Aliases for CMTR2 Gene
External Ids for CMTR2 Gene
Previous HGNC Symbols for CMTR2 Gene
GeneCards Summary for CMTR2 Gene
CMTR2 (Cap Methyltransferase 2) is a Protein Coding gene. Among its related pathways are Pathways Affected in Adenoid Cystic Carcinoma. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and mRNA (nucleoside-2-O-)-methyltransferase activity. An important paralog of this gene is CMTR1.
UniProtKB/Swiss-Prot for CMTR2 Gene
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap2 2-O-ribose methylation to the 5-cap structure of mRNAs. Methylates the ribose of the second nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) (cap0) to produce m(7)GpppRmpNm (cap2). Recognizes a guanosine cap on RNA independently of its N(7) methylation status. Display cap2 methylation on both cap0 and cap1. Displays a preference for cap1 RNAs.