Aliases for COMMD6 Gene
External Ids for COMMD6 Gene
Previous GeneCards Identifiers for COMMD6 Gene
COMMD6 belongs to a family of NF-kappa-B (see RELA; MIM 164014)-inhibiting proteins characterized by the presence of a COMM domain (see COMMD1; MIM 607238) (de Bie et al., 2006 [PubMed 16573520]).[supplied by OMIM, Mar 2009]
GeneCards Summary for COMMD6 Gene
COMMD6 (COMM Domain Containing 6) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include NF-kappaB binding.
UniProtKB/Swiss-Prot for COMMD6 Gene
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation.