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This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, result... See more...
Aliases for COL3A1 Gene
Aliases for COL3A1 Gene
External Ids for COL3A1 Gene
- HGNC: 2201
- Entrez Gene: 1281
- Ensembl: ENSG00000168542
- OMIM: 120180
- UniProtKB: P02461
Previous HGNC Symbols for COL3A1 Gene
- EDS4A
Previous GeneCards Identifiers for COL3A1 Gene
- GC02P187975
- GC02P188522
- GC02P189803
- GC02P190041
- GC02P189664
- GC02P189547
- GC02P181698
Summaries for COL3A1 Gene
-
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]
GeneCards Summary for COL3A1 Gene
COL3A1 (Collagen Type III Alpha 1 Chain) is a Protein Coding gene. Diseases associated with COL3A1 include Ehlers-Danlos Syndrome, Vascular Type and Polymicrogyria With Or Without Vascular-Type Ehlers-Danlos Syndrome. Among its related pathways are Integrin Pathway and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding and SMAD binding. An important paralog of this gene is COL1A1.
UniProtKB/Swiss-Prot Summary for COL3A1 Gene
-
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
Additional gene information for COL3A1 Gene
- HGNC(2201)
- Entrez Gene(1281)
- Ensembl(ENSG00000168542)
- OMIM(120180)
- UniProtKB(P02461)
- Open Targets Platform(ENSG00000168542)
- Monarch Initiative
- Search for COL3A1 at DataMed
- Search for COL3A1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for COL3A1 Gene
Genomics for COL3A1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for COL3A1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around COL3A1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for COL3A1
- Top Transcription factor binding sites by QIAGEN in the COL3A1 gene promoter:
-
- Bach2
- FOXD1
- Hlf
- NF-kappaB
- NF-kappaB1
- Nkx2-5
- Pbx1a
- POU3F2
- POU3F2 (N-Oct-5a)
- POU3F2 (N-Oct-5b)
Genomic Locations for COL3A1 Gene
Genomic Locations for COL3A1 Gene
- chr2:188,974,373-189,012,746
- (GRCh38/hg38)
- Size:
- 38,374 bases
- Orientation:
- Plus strand
- chr2:189,839,046-189,877,472
- (GRCh37/hg19)
- Size:
- 38,427 bases
- Orientation:
- Plus strand
Genomic View for COL3A1 Gene
Genes around COL3A1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q32.2 by HGNC
- 2q32.2 by Entrez Gene
- 2q32.2 by Ensembl
COL3A1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for COL3A1 Gene
Proteins for COL3A1 Gene
-
Protein details for COL3A1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02461-CO3A1_HUMAN
- Recommended name:
- Collagen alpha-1(III) chain
- Protein Accession:
- P02461
- D2JYH5
- D3DPH4
- P78429
- Q15112
- Q16403
- Q53S91
- Q541P8
- Q6LDB3
- Q6LDJ2
- Q6LDJ3
- Q7KZ56
- Q8N6U4
- Q9UC88
- Q9UC89
- Q9UC90
- Q9UC91
- R4N3C5
- V9GZI1
Protein attributes for COL3A1 Gene
- Size:
- 1466 amino acids
- Molecular mass:
- 138564 Da
- Quaternary structure:
-
- Trimers of identical alpha 1(III) chains. The chains are linked to each other by interchain disulfide bonds. Trimers are also cross-linked via hydroxylysines. Interacts with ADGRG1 (PubMed:28258187).
Three dimensional structures from OCA and Proteopedia for COL3A1 Gene
Protein Expression for COL3A1 Gene
Post-translational modifications for COL3A1 Gene
- Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.
- O-linked glycan consists of a Glc-Gal disaccharide bound to the oxygen atom of a post-translationally added hydroxyl group.
-
Glycosylation at Lys263, Asn1367, and Ser1145
- NX_P02461 (NX_P02461-1)
- Modification sites at PhosphoSitePlus
-
Glycosylation from GlyConnect
- CO3A1_HUMAN (1127)
Other Protein References for COL3A1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- SouthernBiotech Goat Anti-Type III Collagen-BIOT and Goat Anti-Type III Collagen-UNLB
- NSJ Bioreagents Collagen III Antibody / COL3A1
- HUABIO Anti-Collagen III Antibody
- Novus Biologicals Antibodies for COL3A1
-
Abcam antibodies for COL3A1
- Invitrogen Antibodies for COL3A1 (AFLGC-COL3A1)
- antibodies-online: Show 199 available COL3A1 Antibodies ranked by validation data
- Compare Top COL3A1 Antibodies
-
Recommended
- 109 WB Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 IHC (fro) Antibody (anti-human)
- 43 WB Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 51 WB Antibodies (anti-rat)
- 4 IHC Antibodies (anti-rat)
- 3 IF Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for COL3A1
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for COL3A1
- Origene Custom Protein Services for COL3A1
- Novus Biologicals proteins for COL3A1
- ProSpec Recombinant Proteins for COL3A1
-
ProSci Proteins for COL3A1
-
Abcam proteins for COL3A1
Assay Products
- Novus Biologicals ELISA Kits for COL3A1
- antibodies-online: Show 57 available COL3A1 Elisa Kits ranked by validation data
- Compare Top COL3A1 Elisa Kits
-
Quality Products:
- ABIN1114255
- ABIN577483
- ABIN415201
- ABIN5520224
- ABIN5668419
- ABIN1569092
- ABIN5591844
- ABIN509881
- ABIN454774
- ABIN5653121
- ABIN831837
- ABIN426367
- ABIN5591845
- ABIN627614
- ABIN5674676
- ABIN5653122
- ABIN6202944
- ABIN2946506
- ABIN6202945
- ABIN454775
- ABIN831838
- ABIN433479
- ABIN1884400
- ABIN1569093
- ABIN626792
- ABIN5591846
- ABIN5653123
- ABIN6254326
- ABIN2543164
- ABIN4968193
- ABIN1560702
- ABIN1052261
- ABIN6202941
- ABIN1127404
No data available for DME Specific Peptides for COL3A1 Gene
Domains & Families for COL3A1 Gene
Gene Families for COL3A1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for COL3A1 Gene
- InterPro:
- Blocks:
-
- Collagen triple helix repeat
- Collagen helix repeat
- von Willebrand factor, type C
- Fibrillar collagen, C-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for COL3A1 Gene
- GenScript: Design optimal peptide antigens:
-
- Collagen alpha-1(III) chain (CO3A1_HUMAN)
- Collagen, type III, alpha 1 (D2JYH5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P02461UniProtKB/Swiss-Prot:
CO3A1_HUMAN :- The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function.
- Belongs to the fibrillar collagen family.
- Domain:
-
- The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function.
- Family:
-
- Belongs to the fibrillar collagen family.
Function for COL3A1 Gene
Molecular function for COL3A1 Gene
- UniProtKB/Swiss-Prot Function:
- Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12.
