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This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gen... See more...
Aliases for COX20 Gene
Aliases for COX20 Gene
External Ids for COX20 Gene
- HGNC: 26970
- Entrez Gene: 116228
- Ensembl: ENSG00000203667
- OMIM: 614698
- UniProtKB: Q5RI15
Previous HGNC Symbols for COX20 Gene
- FAM36A
Previous GeneCards Identifiers for COX20 Gene
- GC01P245000
Summaries for COX20 Gene
-
This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
GeneCards Summary for COX20 Gene
COX20 (Cytochrome C Oxidase Assembly Factor COX20) is a Protein Coding gene. Diseases associated with COX20 include Mitochondrial Complex Iv Deficiency and Hypotonia. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Gene Expression.
UniProtKB/Swiss-Prot Summary for COX20 Gene
-
Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:23125284). Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme (PubMed:24403053).
Additional gene information for COX20 Gene
- HGNC(26970)
- Entrez Gene(116228)
- Ensembl(ENSG00000203667)
- OMIM(614698)
- UniProtKB(Q5RI15)
- Open Targets Platform(ENSG00000203667)
- Monarch Initiative
- Search for COX20 at DataMed
- Search for COX20 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for COX20 Gene
Genomics for COX20 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for COX20 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around COX20 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for COX20
Genomic Locations for COX20 Gene
Genomic Locations for COX20 Gene
- chr1:244,835,306-244,845,063
- (GRCh38/hg38)
- Size:
- 9,758 bases
- Orientation:
- Plus strand
- chr1:244,998,624-245,008,359
- (GRCh37/hg19)
- Size:
- 9,736 bases
- Orientation:
- Plus strand
Genomic View for COX20 Gene
Genes around COX20 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q44 by HGNC
- 1q44 by Entrez Gene
- 1q44 by Ensembl
COX20 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for COX20 Gene
Proteins for COX20 Gene
-
Protein details for COX20 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5RI15-COX20_HUMAN
- Recommended name:
- Cytochrome c oxidase assembly protein COX20, mitochondrial
- Protein Accession:
- Q5RI15
- Q8WV86
Protein attributes for COX20 Gene
- Size:
- 118 amino acids
- Molecular mass:
- 13291 Da
- Quaternary structure:
-
- Found in a complex with TMEM177, COA6, MT-CO2/COX2, COX18, SCO1 and SCO2. Interacts with SCO1, SCO2 and COA6 in a MT-CO2/COX2- and COX18-dependent manner (PubMed:29154948, PubMed:24403053, PubMed:28330871). Interacts with COX18 in a MT-CO2/COX2-dependent manner (PubMed:28330871). Interacts with MT-CO2/COX2 (PubMed:29154948, PubMed:24403053, PubMed:23125284, PubMed:28330871). Interacts with TMEM177 (PubMed:29154948).
Protein Expression for COX20 Gene
Post-translational modifications for COX20 Gene
Other Protein References for COX20 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for COX20
- Novus Biologicals Antibodies for COX20
- Invitrogen Antibodies for COX20 (AFLGC-COX20)
- antibodies-online: Show 25 available FAM36A Antibodies ranked by validation data
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for COX20
- Origene Custom Protein Services for COX20
No data available for DME Specific Peptides for COX20 Gene
Domains & Families for COX20 Gene
Gene Families for COX20 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for COX20 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ43269 fis, clone KIDNE2000665, highly similar to Protein FAM36A (B3KM21_HUMAN)
- cDNA FLJ50874 (B4DUR4_HUMAN)
- Protein FAM36A (FA36A_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5RI15- Family:
-
- Belongs to the COX20 family.
Function for COX20 Gene
Molecular function for COX20 Gene
- UniProtKB/Swiss-Prot Function:
- Essential for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase (PubMed:23125284). Acts as a chaperone in the early steps of cytochrome c oxidase subunit II (MT-CO2/COX2) maturation, stabilizing the newly synthesized protein and presenting it to metallochaperones SCO1/2 which in turn facilitates the incorporation of the mature MT-CO2/COX2 into the assembling CIV holoenzyme (PubMed:24403053).
Phenotypes From GWAS Catalog for COX20 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 23125284 |
Phenotypes for COX20 Gene
- MGI mutant phenotypes for COX20:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for COX20:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COX20 - Select products 50% OFF >
- * COX20 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for COX20
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COX20
-
Santa Cruz Biotechnology (SCBT) CRISPR for COX20
miRNA for COX20 Gene
- miRTarBase miRNAs that target COX20
-
- hsa-miR-375 (MIRT019839)
- hsa-miR-25-3p (MIRT186621)
- hsa-miR-32-5p (MIRT186622)
- hsa-miR-33a-3p (MIRT186623)
- hsa-miR-92a-3p (MIRT186624)
- hsa-miR-203a-3p (MIRT186625)
- hsa-miR-299-3p (MIRT186626)
- hsa-miR-363-3p (MIRT186627)
- hsa-miR-367-3p (MIRT186628)
- hsa-miR-380-5p (MIRT186629)
- hsa-miR-92b-3p (MIRT186631)
- hsa-miR-563 (MIRT186632)
- hsa-miR-4307 (MIRT186633)
- hsa-miR-4491 (MIRT186634)
- hsa-miR-4657 (MIRT186635)
- hsa-miR-1273g-5p (MIRT186636)
- hsa-miR-5589-3p (MIRT186637)
- hsa-miR-21-5p (MIRT273114)
- hsa-miR-27b-5p (MIRT273115)
- hsa-miR-590-5p (MIRT273116)
- hsa-miR-7641 (MIRT515222)
- hsa-miR-137 (MIRT515223)
- hsa-miR-203a-5p (MIRT515224)
- hsa-miR-2276-5p (MIRT538406)
- hsa-miR-106a-3p (MIRT538407)
- hsa-miR-4634 (MIRT538408)
- hsa-miR-645 (MIRT538409)
- hsa-miR-652-3p (MIRT538410)
- hsa-miR-454-3p (MIRT538411)
- hsa-miR-4295 (MIRT538412)
- hsa-miR-3666 (MIRT538413)
- hsa-miR-301b-3p (MIRT538414)
- hsa-miR-301a-3p (MIRT538415)
- hsa-miR-130b-3p (MIRT538416)
- hsa-miR-130a-3p (MIRT538417)
- hsa-miR-5586-3p (MIRT538418)
- hsa-miR-8057 (MIRT643865)
- hsa-miR-24-3p (MIRT643866)
- hsa-miR-4284 (MIRT643867)
- hsa-miR-4772-3p (MIRT643868)
- hsa-miR-3615 (MIRT643869)
- hsa-miR-1304-3p (MIRT643870)
- hsa-miR-125b-1-3p (MIRT643871)
- hsa-miR-6890-3p (MIRT643872)
- hsa-miR-6800-3p (MIRT643873)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COX20
- Browse OriGene Inhibitory RNA Products For COX20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COX20
Clone Products
- Applied Biological Materials (abm): Clones for COX20 - Select products 50% OFF >
- * COX20 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for COX20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COX20
Cell Line Products
-
Horizon Cell Lines for COX20
No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for COX20 Gene
Localization for COX20 Gene
Subcellular locations from UniProtKB/Swiss-Prot for COX20 Gene
- Mitochondrion inner membrane. Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| mitochondrion | 5 |
| cytosol | 2 |
| extracellular | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| lysosome | 0 |
- Mitochondria (4)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005739 | mitochondrion | IBA,IDA | -- |
| GO:0005743 | mitochondrial inner membrane | IDA | 23125284 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for COX20 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
.40
|
|
| 2 | Gene Expression |
.48
|
|
| 3 | Metabolism |
.40
|
|
| 4 | TP53 Regulates Metabolic Genes | ||
| 5 | Regulation of TP53 Activity | ||
Pathways by source for COX20 Gene
1 KEGG pathway for COX20 Gene
Interacting Proteins for COX20 Gene
Selected Interacting proteins:
Q5RI15-COX20_HUMAN
ENSP00000406327
for COX20 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for COX20
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0033617 | mitochondrial respiratory chain complex IV assembly | IBA,IMP | 23125284 |
No data available for SIGNOR curated interactions for COX20 Gene
Transcripts for COX20 Gene
mRNA/cDNA for COX20 Gene
- 5 REFSEQ mRNAs :
- 18 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000411948 2295 nts (view in UCSC)
- ENST00000366528 568 nts (view in UCSC)
- ENST00000391839 1005 nts (view in UCSC)
- ENST00000498262 2290 nts (view in UCSC)
- ENST00000464757 2616 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COX20 - Select products 50% OFF >
- * COX20 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for COX20
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COX20
-
Santa Cruz Biotechnology (SCBT) CRISPR for COX20
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COX20
- Browse OriGene Inhibitory RNA Products For COX20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COX20
Clone Products
- Applied Biological Materials (abm): Clones for COX20 - Select products 50% OFF >
- * COX20 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for COX20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COX20
Relevant External Links for COX20 Gene
- GeneLoc Exon Structure for
- COX20
Expression for COX20 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Inner Cell Mass (Early Embryonic Tissues)
This gene is overexpressed in Bone (8.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for COX20 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for COX20
SOURCE GeneReport for Unigene cluster for COX20 Gene:
Hs.411490Evidence on tissue expression from TISSUES for COX20 Gene
- Nervous system(4.5)
- Muscle(2.4)
- Kidney(2.3)
- Heart(2.2)
Phenotype-based relationships between genes and organs from Gene ORGANizer for COX20 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- immune
- integumentary
- nervous
- respiratory
- skeletal muscle
- urinary
Regions:
Head and neck:
- brain
- cerebrospinal fluid
- cranial nerve
- ear
- eye
- eyelid
- face
- head
- meninges
- neck
Thorax:
- bronchus
- heart
- heart valve
- lung
- trachea
Abdomen:
- kidney
- liver
General:
- blood
- blood vessel
- coagulation system
- peripheral nervous system
- red blood cell
- skin
Primer Products
-
OriGene qPCR primer pairs for COX20
-
OriGene qPCR primer pairs and template standards for COX20
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for COX20 Gene
Orthologs for COX20 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | COX20 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | COX20 30 |
|
||
| FAM36A 31 |
|
OneToOne | |||
| Dog (Canis familiaris) |
Mammalia | COX20 30 |
|
||
| Rat (Rattus norvegicus) |
Mammalia | Cox20 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cox20 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | COX20 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | COX20 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | COX20 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | COX20 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100497666 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | zgc:92598 30 |
|
||
| COX20 31 |
|
OneToOne | |||
| Fruit Fly (Drosophila melanogaster) |
Insecta | l(3)87Df 31 |
|
OneToOne |
- Species where no ortholog for COX20 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for COX20 Gene
- ENSEMBL:
- Gene Tree for COX20 (if available)
- TreeFam:
- Gene Tree for COX20 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for COX20: view image
Paralogs for COX20 Gene
(1) SIMAP similar genes for COX20 Gene using alignment to 1 proteins:
- COX20_HUMAN
Pseudogenes.org Pseudogenes for COX20 Gene
No data available for Paralogs for COX20 Gene
Variants for COX20 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for COX20 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 673679 | Likely Benign: not provided | 244,842,507(+) | C/T | INTRON_VARIANT | |
| 683598 | Benign: not provided | 244,841,783(+) | G/C | INTRON_VARIANT | |
| 683599 | Benign: not provided | 244,842,411(+) | A/C | INTRON_VARIANT | |
| 683601 | Benign: not provided | 244,842,526(+) | C/T | INTRON_VARIANT | |
| 683603 | Benign: not provided | 244,842,539(+) | T/A | INTRON_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2669232 | CNV | deletion | 23128226 |
| esv2726684 | CNV | deletion | 23290073 |
| nsv549493 | CNV | gain | 21841781 |
Residual Variation Intolerance Score:
63% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.76;
16.04% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for COX20 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COX20 Gene
Disorders for COX20 Gene
(9) MalaCards diseases for COX20 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| mitochondrial complex iv deficiency |
|
|
| hypotonia |
|
|
| transient neonatal thrombocytopenia |
|
|
| transient neonatal neutropenia |
|
|
| leigh syndrome |
|
|
Search COX20 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
COX20_HUMAN- Mitochondrial complex IV deficiency (MT-C4D) [MIM:220110]: A disorder of the mitochondrial respiratory chain with heterogeneous clinical manifestations, ranging from isolated myopathy to severe multisystem disease affecting several tissues and organs. Features include hypertrophic cardiomyopathy, hepatomegaly and liver dysfunction, hypotonia, muscle weakness, exercise intolerance, developmental delay, delayed motor development and mental retardation. Some affected individuals manifest a fatal hypertrophic cardiomyopathy resulting in neonatal death. A subset of patients manifest Leigh syndrome. {ECO:0000269 PubMed:23125284, ECO:0000269 PubMed:24202787, ECO:0000269 PubMed:29154948}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for COX20
No data available for Genatlas for COX20 Gene
Publications for COX20 Gene
- A mutation in the FAM36A gene, the human ortholog of COX20, impairs cytochrome c oxidase assembly and is associated with ataxia and muscle hypotonia. (PMID: 23125284) Szklarczyk R … van den Heuvel LP (Human molecular genetics 2013) 2 3 4
- Iterative orthology prediction uncovers new mitochondrial proteins and identifies C12orf62 as the human ortholog of COX14, a protein involved in the assembly of cytochrome c oxidase. (PMID: 22356826) Szklarczyk R … Huynen MA (Genome biology 2012) 2 3 4
- The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis. (PMID: 29154948) Lorenzi I … Rehling P (Biochimica et biophysica acta. Molecular cell research 2018) 3 4
- Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module. (PMID: 28330871) Bourens M … Barrientos A (The Journal of biological chemistry 2017) 3 4
- Recessive dystonia-ataxia syndrome in a Turkish family caused by a COX20 (FAM36A) mutation. (PMID: 24202787) Doss S … Klein C (Journal of neurology 2014) 3 4
ExternalLinks
Products for COX20 Gene
- Custom Antibody ServicesOriGene Antibodies for COX20
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for COX20
- Origene Custom Protein Services for COX20
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COX20
- Browse OriGene Inhibitory RNA Products For COX20
- OriGene qPCR primer pairs for COX20
- OriGene qPCR primer pairs and template standards for COX20
- OriGene CRISPR knockouts for COX20
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For COX20
- Sino Biological Human cDNA Clone for COX20
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for COX20
- Novus Biologicals proteins and lysates for COX20
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for COX20 (AFLGC-COX20)
- VectorBuilder Custom and pre-made DNA vectors for COX20 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for COX20 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for COX20 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for COX20 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for COX20
- antibodies-online: Show 25 available FAM36A Antibodies ranked by validation data
- antibodies-online: Search results for available FAM36A related products ranked by validation data
- antibodies-online: Search results for available FAM36A related products ranked by validation data
- Horizon Cell Lines for COX20
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COX20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COX20
- Search GeneCopoeia for miRNA 3'UTR Target clone products for COX20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COX20
Sources for COX20 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
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