Aliases for CNPY3 Gene
External Ids for CNPY3 Gene
Previous HGNC Symbols for CNPY3 Gene
Previous GeneCards Identifiers for CNPY3 Gene
This gene encodes a protein that binds members of the toll-like receptor protein family and functions as a chaperone to aid in folding and export of these proteins. Alternative splicing results in multiple transcript variants. Naturally occuring readthrough transcription occurs between this locus and the downstream GNMT (glycine N-methyltransferase) gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
GeneCards Summary for CNPY3 Gene
CNPY3 (Canopy FGF Signaling Regulator 3) is a Protein Coding gene. Diseases associated with CNPY3 include Swayback. Among its related pathways are Innate Immune System and Activated TLR4 signalling. Gene Ontology (GO) annotations related to this gene include receptor binding. An important paralog of this gene is CNPY4.
UniProtKB/Swiss-Prot for CNPY3 Gene
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).