- GENATLAS Biochemistry:
- collagen type III,alpha 1,fibril forming,putative down-regulated c-Myc target gene,
Phenotypes From GWAS Catalog for COL3A1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002020 | protease binding | IPI | 19932771 |
| GO:0005178 | integrin binding | NAS | 14970208 |
| GO:0005201 | extracellular matrix structural constituent | IMP | 7487954 |
| GO:0005515 | protein binding | IPI | 2839553 |
| GO:0030020 | extracellular matrix structural constituent conferring tensile strength | RCA | 25037231 |
Phenotypes for COL3A1 Gene
- MGI mutant phenotypes for COL3A1:
-
inferred from 4 alleles
- immune system phenotype
- respiratory system phenotype
- cardiovascular system phenotype
- cellular phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- liver/biliary system phenotype
- digestive/alimentary phenotype
- hematopoietic system phenotype
- integument phenotype
- adipose tissue phenotype
- GenomeRNAi human phenotypes for COL3A1:
Animal Models for COL3A1 Gene
- MGI Knock Outs for COL3A1:
-
- Col3a1 Col3a1<tm1Jae>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COL3A1 - Select products 50% OFF >
- * COL3A1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for COL3A1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL3A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL3A1
miRNA for COL3A1 Gene
- miRTarBase miRNAs that target COL3A1
-
- hsa-miR-29c-3p (MIRT000927)
- mmu-miR-29a-3p (MIRT003673)
- mmu-miR-29b-3p (MIRT003682)
- hsa-miR-29b-3p (MIRT005567)
- rno-miR-29b-3p (MIRT007452)
- hsa-miR-335-5p (MIRT018299)
- hsa-miR-29a-3p (MIRT028683)
- hsa-miR-455-3p (MIRT037808)
- hsa-let-7b-5p (MIRT054120)
- hsa-miR-767-5p (MIRT437563)
- hsa-miR-143-3p (MIRT438362)
- mmu-let-7e-5p (MIRT732895)
- hsa-miR-29b-1-5p (MIRT734149)
- hsa-let-7d-5p (MIRT734638)
- hsa-miR-29a-5p (MIRT734764)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COL3A1
- Browse OriGene Inhibitory RNA Products For COL3A1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COL3A1
Clone Products
- Applied Biological Materials (abm): Clones for COL3A1 - Select products 50% OFF >
- * COL3A1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for COL3A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL3A1
Cell Line Products
-
Horizon Cell Lines for COL3A1
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for COL3A1 Gene
Localization for COL3A1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for COL3A1 Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 4 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| cytosol | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Endoplasmic reticulum (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | HDA,TAS | -- |
| GO:0005581 | collagen trimer | IEA | -- |
| GO:0005586 | collagen type III trimer | IBA,NAS | 1672129 |
| GO:0005615 | extracellular space | IBA,NAS | 9036918 |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
Pathways & Interactions for COL3A1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Collagen chain trimerization |
Intrinsic Prothrombin Activation Pathway
.48
Blood Coagulation Cascade
.46
|
|
| 2 | Integrin Pathway |
FAK1 Signaling
.67
Integrin Pathway
.67
GnRH Signaling
.56
|
UPA-UPAR Pathway
.56
Inhibition of Angiogenesis by TSP1
.50
Transendothelial Migration of Leukocytes
.38
|
| 3 | ERK Signaling |
ERK Signaling
.61
Rho Family GTPases
.61
MAPK Signaling
.58
|
Molecular Mechanisms of Cancer
.51
ILK Signaling
.49
|
| 4 | Phospholipase-C Pathway |
Phospholipase-C Pathway
.56
|
PTEN Pathway
.56
|
| 5 | Binding and Uptake of Ligands by Scavenger Receptors | ||
Pathways by source for COL3A1 Gene
5 BioSystems pathways for COL3A1 Gene
8 Reactome pathways for COL3A1 Gene
1 PharmGKB pathway for COL3A1 Gene
5 KEGG pathways for COL3A1 Gene
1 GeneGo (Thomson Reuters) pathway for COL3A1 Gene
- Cell adhesion_ECM remodeling
15 Qiagen pathways for COL3A1 Gene
- Blood Coagulation Cascade
- ERK Signaling
- FAK1 Signaling
- GnRH Signaling
- ILK Signaling
Interacting Proteins for COL3A1 Gene
Selected Interacting proteins:
P02461-CO3A1_HUMAN
ENSP00000304408
for COL3A1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for COL3A1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001501 | skeletal system development | IEA | -- |
| GO:0001568 | blood vessel development | IEA | -- |
| GO:0007160 | cell-matrix adhesion | IDA | 16912226 |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | IDA | 16360482 |
| GO:0007229 | integrin-mediated signaling pathway | IMP | 14970208 |
Drugs & Compounds for COL3A1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Collagenase | Approved, Investigational | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- SouthernBiotech Human Type III Collagen-Solution
Transcripts for COL3A1 Gene
mRNA/cDNA for COL3A1 Gene
- 2 REFSEQ mRNAs :
- 15 NCBI additional mRNA sequence :
- 6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000304636 5490 nts (view in UCSC)
- ENST00000470167 628 nts (view in UCSC)
- ENST00000450867 268 nts (view in UCSC)
- ENST00000467886 226 nts (view in UCSC)
- ENST00000487010 2054 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COL3A1 - Select products 50% OFF >
- * COL3A1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for COL3A1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL3A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL3A1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COL3A1
- Browse OriGene Inhibitory RNA Products For COL3A1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COL3A1
Clone Products
- Applied Biological Materials (abm): Clones for COL3A1 - Select products 50% OFF >
- * COL3A1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for COL3A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL3A1
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | · | 2c | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30 | ^ | 31a | · | 31b | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37a | · | 37b | ^ | 38a | · | 38b | ^ | 39 | ^ | 40 | ^ | 41 | ^ | 42 | ^ | 43 | ^ | 44 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||
| SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 45 | ^ | 46 | ^ | 47 | ^ | 48a | · | 48b | · | 48c | ^ | 49 | ^ | 50a | · | 50b | ^ | 51a | · | 51b | ^ | 52a | · | 52b | · | 52c | · | 52d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | ||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | |||||||||||||||||||||||
| SP7: | |||||||||||||||||||||||||||||
| SP8: |
Relevant External Links for COL3A1 Gene
- GeneLoc Exon Structure for
- COL3A1
Expression for COL3A1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Limb (Muscoskeletal System)
- Central Intermediate Lamina Cells Autopod Synovial Joint
- Interzone Cells Autopod Synovial Joint
- Central Intermediate Lamina Cells Zeugopod Synovial Joint
- Interzone Cells Stylopod Synovial Joint
- Interzone Cells Zeugopod Synovial Joint
-
Cartilage (Muscoskeletal System)
- Central Intermediate Lamina Cells Autopod Synovial Joint
- Interzone Cells Autopod Synovial Joint
- Central Intermediate Lamina Cells Zeugopod Synovial Joint
- Interzone Cells Stylopod Synovial Joint
- Interzone Cells Zeugopod Synovial Joint
-
Bone (Muscoskeletal System)
- Presumptive Suture Cells Rostral Sutures
- Suture Cells Facial Sutures
- Suture Cells Rostral Sutures
- Presumptive Suture Cells Facial Sutures
-
Dermis (Integumentary System)
- Dermal Fibroblasts Ventral Dermis
- Dermal Fibroblasts Cranial Dermis
- Dermal Fibroblasts Dorsal Dermis
-
Fibroblasts
- Dermal Fibroblasts Ventral Dermis
- Dermal Fibroblasts Cranial Dermis
- Dermal Fibroblasts Dorsal Dermis
This gene is overexpressed in Lung (12.7), Gallbladder (11.0), and Urinary Bladder (6.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for COL3A1 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for COL3A1
SOURCE GeneReport for Unigene cluster for COL3A1 Gene:
Hs.443625Evidence on tissue expression from TISSUES for COL3A1 Gene
- Skin(4.8)
- Pancreas(4.7)
- Liver(4.6)
- Bone(4.6)
- Eye(4.6)
- Lung(4.5)
- Heart(4.5)
- Intestine(4.4)
- Nervous system(4.3)
- Stomach(4.1)
- Muscle(3.6)
- Kidney(3.6)
- Gall bladder(3.2)
- Spleen(2.9)
- Lymph node(2.8)
- Thyroid gland(2.8)
- Blood(2.7)
Phenotype-based relationships between genes and organs from Gene ORGANizer for COL3A1 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- cardiovascular
- digestive
- endocrine
- immune
- integumentary
- nervous
- reproductive
- respiratory
- skeletal muscle
- skeleton
- urinary
Regions:
Head and neck:
- brain
- chin
- ear
- eye
- eyelid
- face
- forehead
- head
- jaw
- larynx
- lip
- mandible
- maxilla
- mouth
- neck
- nose
- outer ear
- pharynx
- scalp
- skull
- tooth
Thorax:
- aorta
- bronchus
- chest wall
- clavicle
- diaphragm
- esophagus
- heart
- heart valve
- lung
- rib
- rib cage
- scapula
- sternum
- trachea
Abdomen:
- abdominal wall
- intestine
- kidney
- large intestine
- liver
- pancreas
- small intestine
- stomach
Pelvis:
- pelvis
- rectum
- testicle
- ureter
- urethra
- urinary bladder
- uterus
Limb:
- ankle
- arm
- digit
- elbow
- femur
- fibula
- finger
- foot
- forearm
- hand
- hip
- humerus
- knee
- lower limb
- radius
- shin
- shoulder
- thigh
- tibia
- toe
- ulna
- upper limb
- wrist
General:
- blood
- blood vessel
- coagulation system
- hair
- peripheral nerve
- peripheral nervous system
- skin
- spinal column
- vertebrae
Primer Products
-
OriGene qPCR primer pairs for COL3A1
-
OriGene qPCR primer pairs and template standards for COL3A1
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for COL3A1 Gene
Orthologs for COL3A1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | COL3A1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | COL3A1 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | COL3A1 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Col3a1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Col3a1 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | COL3A1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | COL3A1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | COL3A1 30 |
|
||
| -- 31 |
|
ManyToMany | |||
| Lizard (Anolis carolinensis) |
Reptilia | COL3A1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | col3a1 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Cg25C 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.7880 31 |
|
OneToMany |
- Species where no ortholog for COL3A1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
- Zebrafish (Danio rerio)
Evolution for COL3A1 Gene
- ENSEMBL:
- Gene Tree for COL3A1 (if available)
- TreeFam:
- Gene Tree for COL3A1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for COL3A1: view image
Paralogs for COL3A1 Gene
Paralogs for COL3A1 Gene
- COL1A1 5
- COL2A1 5
- COL1A2 5
- COL7A1 5
- COL5A1 5
- COL11A1 5
- COL11A2 5
- COL5A3 5
- COL4A1 5
- COL4A5 5
- COL4A2 5
- COL4A6 5
- COL4A4 5
- COL4A3 5
- COL16A1 5
- COL22A1 5
- COL5A2 5
- COL24A1 5
- COL27A1 5
- COL18A1 5
- COL17A1 5
- COL15A1 5
- COL28A1 5
- COL9A1 5
- COL9A3 5
- COL6A1 5
- COL9A2 5
- COL6A2 5
- COL13A1 5
- COL20A1 5
- COL25A1 5
- COL21A1 5
- COL23A1 5
- COLQ 5
- EMID1 5
- COL26A1 5
- EDA 5
(17) SIMAP similar genes for COL3A1 Gene using alignment to 10 proteins:
- CO3A1_HUMAN
- D2JYH5_HUMAN
- E7ENY8_HUMAN
- H7C435_HUMAN
- R4N3C5_HUMAN
- V9GZG2_HUMAN
- V9GZI1_HUMAN
- V9GZL2_HUMAN
- V9GZM1_HUMAN
- V9GZS3_HUMAN
Variants for COL3A1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for COL3A1 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 101134 | Pathogenic: Ehlers-Danlos syndrome, type 4 | 188,994,960(+) | ATGACATAAAAATATT | SPLICE_ACCEPTOR_VARIANT,SPLICE_DONOR_VARIANT | |
| 101300 | Pathogenic: Ehlers-Danlos syndrome, type 4 | 188,996,507(+) | TCATTAATTTCTTCAA | ||
| 101348 | Pathogenic: Ehlers-Danlos syndrome, type 4 | 189,006,076(+) | TAAGATTTCTTACCCC | SPLICE_ACCEPTOR_VARIANT,SPLICE_DONOR_VARIANT | |
| 101394 | Pathogenic: Ehlers-Danlos syndrome, type 4 | 188,988,189(+) | ATATATATTCTGCTAT | SPLICE_ACCEPTOR_VARIANT,SPLICE_DONOR_VARIANT | |
| 101415 | Pathogenic: Ehlers-Danlos syndrome, type 4 | 189,005,609(+) | AGGATAGACTTAAAAG | SPLICE_ACCEPTOR_VARIANT,SPLICE_DONOR_VARIANT |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv7233n54 | CNV | loss | 21841781 |
| dgv7234n54 | CNV | loss | 21841781 |
| esv1030122 | CNV | deletion | 17803354 |
| esv2203663 | CNV | deletion | 18987734 |
| esv2721255 | CNV | deletion | 23290073 |
| esv2721256 | CNV | deletion | 23290073 |
| esv2721257 | CNV | deletion | 23290073 |
| esv3360634 | CNV | insertion | 20981092 |
| esv3371950 | CNV | insertion | 20981092 |
| esv3893522 | CNV | loss | 25118596 |
| esv990670 | CNV | deletion | 20482838 |
| esv993048 | CNV | deletion | 20482838 |
| nsv1114155 | CNV | deletion | 24896259 |
| nsv459992 | CNV | loss | 19166990 |
| nsv834490 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
7.98% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.78;
86.75% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for COL3A1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COL3A1 Gene
Disorders for COL3A1 Gene
(48) MalaCards diseases for COL3A1 Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ehlers-danlos syndrome, vascular type |
|
|
| polymicrogyria with or without vascular-type ehlers-danlos syndrome |
|
|
| acrogeria, gottron type |
|
|
| familial thoracic aortic aneurysm and aortic dissection |
|
|
| visual epilepsy |
|
|
Search COL3A1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
CO3A1_HUMAN- Ehlers-Danlos syndrome, vascular type (EDSVASC) [MIM:130050]: A severe form of Ehlers-Danlos syndrome, a group of connective tissue disorders characterized by skin hyperextensibility, articular hypermobility, and tissue fragility. EDSVASC is an autosomal dominant disease characterized by joint and dermal manifestations as in other forms of the syndrome, and by proneness to spontaneous rupture of bowel and large arteries. The vascular complications may affect all anatomical areas. {ECO:0000269 PubMed:10706896, ECO:0000269 PubMed:10923041, ECO:0000269 PubMed:11168790, ECO:0000269 PubMed:12694234, ECO:0000269 PubMed:12786757, ECO:0000269 PubMed:1352273, ECO:0000269 PubMed:1357232, ECO:0000269 PubMed:1370809, ECO:0000269 PubMed:1496983, ECO:0000269 PubMed:1895316, ECO:0000269 PubMed:2243125, ECO:0000269 PubMed:2349939, ECO:0000269 PubMed:2492273, ECO:0000269 PubMed:2808425, ECO:0000269 PubMed:7749417, ECO:0000269 PubMed:7833919, ECO:0000269 PubMed:7912131, ECO:0000269 PubMed:8019562, ECO:0000269 PubMed:8098182, ECO:0000269 PubMed:8411057, ECO:0000269 PubMed:8514866, ECO:0000269 PubMed:8664902, ECO:0000269 PubMed:8680408, ECO:0000269 PubMed:8884076, ECO:0000269 PubMed:8990011, ECO:0000269 PubMed:9036918, ECO:0000269 PubMed:9147870, ECO:0000269 PubMed:9452103, ECO:0000269 Ref.50, ECO:0000269 Ref.55}. Note=The disease is caused by mutations affecting the gene represented in this entry.
- Polymicrogyria with or without vascular-type Ehlers-Danlos syndrome (PMGEDSV) [MIM:618343]: An autosomal recessive disorder with a highly variable phenotype and onset in early childhood. Disease features include cobblestone-like malformation of the cortex, polymicrogyria, intellectual and motor developmental delay, small joint hypermobility, vascular fragility, aneurysms, thin translucent skin and easy bruising, congenital heart defects, and foot deformities. Early death due to vascular dissection may occur. {ECO:0000269 PubMed:19455184, ECO:0000269 PubMed:25205403, ECO:0000269 PubMed:28258187, ECO:0000269 PubMed:28742248}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for COL3A1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for COL3A1 Gene
Publications for COL3A1 Gene
- Mutation of ACTA2 gene as an important cause of familial and nonfamilial nonsyndromatic thoracic aortic aneurysm and/or dissection (TAAD). (PMID: 19639654) Morisaki H … Morisaki T (Human mutation 2009) 3 23 41
- Collagen type III alpha I is a gastro-oesophageal reflux disease susceptibility gene and a male risk factor for hiatus hernia. (PMID: 19398442) Asling B … Lagerström-Fermer M (Gut 2009) 3 23 41
- The relationship between COL3A1 exon 31 polymorphism and pelvic organ prolapse. (PMID: 19152942) Jeon MJ … Bai SW (The Journal of urology 2009) 3 23 41
- Collagen type 3 alpha 1 polymorphism and risk of pelvic organ prolapse. (PMID: 18722615) Chen HY … Tsai CH (International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2008) 3 23 41
- [Correlation of COL3A1 gene with type III collagen stability in intracranial aneurysm]. (PMID: 18642782) Hua T … Zhao JZ (Zhonghua yi xue za zhi 2008) 3 23 41
ExternalLinks
Products for COL3A1 Gene
- Custom Antibody ServicesOriGene Antibodies for COL3A1
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for COL3A1
- Origene Custom Protein Services for COL3A1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COL3A1
- Browse OriGene Inhibitory RNA Products For COL3A1
- OriGene qPCR primer pairs for COL3A1
- OriGene qPCR primer pairs and template standards for COL3A1
- OriGene CRISPR knockouts for COL3A1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For COL3A1
- Sino Biological Human cDNA Clone for COL3A1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for COL3A1
- Novus Biologicals proteins for COL3A1
- Novus Biologicals ELISA Kits for COL3A1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for COL3A1
- Abcam proteins for COL3A1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for COL3A1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for COL3A1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for COL3A1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for COL3A1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for COL3A1
- antibodies-online: Show 199 available COL3A1 Antibodies ranked by validation data
- Compare Top COL3A1 Antibodies
- Recommended
- 109 WB Antibodies (anti-human)
- 4 IHC Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 IHC (fro) Antibody (anti-human)
- 43 WB Antibodies (anti-mouse)
- 4 IHC Antibodies (anti-mouse)
- 51 WB Antibodies (anti-rat)
- 4 IHC Antibodies (anti-rat)
- 3 IF Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- antibodies-online: Show 57 available COL3A1 Elisa Kits ranked by validation data
- Compare Top COL3A1 Elisa Kits
- Quality Products:
- ABIN1114255
- ABIN577483
- ABIN415201
- ABIN5520224
- ABIN5668419
- ABIN1569092
- ABIN5591844
- ABIN509881
- ABIN454774
- ABIN5653121
- ABIN831837
- ABIN426367
- ABIN5591845
- ABIN627614
- ABIN5674676
- ABIN5653122
- ABIN6202944
- ABIN2946506
- ABIN6202945
- ABIN454775
- ABIN831838
- ABIN433479
- ABIN1884400
- ABIN1569093
- ABIN626792
- ABIN5591846
- ABIN5653123
- ABIN6254326
- ABIN2543164
- ABIN4968193
- ABIN1560702
- ABIN1052261
- ABIN6202941
- ABIN1127404
- antibodies-online: Show 15 available COL3A1 Proteins ranked by validation data
- Compare Top COL3A1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for COL3A1
- Search Santa Cruz Biotechnology (SCBT) for COL3A1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for COL3A1
- Search for COL3A1 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for COL3A1
- Horizon Cell Lines for COL3A1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL3A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL3A1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for COL3A1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COL3A1
Sources for COL3A1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB