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The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alter... See more...
Aliases for CNN2 Gene
Aliases for CNN2 Gene
External Ids for CNN2 Gene
- HGNC: 2156
- Entrez Gene: 1265
- Ensembl: ENSG00000064666
- OMIM: 602373
- UniProtKB: Q99439
Previous GeneCards Identifiers for CNN2 Gene
- GC19P001102
- GC19P000966
- GC19P000977
- GC19P000799
Summaries for CNN2 Gene
-
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and cell adhesion. Several pseudogenes of this gene have been identified, and are present on chromosomes 1, 2, 3, 6, 9, 11, 13, 15, 16, 21 and 22. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
GeneCards Summary for CNN2 Gene
CNN2 (Calponin 2) is a Protein Coding gene. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Innate Immune System. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN3.
UniProtKB/Swiss-Prot Summary for CNN2 Gene
-
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
Additional gene information for CNN2 Gene
- HGNC(2156)
- Entrez Gene(1265)
- Ensembl(ENSG00000064666)
- OMIM(602373)
- UniProtKB(Q99439)
- Open Targets Platform(ENSG00000064666)
- Monarch Initiative
- Search for CNN2 at DataMed
- Search for CNN2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CNN2 Gene
Genomics for CNN2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CNN2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CNN2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CNN2
- Top Transcription factor binding sites by QIAGEN in the CNN2 gene promoter:
-
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-2gamma
- Brachyury
- c-Myc
- COMP1
- Max1
- NRSF form 1
- NRSF form 2
Genomic Locations for CNN2 Gene
Genomic Locations for CNN2 Gene
- chr19:1,026,586-1,039,068
- (GRCh38/hg38)
- Size:
- 12,483 bases
- Orientation:
- Plus strand
- chr19:1,026,298-1,039,068
- (GRCh37/hg19)
- Size:
- 12,771 bases
- Orientation:
- Plus strand
Genomic View for CNN2 Gene
Genes around CNN2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.3 by HGNC
- 19p13.3 by Entrez Gene
- 19p13.3 by Ensembl
CNN2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CNN2 Gene
Proteins for CNN2 Gene
-
Protein details for CNN2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q99439-CNN2_HUMAN
- Recommended name:
- Calponin-2
- Protein Accession:
- Q99439
- A5D8U8
- A6NFI4
- D6W5X9
- Q92578
Protein attributes for CNN2 Gene
- Size:
- 309 amino acids
- Molecular mass:
- 33697 Da
- Quaternary structure:
- No Data Available
Protein Expression for CNN2 Gene
Post-translational modifications for CNN2 Gene
Other Protein References for CNN2 Gene
Antibody Products
- G Biosciences Immunotag™ CNN2 Antibody
-
Custom Antibody ServicesOriGene Antibodies for CNN2
- Novus Biologicals Antibodies for CNN2
- Invitrogen Antibodies for CNN2 (AFLGC-Cnn2)
- Sino Biological Antibodies for CNN2
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CNN2
- Origene Custom Protein Services for CNN2
- ProSpec Recombinant Proteins for CNN2
- antibodies-online: Show 10 available CNN2 Proteins ranked by validation data
- Compare Top CNN2 Proteins
-
Quality Products:
-
Abcam proteins for CNN2
Assay Products
- G Biosciences Immunotag™ Human CNN2 (Calponin-2) ELISA and Immunotag™ Calponin-2 ELISA Kit
- antibodies-online: Show 15 available CNN2 Elisa Kits ranked by validation data
- Compare Top CNN2 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for CNN2 Gene
Domains & Families for CNN2 Gene
Gene Families for CNN2 Gene
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for CNN2 Gene
- InterPro:
- Blocks:
-
- Calponin-like actin-binding
- Calponin signature
- Calponin-like actin-binding subtype
- ProtoNet:
Suggested Antigen Peptide Sequences for CNN2 Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ44427 fis, clone UTERU2007724, highly similar to Homo sapiens calponin 2 (CNN2), transcript variant 2, mRNA (A6NFI4_HUMAN)
- Neutral calponin (CNN2_HUMAN)
- CNN2 protein (Q6FHC3_HUMAN)
- Calponin 2 (Q6FHE4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q99439- Family:
-
- Belongs to the calponin family.
