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CNN1 (Calponin 1) is a Protein Coding gene. Diseases associated with CNN1 include Infantile Digital Fibromatosis and Laryngeal Small Cell Carcinoma. Among its related pathways are Mesenchymal Stem Cells and Lineage-specific Markers and Myometrial Relaxation and Contraction Pathways. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN3.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003779 | actin binding | IEA | -- |
GO:0005515 | protein binding | IEA,IPI | 27107012 |
GO:0005516 | calmodulin binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005856 | cytoskeleton | IDA | 8616889 |
GO:0005925 | focal adhesion | HDA | 21423176 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Cytoskeletal Signaling | ||
2 | Mesenchymal Stem Cells and Lineage-specific Markers | ||
3 | Endothelin Pathways | ||
4 | Myometrial Relaxation and Contraction Pathways |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006940 | regulation of smooth muscle contraction | TAS | 14550641 |
GO:0031032 | actomyosin structure organization | IEA | -- |
GO:1904706 | negative regulation of vascular smooth muscle cell proliferation | IGI | 26315405 |
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | ||||||||||||||||||||||||||
SP2: | |||||||||||||||||||||||||||||||
SP3: | - | - | |||||||||||||||||||||||||||||
SP4: | - | ||||||||||||||||||||||||||||||
SP5: | - | - |
This gene was present in the common ancestor of animals and fungi.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CNN1 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
CNN1 30 |
|
||||
-- 31 |
|
OneToMany | |||
Oppossum (Monodelphis domestica) |
Mammalia | CNN1 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CNN1 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Cnn1 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Cnn1 30 |
|
||
Platypus (Ornithorhynchus anatinus) |
Mammalia | CNN1 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CNN1 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cnn2 30 |
|
||
Str.8537 30 |
|
||||
African clawed frog (Xenopus laevis) |
Amphibia | MGC68737 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | LOC572250 30 |
|
||
cnn1b 31 |
|
OneToMany | |||
cnn1a 31 |
|
OneToMany | |||
Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.8817 30 |
|
||
African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP000749 30 |
|
||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG5023 30 |
|
||
Chd64 32 |
|
|
|||
Mp20 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | cpn-2 31 |
|
OneToMany | |
Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | SCP1 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.7148 31 |
|
OneToMany |
Disorder | Aliases | PubMed IDs |
---|---|---|
infantile digital fibromatosis |
|
|
laryngeal small cell carcinoma |
|
|
subareolar duct papillomatosis |
|
|
nipple benign neoplasm |
|
|
corneal dystrophy, subepithelial mucinous |
|
|