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CPPED1 (Calcineurin Like Phosphoesterase Domain Containing 1) is a Protein Coding gene. Diseases associated with CPPED1 include Trichostrongylosis and Trichostrongyloidiasis. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include hydrolase activity and phosphoprotein phosphatase activity.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004721 | phosphoprotein phosphatase activity | IEA | -- |
GO:0016787 | hydrolase activity | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | TAS | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005829 | cytosol | IDA | -- |
GO:0005886 | plasma membrane | IDA | -- |
GO:0035578 | azurophil granule lumen | TAS | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Innate Immune System |
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GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006470 | protein dephosphorylation | IEA | -- |
GO:0043312 | neutrophil degranulation | TAS | -- |
ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | |||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||||
SP3: | - | - | - | - | - | ||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||
SP5: | |||||||||||||||||||||||||||||
SP6: |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CPPED1 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CPPED1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CPPED1 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Cpped1 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Cpped1 30 17 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | CPPED1 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | CPPED1 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | CPPED1 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CPPED1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cpped1 30 |
|
||
Str.265 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | Xl.11444 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | cpped1 30 31 |
|
OneToOne | |
Dr.16752 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.3773 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany | |
-- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 16 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11645068 | - | p.His290Pro | |||
rs1713480 | - | p.Lys241Arg | |||
rs3748976 | - | p.Ala19Asp | |||
rs3748980 | - | p.Val86Ile |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv115e55 | CNV | loss | 17911159 |
dgv2736n100 | CNV | loss | 25217958 |
dgv479e214 | CNV | loss | 21293372 |
dgv4911n54 | CNV | loss | 21841781 |
esv2751549 | CNV | loss | 17911159 |
esv3582011 | CNV | loss | 25503493 |
esv3637967 | CNV | loss | 21293372 |
esv3637968 | CNV | loss | 21293372 |
esv3637969 | CNV | loss | 21293372 |
esv3637972 | CNV | loss | 21293372 |
nsv1043773 | CNV | loss | 25217958 |
nsv1052802 | CNV | loss | 25217958 |
nsv1053617 | CNV | loss | 25217958 |
nsv1070328 | CNV | deletion | 25765185 |
nsv1108988 | CNV | deletion | 24896259 |
nsv473518 | CNV | novel sequence insertion | 20440878 |
nsv525286 | CNV | loss | 19592680 |
nsv571463 | CNV | loss | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
trichostrongylosis |
|
|
trichostrongyloidiasis |
|
|