Function for CNN2 Gene
Molecular function for CNN2 Gene
- UniProtKB/Swiss-Prot Function:
- Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
- GENATLAS Biochemistry:
- calponin neutral,h2,cytoskeletal protein of smooth muscle cells,actin,calmodulin,tropomyosin binding,closely related to non-muscle calponin CNN3
Phenotypes From GWAS Catalog for CNN2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IEA | -- |
| GO:0005515 | protein binding | IEA | -- |
| GO:0005516 | calmodulin binding | IEA | -- |
| GO:0045296 | cadherin binding | HDA | 25468996 |
Phenotypes for CNN2 Gene
- MGI mutant phenotypes for CNN2:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for CNN2:
Animal Models for CNN2 Gene
- MGI Knock Outs for CNN2:
-
- Cnn2 Cnn2<tm1.2Jin>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CNN2 - Select products 50% OFF >
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-
OriGene CRISPR knockouts for CNN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CNN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNN2
miRNA for CNN2 Gene
- miRTarBase miRNAs that target CNN2
-
- dre-miR-1 (MIRT003654)
- hsa-miR-133a-3p (MIRT021704)
- hsa-miR-744-5p (MIRT037661)
- hsa-miR-346 (MIRT042725)
- hsa-miR-219b-3p (MIRT479104)
- hsa-miR-489-5p (MIRT479105)
- hsa-miR-6854-3p (MIRT479106)
- hsa-miR-140-3p (MIRT479107)
- hsa-miR-4257 (MIRT479108)
- hsa-miR-205-3p (MIRT479109)
- hsa-miR-329-5p (MIRT479110)
- hsa-miR-137 (MIRT479111)
- hsa-miR-133b (MIRT479112)
- hsa-miR-23a-3p (MIRT479113)
- hsa-miR-23b-3p (MIRT479114)
- hsa-miR-23c (MIRT479115)
- hsa-miR-130a-5p (MIRT479116)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CNN2
- Browse OriGene Inhibitory RNA Products For CNN2
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Clone Products
- Applied Biological Materials (abm): Clones for CNN2 - Select products 50% OFF >
- * CNN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
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- MG203003
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- RC212208
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- RC221104
- RC221104L1
- RC221104L2
- RC221104L3
- RC221104L4
- RG212208
- RG221104
- MR203003L3V
- MR203003L4V
- MR204286L3V
- MR204286L4V
- RC212208L3V
- RC212208L4V
- RC221104L1V
- RC221104L2V
- RC221104L3V
- RC221104L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CNN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CNN2
Cell Line Products
-
Horizon Cell Lines for CNN2
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CNN2 Gene
Localization for CNN2 Gene
| Compartment | Confidence |
|---|---|
| cytoskeleton | 5 |
| extracellular | 4 |
| cytosol | 4 |
| nucleus | 3 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
- Actin filaments (2)
- Cytosol (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001725 | stress fiber | IDA | 16236705 |
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005856 | cytoskeleton | IEA,TAS | 8889829 |
| GO:0005911 | cell-cell junction | TAS | 8889829 |
| GO:0005925 | focal adhesion | HDA | 21423176 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for CNN2 Gene
Pathways & Interactions for CNN2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
| 2 | Myometrial Relaxation and Contraction Pathways | ||
Pathways by source for CNN2 Gene
1 BioSystems pathway for CNN2 Gene
3 Reactome pathways for CNN2 Gene
Interacting Proteins for CNN2 Gene
GPS-Prot Interaction Network for CNN2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007010 | cytoskeleton organization | IEA,TAS | 8889829 |
| GO:0010628 | positive regulation of gene expression | IEA | -- |
| GO:0030097 | hemopoiesis | IEA | -- |
| GO:0030336 | negative regulation of cell migration | IEA | -- |
| GO:0031032 | actomyosin structure organization | IEA | -- |
No data available for SIGNOR curated interactions for CNN2 Gene
Transcripts for CNN2 Gene
mRNA/cDNA for CNN2 Gene
- 4 REFSEQ mRNAs :
- 24 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000263097 2149 nts (view in UCSC)
- ENST00000562015 563 nts (view in UCSC)
- ENST00000348419 2033 nts (view in UCSC)
- ENST00000565096 2109 nts (view in UCSC)
- ENST00000569352 731 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CNN2 - Select products 50% OFF >
- * CNN2 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CNN2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CNN2
