Aliases for CNIH3 Gene
Aliases for CNIH3 Gene
External Ids for CNIH3 Gene
- HGNC: 26802
- Entrez Gene: 149111
- Ensembl: ENSG00000143786
- UniProtKB: Q8TBE1
Previous GeneCards Identifiers for CNIH3 Gene
- GC01P221111
- GC01P222870
- GC01P224622
- GC01P195324
Summaries for CNIH3 Gene
GeneCards Summary for CNIH3 Gene
CNIH3 (Cornichon Family AMPA Receptor Auxiliary Protein 3) is a Protein Coding gene. Among its related pathways are Transport to the Golgi and subsequent modification and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include channel regulator activity. An important paralog of this gene is CNIH2.
UniProtKB/Swiss-Prot for CNIH3 Gene
-
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
Additional gene information for CNIH3 Gene
- Monarch Initiative
- Search for CNIH3 at DataMed
- Search for CNIH3 at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CNIH3 Gene
Genomics for CNIH3 Gene
GeneHancer (GH) Regulatory Elements for CNIH3 Gene
Promoters and enhancers for CNIH3 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CNIH3 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CNIH3 gene promoter:
-
- NF-AT
- NF-AT4
- NF-AT3
- NF-AT2
- NF-AT1
- FOXO4
- FOXJ2
- FOXJ2 (long isoform)
- HSF2
Regulatory Element Products
Genomic Locations for CNIH3 Gene
Genomic Locations for CNIH3 Gene
- chr1:224,434,660-224,740,567
- (GRCh38/hg38)
- Size:
- 305,908 bases
- Orientation:
- Plus strand
- chr1:224,622,362-224,928,251
- (GRCh37/hg19)
- Size:
- 305,890 bases
- Orientation:
- Plus strand
Genomic View for CNIH3 Gene
Genes around CNIH3 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q42.12 by Entrez Gene
- 1q42.12 by HGNC
- 1q42.12 by Ensembl
CNIH3 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CNIH3 Gene
Proteins for CNIH3 Gene
-
Protein details for CNIH3 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8TBE1-CNIH3_HUMAN
- Recommended name:
- Protein cornichon homolog 3
- Protein Accession:
- Q8TBE1
Protein attributes for CNIH3 Gene
- Size:
- 160 amino acids
- Molecular mass:
- 18976 Da
- Quaternary structure:
-
- Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity).
Protein Expression for CNIH3 Gene
Post-translational modifications for CNIH3 Gene
No Post-translational modifications
Other Protein References for CNIH3 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for CNIH3
-
Abcam antibodies for CNIH3
- Invitrogen Antibodies for CNIH3
- GeneTex CNIH3 Antibody for CNIH3
Protein Products
-
OriGene Purified Proteins for CNIH3
- Search Origene for MassSpec and Protein Over-expression Lysates for CNIH3
- Origene Custom Protein Services for CNIH3
- antibodies-online: Search results for 3 available CNIH3 Proteins ranked by validation data
- Compare Top CNIH3 Proteins
-
Quality Products:
- Search GeneTex for Proteins for CNIH3
-
Abcam proteins for CNIH3
Assay Products
No data available for DME Specific Peptides for CNIH3 Gene
Domains & Families for CNIH3 Gene
Gene Families for CNIH3 Gene
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Protein Domains for CNIH3 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CNIH3 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8TBE1- Family:
-
- Belongs to the cornichon family.
Function for CNIH3 Gene
Molecular function for CNIH3 Gene
- UniProtKB/Swiss-Prot Function:
- Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
Phenotypes From GWAS Catalog for CNIH3 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016247 | channel regulator activity | IEA | -- |
Phenotypes for CNIH3 Gene
- MGI mutant phenotypes for CNIH3:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CNIH3:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CNIH3
-
CRISPR Products
-
OriGene CRISPR knockouts for CNIH3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CNIH3
- genomics-online: gRNA clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- Applied Biological Materials CRISPR for CNIH3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNIH3
- GenScript: Design CRISPR guide RNA sequences for CNIH3
miRNA for CNIH3 Gene
- miRTarBase miRNAs that target CNIH3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CNIH3
- Browse OriGene Inhibitory RNA Products For CNIH3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CNIH3
- genomics-online: shRNA clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
Clone Products
- Sino Biological Human cDNA Clone for CNIH3
- VectorBuilder custom plasmid, inducible vectors for CNIH3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CNIH3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CNIH3
- genomics-online: cdna clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- orf clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- Applied Biological Materials Clones for CNIH3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for CNIH3
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CNIH3 Gene
Localization for CNIH3 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CNIH3 Gene
- Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of pyramidal cells). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endoplasmic reticulum | 4 |
| extracellular | 3 |
| golgi apparatus | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | TAS | -- |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0012507 | ER to Golgi transport vesicle membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CNIH3 Gene
Pathways & Interactions for CNIH3 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Transport to the Golgi and subsequent modification | ||
| 2 | Vesicle-mediated transport | ||
| 3 | Metabolism of proteins | ||
Pathways by source for CNIH3 Gene
Interacting Proteins for CNIH3 Gene
GPS-Prot Interaction Network for CNIH3
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006888 | ER to Golgi vesicle-mediated transport | TAS | -- |
| GO:0016192 | vesicle-mediated transport | IEA | -- |
| GO:0035249 | synaptic transmission, glutamatergic | IEA | -- |
| GO:0042391 | regulation of membrane potential | IEA | -- |
| GO:0048208 | COPII vesicle coating | TAS | -- |
No data available for SIGNOR curated interactions for CNIH3 Gene
Transcripts for CNIH3 Gene
mRNA/cDNA for CNIH3 Gene
- (5) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (80) Selected AceView cDNA sequences:
- (14) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000471578 876 bps (uc057pve.1)
- ENST00000483512 968 bps (uc057pvf.1)
- ENST00000498126 778 bps (uc057pvg.1)
- ENST00000496372 451 bps (uc057pvh.1)
- ENST00000470602 389 bps (uc057pvi.1)
Unigene Clusters for CNIH3 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CNIH3
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CNIH3
- genomics-online: gRNA clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- Applied Biological Materials CRISPR for CNIH3
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNIH3
- GenScript: Design CRISPR guide RNA sequences for CNIH3
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CNIH3
- Browse OriGene Inhibitory RNA Products For CNIH3
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CNIH3
- genomics-online: shRNA clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
Clone Products
- Sino Biological Human cDNA Clone for CNIH3
- VectorBuilder custom plasmid, inducible vectors for CNIH3
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CNIH3
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CNIH3
- genomics-online: cdna clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- orf clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- Applied Biological Materials Clones for CNIH3
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for CNIH3 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
- Eye (Sensory Organs)
-
Spinal Cord (Nervous System)
mRNA differential expression in normal tissues according to GTEx for CNIH3 Gene
This gene is overexpressed in Brain - Frontal Cortex (BA9) (x5.0), Brain - Anterior cingulate cortex (BA24) (x5.0), Brain - Cortex (x4.7), and Brain - Hippocampus (x4.2).
