Aliases for CNOT11 Gene
External Ids for CNOT11 Gene
Previous HGNC Symbols for CNOT11 Gene
Previous GeneCards Identifiers for CNOT11 Gene
GeneCards Summary for CNOT11 Gene
CNOT11 (CCR4-NOT Transcription Complex Subunit 11) is a Protein Coding gene. Diseases associated with CNOT11 include Wissler-Fanconi Syndrome and Fungal Esophagitis. Among its related pathways are Deadenylation-dependent mRNA decay and TP53 Regulates Transcription of Cell Cycle Genes.
UniProtKB/Swiss-Prot Summary for CNOT11 Gene
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.