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNN2
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CNN2
- Browse OriGene Inhibitory RNA Products For CNN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CNN2
Clone Products
- Applied Biological Materials (abm): Clones for CNN2 - Select products 50% OFF >
- * CNN2 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG203003
- MG204286
- MR203003
- MR203003L3
- MR203003L4
- MR204286
- MR204286L3
- MR204286L4
- RC212208
- RC212208L3
- RC212208L4
- RC221104
- RC221104L1
- RC221104L2
- RC221104L3
- RC221104L4
- RG212208
- RG221104
- MR203003L3V
- MR203003L4V
- MR204286L3V
- MR204286L4V
- RC212208L3V
- RC212208L4V
- RC221104L1V
- RC221104L2V
- RC221104L3V
- RC221104L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for CNN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CNN2
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||
| SP3: | - | - | - | ||||||||||||||||||
| SP4: | - | ||||||||||||||||||||
| SP5: | - |
Relevant External Links for CNN2 Gene
- GeneLoc Exon Structure for
- CNN2
Expression for CNN2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Heart (Cardiovascular System)
- Bone (Muscoskeletal System)
- Smooth Muscle (Muscoskeletal System)
- Epiblast (Early Embryonic Tissues)
-
Uterus (Reproductive System)
-
Prostate (Endocrine System)
-
Spleen (Hematopoietic System)
-
Thyroid (Endocrine System)
-
Gall Bladder (Hepatobiliary System)
-
Lung (Respiratory System)
-
Esophagus (Gastrointestinal Tract)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for CNN2 Gene
This gene is overexpressed in Whole Blood (x12.5).
This gene is overexpressed in Bone marrow stromal cell (8.8), Platelet (8.3), and Lymph node (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CNN2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CNN2
SOURCE GeneReport for Unigene cluster for CNN2 Gene:
Hs.651512mRNA Expression by UniProt/SwissProt for CNN2 Gene:
Q99439-CNN2_HUMAN
Tissue specificity:
Heart and smooth muscle.
Evidence on tissue expression from TISSUES for CNN2 Gene
- Blood(4.9)
- Nervous system(4.6)
- Heart(4.5)
- Skin(4)
- Lung(3.5)
- Kidney(3.3)
- Intestine(3)
- Spleen(2.8)
- Muscle(2.6)
- Liver(2.4)
- Bone marrow(2.4)
- Lymph node(2.4)
- Eye(2.4)
- Pancreas(2.1)
- Stomach(2)
Primer Products
-
OriGene qPCR primer pairs for CNN2
-
OriGene qPCR primer pairs and template standards for CNN2
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CNN2 Gene
Orthologs for CNN2 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Dog (Canis familiaris) |
Mammalia | CNN2 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cnn2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | CNN2 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CNN2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Cnn2 30 17 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CNN2 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CNN2 30 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cnn1 30 |
|
||
| Str.6304 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | cnn2-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | cnn2 30 31 |
|
OneToOne | |
| Dr.28235 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | Mp20 30 31 |
|
ManyToMany | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP012304 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | cpn-2 31 |
|
OneToMany | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SCP1 31 |
|
OneToMany | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.7148 31 |
|
OneToMany |
- Species where no ortholog for CNN2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chimpanzee (Pan troglodytes)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
Evolution for CNN2 Gene
- ENSEMBL:
- Gene Tree for CNN2 (if available)
- TreeFam:
- Gene Tree for CNN2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CNN2: view image
Paralogs for CNN2 Gene
(26) SIMAP similar genes for CNN2 Gene using alignment to 9 proteins:
- CNN2_HUMAN
- B4DDF4_HUMAN
- B4DUT8_HUMAN
- H3BQH0_HUMAN
- H3BVI6_HUMAN
- K7ES69_HUMAN
- Q6FHC3_HUMAN
- Q6FHE4_HUMAN
- U3KPS3_HUMAN
Pseudogenes.org Pseudogenes for CNN2 Gene
- PGOHUM00000290766
- PGOHUM00000292068
- PGOHUM00000292960
- PGOHUM00000293635
- PGOHUM00000296642
- PGOHUM00000297342
- PGOHUM00000297514
- PGOHUM00000298001
- PGOHUM00000298550
- PGOHUM00000298982
- PGOHUM00000301914
- PGOHUM00000303814
- PGOHUM00000303842
- PGOHUM00000303883
- PGOHUM00000303905
- PGOHUM00000304201
- PGOHUM00000304232
- PGOHUM00000304277
- PGOHUM00000304294
Variants for CNN2 Gene
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv135n111 | CNV | deletion | 26073780 |
| dgv136n111 | CNV | deletion | 26073780 |
| dgv486e201 | CNV | deletion | 23290073 |
| dgv487e201 | CNV | deletion | 23290073 |
| esv1006717 | CNV | loss | 20482838 |
| esv1680853 | CNV | deletion | 17803354 |
| esv2044506 | CNV | deletion | 18987734 |
| esv22453 | CNV | loss | 19812545 |
| esv2492823 | CNV | deletion | 19546169 |
| esv25790 | CNV | loss | 19812545 |
| esv2586842 | CNV | deletion | 19546169 |
| esv2677837 | CNV | deletion | 23128226 |
| esv2758743 | CNV | gain+loss | 17122850 |
| esv3102679 | CNV | deletion | 24192839 |
| esv3643383 | CNV | gain | 21293372 |
| nsv1143894 | CNV | deletion | 24896259 |
| nsv1160555 | CNV | deletion | 26073780 |
| nsv469845 | CNV | loss | 16826518 |
| nsv512556 | CNV | loss | 21212237 |
| nsv578188 | CNV | loss | 21841781 |
| nsv833704 | CNV | gain | 17160897 |
| nsv953938 | CNV | deletion | 24416366 |
| nsv960770 | CNV | duplication | 23825009 |
| nsv9662 | CNV | gain | 18304495 |
Residual Variation Intolerance Score:
40.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.88;
18.31% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CNN2 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CNN2 Gene
Disorders for CNN2 Gene
Additional Disease Information for CNN2
No disorders were found for CNN2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CNN2 Gene
Publications for CNN2 Gene
- Molecular cloning and characterization of human non-smooth muscle calponin. (PMID: 8889829) Masuda H … Takahashi K (Journal of biochemistry 1996) 2 3 4 23
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PMID: 12665801) Gevaert K … Vandekerckhove J (Nature biotechnology 2003) 3 4
- A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21. (PMID: 9001224) Kuromitsu J … Hayashizaki Y (Molecular and cellular biology 1997) 3 4
- BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion. (PMID: 31519766) Chan CJ … Melançon P (Molecular & cellular proteomics : MCP 2019) 3
ExternalLinks
Products for CNN2 Gene
- Custom Antibody ServicesOriGene Antibodies for CNN2
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for CNN2
- Origene Custom Protein Services for CNN2
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CNN2
- Browse OriGene Inhibitory RNA Products For CNN2
- OriGene qPCR primer pairs for CNN2
- OriGene qPCR primer pairs and template standards for CNN2
- OriGene CRISPR knockouts for CNN2
- MG203003
- MG204286
- MR203003
- MR203003L3
- MR203003L4
- MR204286
- MR204286L3
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- RC212208
- RC212208L3
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- RC212208L3V
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- RC221104L3V
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For CNN2
- Sino Biological Human cDNA Clone for CNN2
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for CNN2
- Browse Sino Biological Assays
- Browse Antibodies
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for CNN2
- Novus Biologicals proteins and lysates for CNN2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam proteins for CNN2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for CNN2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CNN2 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CNN2 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CNN2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CNN2
- antibodies-online: Show 36 available CNN2 Antibodies ranked by validation data
- Compare Top CNN2 Antibodies
- antibodies-online: Show 15 available CNN2 Elisa Kits ranked by validation data
- Compare Top CNN2 Elisa Kits
- Quality Products:
- antibodies-online: Show 10 available CNN2 Proteins ranked by validation data
- Compare Top CNN2 Proteins
- Quality Products:
- Horizon Cell Lines for CNN2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CNN2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CNN2
- Search GeneCopoeia for miRNA 3'UTR Target clone products for CNN2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CNN2
Sources for CNN2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84)