CPSF1_HUMAN
    Recommended name:
    Cleavage and polyadenylation specificity factor subunit 1
    Protein Accession:
    Q10570
    Secondary Accessions:
    • Q96AF0

    Protein attributes for CPSF1 Gene

    Size:
    1443 amino acids
    Molecular mass:
    160884 Da
    Quaternary structure:
    • Component of the cleavage and polyadenylation specificity factor (CPSF) complex, composed of CPSF1, CPSF2, CPSF3, CPSF4 and FIP1L1. Found in a complex with CPSF1, FIP1L1 and PAPOLA. Interacts with FIP1L1, TENT2/GLD2 and SRRM1. Interacts with TUT1; the interaction is direct and mediates the recruitment of the CPSF complex on the 3'UTR of selected pre-mRNAs.

    Three dimensional structures from OCA and Proteopedia for CPSF1 Gene

neXtProt entry for CPSF1 Gene

Post-translational modifications for CPSF1 Gene

  • The N-terminus is blocked.
  • Ubiquitination at Lys6, Lys52, Lys116, Lys364, Lys395, Lys809, Lys847, Lys1104, Lys1118, Lys1241, and Lys1421
  • Modification sites at PhosphoSitePlus

Antibodies for research

  • Abcam antibodies for CPSF1

No data available for DME Specific Peptides for CPSF1 Gene

Domains & Families for CPSF1 Gene

Gene Families for CPSF1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for CPSF1 Gene

Suggested Antigen Peptide Sequences for CPSF1 Gene

GenScript: Design optimal peptide antigens:
  • Cleavage and polyadenylation specificity factor 160 kDa subunit (CPSF1_HUMAN)
  • Cleavage and polyadenylation specific factor 1, 160kDa, isoform CRA_a (D3DWL9_HUMAN)
  • Polyadenylation specificity factor (Q9C0J6_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q10570

UniProtKB/Swiss-Prot:

CPSF1_HUMAN :
  • Belongs to the CPSF1 family.
Family:
  • Belongs to the CPSF1 family.
genes like me logo Genes that share domains with CPSF1: view

Function for CPSF1 Gene

Molecular function for CPSF1 Gene

UniProtKB/Swiss-Prot Function:
Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (PubMed:14749727). May play a role in eye morphogenesis and the development of retinal ganglion cell projections to the midbrain (By similarity).

Phenotypes From GWAS Catalog for CPSF1 Gene

Gene Ontology (GO) - Molecular Function for CPSF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA --
GO:0005515 protein binding IEA,IPI 7590244
GO:0019899 enzyme binding IPI 7590244
GO:0035925 mRNA 3'-UTR AU-rich region binding IDA 7590244
genes like me logo Genes that share ontologies with CPSF1: view
genes like me logo Genes that share phenotypes with CPSF1: view

Human Phenotype Ontology for CPSF1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF1

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for CPSF1 Gene

Localization for CPSF1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CPSF1 Gene

Nucleus, nucleoplasm.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CPSF1 gene
Compartment Confidence
nucleus 5
cytosol 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CPSF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA,IBA 21873635
GO:0005654 nucleoplasm TAS --
GO:0005847 mRNA cleavage and polyadenylation specificity factor complex IDA 7590244
genes like me logo Genes that share ontologies with CPSF1: view

Pathways & Interactions for CPSF1 Gene

genes like me logo Genes that share pathways with CPSF1: view

Pathways by source for CPSF1 Gene

Gene Ontology (GO) - Biological Process for CPSF1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000398 mRNA splicing, via spliceosome TAS --
GO:0006369 termination of RNA polymerase II transcription TAS --
GO:0006378 mRNA polyadenylation IBA,IMP 7590244
GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation TAS --
GO:0006397 mRNA processing IEA --
genes like me logo Genes that share ontologies with CPSF1: view

No data available for SIGNOR curated interactions for CPSF1 Gene

Drugs & Compounds for CPSF1 Gene

(1) Drugs for CPSF1 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(1) Additional Compounds for CPSF1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with CPSF1: view