This gene is overexpressed in Pancreas (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CNIH3 Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of CNIH3 Gene:
CNIH3SOURCE GeneReport for Unigene cluster for CNIH3 Gene:
Hs.731723mRNA Expression by UniProt/SwissProt for CNIH3 Gene:
Q8TBE1-CNIH3_HUMAN
Tissue specificity:
Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
Evidence on tissue expression from TISSUES for CNIH3 Gene
- Lung(4.1)
- Nervous system(4)
Primer Products
-
OriGene qPCR primer pairs and template standards for CNIH3
-
OriGene qPCR primer pairs for CNIH3
- genomics-online: primer clones - Search results for 107 available CNIH3 gene related products
- Overview of 107 available CNIH3 gene related products
-
Recommended
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
- pCMV6-Entry
- pCMV6-XL5
- pcDNA3.1+C-(K)-DYK
- pLenti-C-Myc-DDK
- pLenti-C-mGFP
- pDONR223
- pLenti-U6-sgRNA-PGK-Neo
- pLenti-U6-sgRNA-SFFV-Cas9-2A-Puro
- pPB-His-GST
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for CNIH3 Gene
Orthologs for CNIH3 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| oppossum (Monodelphis domestica) |
Mammalia | CNIH3 34 |
|
OneToOne | |
| chimpanzee (Pan troglodytes) |
Mammalia | CNIH3 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CNIH3 34 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | CNIH3 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Cnih3 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Cnih3 16 34 33 |
|
||
| dog (Canis familiaris) |
Mammalia | CNIH3 34 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CNIH3 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | CNIH3 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cnih3 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cnih3 34 33 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | cni 34 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | cni-1 34 |
|
ManyToMany | |
| Y64H9A.1 34 |
|
ManyToMany | |||
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | ERV14 34 |
|
ManyToMany | |
| ERV15 34 |
|
ManyToMany | |||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.5635 34 |
|
OneToMany |
- Species where no ortholog for CNIH3 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Evolution for CNIH3 Gene
- ENSEMBL:
- Gene Tree for CNIH3 (if available)
- TreeFam:
- Gene Tree for CNIH3 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CNIH3: view image
Paralogs for CNIH3 Gene
Variants for CNIH3 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs796052210 | uncertain-significance, Long QT syndrome | 224,434,047(+) | C/T | upstream_transcript_variant | |
| rs1000000663 | -- | 224,529,421(+) | G/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000011439 | -- | 224,493,211(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000016082 | -- | 224,648,609(+) | T/G | intron_variant | |
| rs1000031254 | -- | 224,628,005(+) | A/C | intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv102n67 | CNV | loss | 20364138 |
| esv24936 | CNV | gain | 19812545 |
| esv26044 | CNV | loss | 19812545 |
| esv2670242 | CNV | deletion | 23128226 |
| esv2723761 | CNV | deletion | 23290073 |
| esv3588977 | CNV | loss | 21293372 |
| nsv474794 | CNV | novel sequence insertion | 20440878 |
| nsv524125 | CNV | gain | 19592680 |
| nsv549261 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
57.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.47;
10.23% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CNIH3 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CNIH3
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CNIH3 Gene
Disorders for CNIH3 Gene
Additional Disease Information for CNIH3
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for CNIH3 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CNIH3 Gene
Publications for CNIH3 Gene
- Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia. (PMID: 23103966) Drummond JB … Meador-Woodruff JH (Neuroreport 2012) 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating. (PMID: 20805473) Shi Y … Nicoll RA (Proceedings of the National Academy of Sciences of the United States of America 2010) 3 4 58
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
Products for CNIH3 Gene
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- VectorBuilder custom plasmid, inducible vectors for CNIH3
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- Mammalian expression: PiggyBac
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- antibodies-online: Search results for 46 available CNIH3 Antibodies ranked by validation data
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- genomics-online: shRNA clones - Search results for 107 available CNIH3 gene related products
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Sources for CNIH3 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
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- (8) Gene Wiki
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- (68) Cloud-Clone Corp.
- (69) OCA
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- (74) GeneGo (Thomson Reuters)
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