Aliases for CNKSR1 Gene
External Ids for CNKSR1 Gene
Previous GeneCards Identifiers for CNKSR1 Gene
This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for CNKSR1 Gene
CNKSR1 (Connector Enhancer Of Kinase Suppressor Of Ras 1) is a Protein Coding gene. Among its related pathways are Signaling by moderate kinase activity BRAF mutants and RET signaling. Gene Ontology (GO) annotations related to this gene include kinase activity and protein binding, bridging. An important paralog of this gene is CNKSR2.
UniProtKB/Swiss-Prot for CNKSR1 Gene
May function as an adapter protein or regulator of Ras signaling pathways.