Aliases for COLEC10 Gene
External Ids for COLEC10 Gene
Previous GeneCards Identifiers for COLEC10 Gene
This gene encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. [provided by RefSeq, Jul 2008]
GeneCards Summary for COLEC10 Gene
COLEC10 (Collectin Subfamily Member 10) is a Protein Coding gene. Diseases associated with COLEC10 include 3Mc Syndrome 3 and 3Mc Syndrome. Among its related pathways are Innate Immune System and Creation of C4 and C2 activators. Gene Ontology (GO) annotations related to this gene include mannose binding. An important paralog of this gene is COLEC11.
UniProtKB/Swiss-Prot Summary for COLEC10 Gene
Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine (PubMed:10224141). Acts as a chemoattractant, probably involved in the regulation of cell migration (PubMed:28301481).