Aliases for CNN2 Gene
External Ids for CNN2 Gene
Previous GeneCards Identifiers for CNN2 Gene
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
GeneCards Summary for CNN2 Gene
CNN2 (Calponin 2) is a Protein Coding gene. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN3.
UniProtKB/Swiss-Prot Summary for CNN2 Gene
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.