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This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016] See more...
Aliases for COL21A1 Gene
Aliases for COL21A1 Gene
External Ids for COL21A1 Gene
- HGNC: 17025
- Entrez Gene: 81578
- Ensembl: ENSG00000124749
- OMIM: 610002
- UniProtKB: Q96P44
Previous GeneCards Identifiers for COL21A1 Gene
- GC06M055923
- GC06M055968
- GC06M056029
- GC06M055756
Summaries for COL21A1 Gene
-
This gene encodes the alpha chain of type XXI collagen, a member of the FACIT (fibril-associated collagens with interrupted helices) collagen family. Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for COL21A1 Gene
COL21A1 (Collagen Type XXI Alpha 1 Chain) is a Protein Coding gene. Among its related pathways are Integrin Pathway and Collagen chain trimerization. An important paralog of this gene is COL18A1.
Additional gene information for COL21A1 Gene
- HGNC(17025)
- Entrez Gene(81578)
- Ensembl(ENSG00000124749)
- OMIM(610002)
- UniProtKB(Q96P44)
- Open Targets Platform(ENSG00000124749)
- Monarch Initiative
- Search for COL21A1 at DataMed
- Search for COL21A1 at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for COL21A1 Gene
Genomics for COL21A1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for COL21A1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH06J056245 | Promoter/Enhancer | 1.9 | EPDnew Ensembl ENCODE CraniofacialAtlas | 608.9 | +147.3 | 147326 | 2.8 | CTCF TEAD4 PRDM10 PRDM1 ZIC2 PATZ1 ZNF501 ZNF600 KLF9 ZBTB20 | COL21A1 HSALNG0050778 L13714-388 BMP5 | |
| GH06J056394 | Promoter | 0.6 | EPDnew | 600.7 | 0.0 | -20 | 0.1 | MGA ZFHX2 EGR2 | COL21A1 RCC2P7 DST | |
| GH06J056231 | Enhancer | 0.6 | Ensembl ENCODE | 19.5 | +162.5 | 162508 | 3.2 | NFE2 MAFK JUN NFE2L2 CEBPB | COL21A1 KIAA1586 HSALNG0050778 L13714-388 BMP5 | |
| GH06J056220 | Enhancer | 0.7 | Ensembl ENCODE | 14.7 | +173.7 | 173727 | 1.6 | SP1 CTBP1 PKNOX1 ZNF217 FOSL2 DPF2 FOXA1 ZNF843 FEZF1 FOS | RF00017-5603 COL21A1 piR-55036-083 BMP5 | |
| GH06J056090 | Promoter/Enhancer | 1.1 | Ensembl ENCODE | 8.7 | +302.6 | 302616 | 1.6 | CEBPG GATAD2A ATF7 PRDM10 TFE3 FOXA1 RXRB CEBPA KMT2B SOX13 | lnc-BMP5-2 COL21A1 piR-38351-399 BMP5 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around COL21A1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for COL21A1
Genomic Locations for COL21A1 Gene
Genomic Locations for COL21A1 Gene
- chr6:56,056,590-56,394,128
- (GRCh38/hg38)
- Size:
- 337,539 bases
- Orientation:
- Minus strand
- chr6:55,921,388-56,258,892
- (GRCh37/hg19)
- Size:
- 337,505 bases
- Orientation:
- Minus strand
Genomic View for COL21A1 Gene
Genes around COL21A1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6p12.1 by HGNC
- 6p12.1|6p12.3-p11.2 by Entrez Gene
- 6p12.1 by Ensembl
COL21A1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for COL21A1 Gene
Proteins for COL21A1 Gene
-
Protein details for COL21A1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96P44-COLA1_HUMAN
- Recommended name:
- Collagen alpha-1(XXI) chain
- Protein Accession:
- Q96P44
- A6NIX5
- B2R8J9
- Q49A51
- Q71RF4
- Q8WXV8
- Q9H0V3
Protein attributes for COL21A1 Gene
- Size:
- 957 amino acids
- Molecular mass:
- 99369 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH45597.1; Type=Frameshift; Evidence={ECO:0000305};
Protein Expression for COL21A1 Gene
Post-translational modifications for COL21A1 Gene
Other Protein References for COL21A1 Gene
Antibody Products
- Novus Biologicals Antibodies for COL21A1
-
Abcam antibodies for COL21A1
- Invitrogen Antibodies for COL21A1 (AFLGC-COL21A1)
-
Biorbyt antibodies for COL21A1
Protein Products
- G Biosciences Human COL21A1/Collagen alpha-1(XXI) chain, Lyophilized
-
OriGene Purified Proteins for COL21A1
- Search Origene for MassSpec and Protein Over-expression Lysates for COL21A1
- Origene Custom Protein Services for COL21A1
- antibodies-online: Show 3 available COL21A1 Proteins ranked by validation data
- Compare Top COL21A1 Proteins
-
Quality Products:
-
Abcam proteins for COL21A1
No data available for DME Specific Peptides for COL21A1 Gene
Domains & Families for COL21A1 Gene
Gene Families for COL21A1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for COL21A1 Gene
- InterPro:
- Blocks:
-
- Collagen triple helix repeat
- Collagen helix repeat
- Von Willebrand factor type A domain signature
- Thrombospondin, N-terminal
- ProtoNet:
Suggested Antigen Peptide Sequences for COL21A1 Gene
- GenScript: Design optimal peptide antigens:
-
- Collagen type XXI alpha 1 (A6PVD8_HUMAN)
- COL21A1 protein (B7ZLK3_HUMAN)
- Collagen alpha-1(XXI) chain (COLA1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96P44UniProtKB/Swiss-Prot:
COLA1_HUMAN :- Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
- Family:
-
- Belongs to the fibril-associated collagens with interrupted helices (FACIT) family.
Function for COL21A1 Gene
Molecular function for COL21A1 Gene
- UniProtKB/Swiss-Prot Induction:
- Stimulated by PDGF/platelet-derived growth factor.
Phenotypes From GWAS Catalog for COL21A1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0030020 | extracellular matrix structural constituent conferring tensile strength | RCA | 20551380 |
Phenotypes for COL21A1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COL21A1 - Select products 50% OFF >
- * COL21A1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for COL21A1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL21A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL21A1
miRNA for COL21A1 Gene
- miRTarBase miRNAs that target COL21A1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COL21A1
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Clone Products
- Applied Biological Materials (abm): Clones for COL21A1 - Select products 50% OFF >
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- Sino Biological Human cDNA Clone for COL21A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL21A1
Cell Line Products
- ESI BIO PureStem SK11, NCr-fac & Meso-prx Progenitor for COL21A1
-
Horizon Cell Lines for COL21A1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for COL21A1 Gene
Localization for COL21A1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for COL21A1 Gene
- Secreted, extracellular space, extracellular matrix. Cytoplasm. Note=Found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| endoplasmic reticulum | 4 |
| cytosol | 4 |
| cytoskeleton | 2 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| nucleus | 1 |
| lysosome | 0 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005581 | collagen trimer | IEA | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
Pathways & Interactions for COL21A1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Collagen chain trimerization |
Intrinsic Prothrombin Activation Pathway
.48
Blood Coagulation Cascade
.46
|
|
| 2 | Integrin Pathway |
FAK1 Signaling
.67
Integrin Pathway
.67
GnRH Signaling
.56
|
UPA-UPAR Pathway
.56
Inhibition of Angiogenesis by TSP1
.50
Transendothelial Migration of Leukocytes
.38
|
| 3 | ERK Signaling |
ERK Signaling
.61
Rho Family GTPases
.61
MAPK Signaling
.58
|
Molecular Mechanisms of Cancer
.51
ILK Signaling
.49
|
| 4 | Phospholipase-C Pathway |
Phospholipase-C Pathway
.56
|
PTEN Pathway
.56
|
| 5 | Degradation of the extracellular matrix | ||
Pathways by source for COL21A1 Gene
4 Reactome pathways for COL21A1 Gene
1 KEGG pathway for COL21A1 Gene
15 Qiagen pathways for COL21A1 Gene
- Blood Coagulation Cascade
- ERK Signaling
- FAK1 Signaling
- GnRH Signaling
- ILK Signaling
Interacting Proteins for COL21A1 Gene
GPS-Prot Interaction Network for COL21A1
No data available for SIGNOR curated interactions for COL21A1 Gene
Drugs & Compounds for COL21A1 Gene
No Compound Related Data Available
Drug Products
- G Biosciences Human COL21A1/Collagen alpha-1(XXI) chain, Lyophilized
Transcripts for COL21A1 Gene
mRNA/cDNA for COL21A1 Gene
- 5 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000488912 2327 nts (view in UCSC)
- ENST00000244728 4173 nts (view in UCSC)
- ENST00000370819 4094 nts (view in UCSC)
- ENST00000467045 2291 nts (view in UCSC)
- ENST00000482933 1413 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for COL21A1 - Select products 50% OFF >
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- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for COL21A1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL21A1
-
Santa Cruz Biotechnology (SCBT) CRISPR for COL21A1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for COL21A1
- Browse OriGene Inhibitory RNA Products For COL21A1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COL21A1
Clone Products
- Applied Biological Materials (abm): Clones for COL21A1 - Select products 50% OFF >
- * COL21A1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for COL21A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL21A1
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||||
| SP7: |
Relevant External Links for COL21A1 Gene
- GeneLoc Exon Structure for
- COL21A1
Expression for COL21A1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- NULL (Uncategorized)
- Neural Crest (Gastrulation Derivatives)
- Paraxial Mesoderm (Gastrulation Derivatives)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for COL21A1 Gene
This gene is overexpressed in Artery - Aorta (x7.7) and Artery - Coronary (x4.7).
This gene is overexpressed in Spinal cord (14.9), Placenta (13.0), and Pancreatic juice (8.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for COL21A1 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for COL21A1
SOURCE GeneReport for Unigene cluster for COL21A1 Gene:
Hs.47629mRNA Expression by UniProt/SwissProt for COL21A1 Gene:
Q96P44-COLA1_HUMAN
Tissue specificity:
Highly expressed in lymph node, jejunum, pancreas, stomach, trachea, testis, uterus and placenta; moderately expressed in brain, colon, lung, prostate, spinal cord, salivary gland and vascular smooth-muscle cells and very weakly expressed in heart, liver, kidney, bone marrow, spleen, thymus, skeletal muscle, adrenal gland and peripheral leukocytes. Expression in heart was higher in the right ventricle and atrium than in the left ventricle and atrium.
Evidence on tissue expression from TISSUES for COL21A1 Gene
- Nervous system(4.4)
- Muscle(2.4)
- Heart(2.2)
Primer Products
-
OriGene qPCR primer pairs for COL21A1
Gene Expression Assay Products
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for COL21A1 Gene
Orthologs for COL21A1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | COL21A1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | COL21A1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | COL21A1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | COL21A1 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | COL21A1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | COL21A1 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | COL21A1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | col21a1 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | LOC100333837 30 |
|
||
| COL21A1 31 |
|
OneToOne | |||
| Worm (Caenorhabditis elegans) |
Secernentea | col-135 31 |
|
OneToMany |
- Species where no ortholog for COL21A1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Mouse (Mus musculus)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rat (Rattus norvegicus)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for COL21A1 Gene
- ENSEMBL:
- Gene Tree for COL21A1 (if available)
- TreeFam:
- Gene Tree for COL21A1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for COL21A1: view image
Paralogs for COL21A1 Gene
Paralogs for COL21A1 Gene
- COL18A1 5
- COL5A1 5
- COL11A1 5
- COL11A2 5
- COL16A1 5
- COL22A1 5
- COL5A3 5
- COL4A5 5
- COL3A1 5
- COL4A6 5
- COL4A3 5
- COL2A1 5
- COL1A1 5
- COL15A1 5
- COL4A2 5
- COL4A1 5
- COL7A1 5
- COL1A2 5
- COL4A4 5
- COL27A1 5
- COL5A2 5
- COL24A1 5
- COL9A1 5
- COL17A1 5
- COL28A1 5
- COL9A3 5
- COL6A2 5
- COL20A1 5
- COL25A1 5
- COL6A1 5
- COL23A1 5
- COL13A1 5
- COL9A2 5
- COLQ 5
- EMID1 5
- COL26A1 5
- EDA 5
(31) SIMAP similar genes for COL21A1 Gene using alignment to 6 proteins:
- COLA1_HUMAN
- A6PVD9_HUMAN
- B7ZLK3_HUMAN
- F5GZK2_HUMAN
- H0Y4C9_HUMAN
- H0YDH6_HUMAN
Variants for COL21A1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for COL21A1 Gene
| SNP ID | Clinical significance and condition | Chr 06 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 771399 | Benign: not provided | 56,059,169(-) | G/A | NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT | |
| 771715 | Benign: not provided | 56,124,072(-) | G/C | MISSENSE_VARIANT,NON_CODING_TRANSCRIPT_VARIANT | |
| rs12209452 | - | p.Leu821Pro | |||
| rs1555131 | - | p.Pro827Ala | |||
| rs2764043 | - | p.Leu277Pro |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv1388199 | CNV | deletion | 17803354 |
| esv2427713 | CNV | deletion | 19546169 |
| esv27231 | CNV | loss | 19812545 |
| esv2732118 | CNV | deletion | 23290073 |
| esv2732119 | CNV | deletion | 23290073 |
| esv3539781 | CNV | deletion | 23714750 |
| esv3571085 | CNV | loss | 25503493 |
| esv3571087 | CNV | loss | 25503493 |
| esv3609088 | CNV | loss | 21293372 |
| esv3609089 | CNV | loss | 21293372 |
| esv993486 | CNV | deletion | 20482838 |
| nsv1034037 | CNV | gain | 25217958 |
| nsv1074397 | CNV | deletion | 25765185 |
| nsv1117623 | CNV | deletion | 24896259 |
| nsv1140630 | CNV | deletion | 24896259 |
| nsv349404 | CNV | deletion | 16902084 |
| nsv477746 | CNV | novel sequence insertion | 20440878 |
| nsv526703 | CNV | loss | 19592680 |
| nsv5313 | CNV | insertion | 18451855 |
| nsv819041 | CNV | gain | 19587683 |
Residual Variation Intolerance Score:
58.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.82;
79.19% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for COL21A1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- COL21A1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for COL21A1 Gene
Disorders for COL21A1 Gene
Additional Disease Information for COL21A1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for COL21A1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for COL21A1 Gene
Publications for COL21A1 Gene
- A new FACIT of the collagen family: COL21A1. (PMID: 11566190) Fitzgerald J … Bateman JF (FEBS letters 2001) 2 3 4 23
- Genomic organization and characterization of the human type XXI collagen (COL21A1) gene. (PMID: 11863369) Chou MY … Li HC (Genomics 2002) 3 4 23
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 3 4
ExternalLinks
Products for COL21A1 Gene
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ESI BIO PureStem SK11, NCr-fac & Meso-prx Progenitor for COL21A1
- Invitrogen Antibodies for COL21A1 (AFLGC-COL21A1)
- VectorBuilder Custom and pre-made DNA vectors for COL21A1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for COL21A1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for COL21A1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for COL21A1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for COL21A1
- antibodies-online: Show 10 available COL21A1 Antibodies ranked by validation data
- Compare Top COL21A1 Antibodies
- antibodies-online: Search results for available COL21A1 related products ranked by validation data
- antibodies-online: Show 3 available COL21A1 Proteins ranked by validation data
- Compare Top COL21A1 Proteins
- Quality Products:
- Horizon Cell Lines for COL21A1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for COL21A1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for COL21A1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for COL21A1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for COL21A1
- Biorbyt antibodies for COL21A1
Sources for COL21A1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB