Aliases for COL16A1 Gene
External Ids for COL16A1 Gene
Previous GeneCards Identifiers for COL16A1 Gene
This gene encodes the alpha chain of type XVI collagen, a member of the FACIT collagen family (fibril-associated collagens with interrupted helices). Members of this collagen family are found in association with fibril-forming collagens such as type I and II, and serve to maintain the integrity of the extracellular matrix. High levels of type XVI collagen have been found in fibroblasts and keratinocytes, and in smooth muscle and amnion. [provided by RefSeq, Jul 2008]
GeneCards Summary for COL16A1 Gene
COL16A1 (Collagen Type XVI Alpha 1 Chain) is a Protein Coding gene. Among its related pathways are ERK Signaling and Collagen chain trimerization. Gene Ontology (GO) annotations related to this gene include integrin binding. An important paralog of this gene is COL4A5.
UniProtKB/Swiss-Prot for COL16A1 Gene
Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.