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CNOT11 (CCR4-NOT Transcription Complex Subunit 11) is a Protein Coding gene. Diseases associated with CNOT11 include Wissler-Fanconi Syndrome and Fungal Esophagitis. Among its related pathways are Deadenylation-dependent mRNA decay and TP53 Regulates Transcription of Cell Cycle Genes.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003674 | molecular_function | ND | -- |
GO:0005515 | protein binding | IPI | 23232451 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005634 | nucleus | IEA | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005829 | cytosol | TAS | -- |
GO:0030014 | CCR4-NOT complex | IEA,IDA | 19558367 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Deadenylation-dependent mRNA decay | ||
2 | Gene Expression |
.48
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|
3 | TP53 Regulates Transcription of Cell Cycle Genes | ||
4 | Regulation of TP53 Activity |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening | TAS | -- |
GO:0006417 | regulation of translation | IEA | -- |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | TAS | -- |
GO:0031047 | gene silencing by RNA | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||||||||||||
SP2: | |||||||||||||||||||||
SP3: |
This gene was present in the common ancestor of eukaryotes.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CNOT11 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | CNOT11 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | CNOT11 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CNOT11 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Cnot11 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CNOT11 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Cnot11 30 |
|
||
Chicken (Gallus gallus) |
Aves | CNOT11 31 |
|
OneToOne | |
C2ORF29 30 |
|
||||
Lizard (Anolis carolinensis) |
Reptilia | CNOT11 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cnot11 30 |
|
||
Str.18681 30 |
|
||||
Zebrafish (Danio rerio) |
Actinopterygii | cnot11 30 31 |
|
OneToOne | |
wufj49e01 30 |
|
||||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.971 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG13567 30 31 |
|
OneToOne | |
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP007117 30 |
|
||
Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT5G18420 30 |
|
||
Alicante grape (Vitis vinifera) |
eudicotyledons | Vvi.5129 30 |
|
||
Soybean (Glycine max) |
eudicotyledons | Gma.17966 30 |
|
||
Rice (Oryza sativa) |
Liliopsida | Os11g0240900 30 |
|
||
Barley (Hordeum vulgare) |
Liliopsida | Hv.10531 30 |
|
||
Wheat (Triticum aestivum) |
Liliopsida | Ta.4129 30 |
|
||
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.605 31 |
|
OneToMany | |
-- 31 |
|
OneToMany | |||
Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.12100 30 |
|
Disorder | Aliases | PubMed IDs |
---|---|---|
wissler-fanconi syndrome |
|
|
fungal esophagitis |
|
|
plantar fasciitis |
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dermatographia |
|
|
rapidly progressive glomerulonephritis |
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|