Aliases for CNTNAP4 Gene
External Ids for CNTNAP4 Gene
Previous GeneCards Identifiers for CNTNAP4 Gene
This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016]
GeneCards Summary for CNTNAP4 Gene
CNTNAP4 (Contactin Associated Protein Family Member 4) is a Protein Coding gene. Diseases associated with CNTNAP4 include Attention Deficit-Hyperactivity Disorder. An important paralog of this gene is ENSG00000287694.
UniProtKB/Swiss-Prot Summary for CNTNAP4 Gene
Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity).