Aliases for CNN3 Gene
External Ids for CNN3 Gene
Previous GeneCards Identifiers for CNN3 Gene
This gene encodes a protein with a markedly acidic C terminus; the basic N-terminus is highly homologous to the N-terminus of a related gene, CNN1. Members of the CNN gene family all contain similar tandemly repeated motifs. This encoded protein is associated with the cytoskeleton but is not involved in contraction. [provided by RefSeq, Jul 2008]
GeneCards Summary for CNN3 Gene
CNN3 (Calponin 3) is a Protein Coding gene. Diseases associated with CNN3 include Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN2.
UniProtKB/Swiss-Prot Summary for CNN3 Gene
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.