Transcripts for CPSF1 Gene

mRNA/cDNA for CPSF1 Gene

1 REFSEQ mRNAs :
7 NCBI additional mRNA sequence :
14 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CPSF1

Alternative Splicing Database (ASD) splice patterns (SP) for CPSF1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d ^ 11a · 11b ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9: - - -
SP10: -
SP11:
SP12:
SP13:
SP14: - -
SP15:
SP16:
SP17:
SP18:
SP19:
SP20:
SP21: -
SP22:
SP23:
SP24:
SP25:
SP26:
SP27:
SP28:
SP29:
SP30:

ExUns: 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c · 25d · 25e ^ 26 ^ 27 ^ 28 ^ 29a · 29b ^ 30 ^ 31a · 31b ^ 32a · 32b · 32c ^
SP1:
SP2: -
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12: -
SP13:
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SP18:
SP19:
SP20:
SP21:
SP22:
SP23:
SP24:
SP25:
SP26:
SP27: -
SP28:
SP29:
SP30:

ExUns: 33a · 33b ^ 34 ^ 35a · 35b ^ 36a · 36b · 36c ^ 37a · 37b · 37c · 37d · 37e ^ 38 ^ 39 ^ 40a · 40b · 40c ^ 41a · 41b · 41c ^ 42a · 42b ^ 43
SP1:
SP2:
SP3:
SP4: -
SP5:
SP6: -
SP7: - -
SP8: -
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:
SP19:
SP20: -
SP21:
SP22:
SP23:
SP24:
SP25:
SP26: -
SP27:
SP28:
SP29:
SP30:

Relevant External Links for CPSF1 Gene

GeneLoc Exon Structure for
CPSF1

Expression for CPSF1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CPSF1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CPSF1 Gene

This gene is overexpressed in Liver, secretome (18.5), Peripheral blood mononuclear cells (9.7), and Lymph node (6.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CPSF1 Gene



Protein tissue co-expression partners for CPSF1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CPSF1

SOURCE GeneReport for Unigene cluster for CPSF1 Gene:

Hs.493202

mRNA Expression by UniProt/SwissProt for CPSF1 Gene:

Q10570-CPSF1_HUMAN
Tissue specificity: Widely expressed, with high expression in the retina.

Evidence on tissue expression from TISSUES for CPSF1 Gene

  • Pancreas(4.3)
  • Nervous system(3.1)
  • Lung(2.7)
  • Skin(2.4)
  • Blood(2.2)
genes like me logo Genes that share expression patterns with CPSF1: view

Primer products for research

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CPSF1 Gene

Orthologs for CPSF1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CPSF1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CPSF1 29
  • 99.13 (n)
Oppossum
(Monodelphis domestica)
Mammalia CPSF1 30
  • 93 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia CPSF1 29 30
  • 90.39 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CPSF1 29 30
  • 90.12 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Cpsf1 29
  • 87.97 (n)
Mouse
(Mus musculus)
Mammalia Cpsf1 29 16 30
  • 87.65 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CPSF1 30
  • 79 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CPSF1 30
  • 82 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia cpsf1 29
  • 77.32 (n)
Str.15765 29
African clawed frog
(Xenopus laevis)
Amphibia LOC398931 29
Zebrafish
(Danio rerio)
Actinopterygii cpsf1 29 30
  • 72.98 (n)
OneToOne
wufb24c01 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.4617 29
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP011340 29
  • 58.37 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Cpsf160 29 30
  • 52.47 (n)
OneToOne
cpsf 31
  • 45 (a)
Worm
(Caenorhabditis elegans)
Secernentea cpsf-1 29 30
  • 44.28 (n)
OneToOne
Y76B12C.7 31
  • 31 (a)
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes CFT1 30
  • 21 (a)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons CPSF160 29
  • 44.85 (n)
Rice
(Oryza sativa)
Liliopsida Os04g0252200 29
  • 44.61 (n)
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 48 (a)
OneToOne
Species where no ortholog for CPSF1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for CPSF1 Gene

ENSEMBL:
Gene Tree for CPSF1 (if available)
TreeFam:
Gene Tree for CPSF1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CPSF1: view image
Alliance of Genome Resources:
Additional Orthologs for CPSF1

Paralogs for CPSF1 Gene

Paralogs for CPSF1 Gene

(1) SIMAP similar genes for CPSF1 Gene using alignment to 3 proteins:

  • CPSF1_HUMAN
  • D3DWL9_HUMAN
  • E9PIM1_HUMAN

Pseudogenes.org Pseudogenes for CPSF1 Gene

genes like me logo Genes that share paralogs with CPSF1: view

Variants for CPSF1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CPSF1 Gene

SNP ID Clinical significance and condition Chr 08 pos Variation AA Info Type
837526 Pathogenic: not provided 144,398,812(-) CAT/C
NM_013291.3(CPSF1):c.1603_1604del (p.Met535fs)
FRAMESHIFT
916362 Likely Benign: not provided 144,398,065(-) G/A
NM_013291.3(CPSF1):c.1962C>T (p.Pro654=)
SYNONYMOUS
rs1554862601 Pathogenic: Myopia 27 144,394,149(-) C/A
NM_013291.3(CPSF1):c.3823G>T (p.Asp1275Tyr)
MISSENSE_VARIANT,NON_CODING_TRANSCRIPT
rs1586620121 Pathogenic: Myopia 27 144,398,338(-) G/A
NM_013291.3(CPSF1):c.1858C>T (p.Gln620Ter)
NONSENSE
rs782555528 Pathogenic: Myopia 27 144,393,592(-) T/C
NM_013291.3(CPSF1):c.4146-2A>G
SPLICE_ACCEPTOR

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for CPSF1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for CPSF1 Gene

Variant ID Type Subtype PubMed ID
dgv12434n54 CNV loss 21841781
dgv12437n54 CNV loss 21841781
esv2759652 CNV gain+loss 17122850
nsv1124391 CNV deletion 24896259
nsv428208 CNV gain 18775914
nsv470249 CNV loss 18288195
nsv515809 CNV gain+loss 19592680
nsv612934 CNV loss 21841781
nsv824805 CNV gain 20364138
nsv831489 CNV loss 17160897

Variation tolerance for CPSF1 Gene

Residual Variation Intolerance Score: 1.19% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.83; 47.90% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CPSF1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CPSF1
Leiden Open Variation Database (LOVD)
CPSF1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CPSF1 Gene

Disorders for CPSF1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for CPSF1 Gene - From: OMI, CVR, COP, and GCD

Disorder Aliases PubMed IDs
myopia 27
  • myp27
myopia
  • near vision
- elite association - COSMIC cancer census association via MalaCards
Search CPSF1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CPSF1_HUMAN
  • Myopia 27 (MYP27) [MIM:618827]: A form of myopia, a refractive error of the eye, in which parallel rays from a distant object come to focus in front of the retina, vision being better for near objects than for far. MYP27 patients are affected by early-onset high myopia with increased axial lengths. Fundus changes include optic nerve head crescent and tigroid appearance of the posterior retina. {ECO:0000269 PubMed:30689892}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for CPSF1

genes like me logo Genes that share disorders with CPSF1: view

No data available for Genatlas for CPSF1 Gene

Publications for CPSF1 Gene

  1. CPSF1 mutations are associated with early-onset high myopia and involved in retinal ganglion cell axon projection. (PMID: 30689892) Ouyang J … Zhang Q (Human molecular genetics 2019) 3 4 72
  2. Human Fip1 is a subunit of CPSF that binds to U-rich RNA elements and stimulates poly(A) polymerase. (PMID: 14749727) Kaufmann I … Keller W (The EMBO journal 2004) 3 4 22
  3. The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3'-end formation. (PMID: 7590244) Murthy KG … Manley JL (Genes & development 1995) 2 3 4
  4. The poly A polymerase Star-PAP controls 3'-end cleavage by promoting CPSF interaction and specificity toward the pre-mRNA. (PMID: 21102410) Laishram RS … Anderson RA (The EMBO journal 2010) 3 4
  5. Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation. (PMID: 19224921) Kiefer H … Mikoshiba K (The Journal of biological chemistry 2009) 3 22

Products for CPSF1 Gene

Sources for CPSF1 Gene