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This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008] See more...
Aliases for CMTM6 Gene
Aliases for CMTM6 Gene
External Ids for CMTM6 Gene
- HGNC: 19177
- Entrez Gene: 54918
- Ensembl: ENSG00000091317
- OMIM: 607889
- UniProtKB: Q9NX76
Previous HGNC Symbols for CMTM6 Gene
- CKLFSF6
Summaries for CMTM6 Gene
-
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown. [provided by RefSeq, Jul 2008]
GeneCards Summary for CMTM6 Gene
CMTM6 (CKLF Like MARVEL Transmembrane Domain Containing 6) is a Protein Coding gene. Among its related pathways are Innate Immune System. Gene Ontology (GO) annotations related to this gene include cytokine activity. An important paralog of this gene is CMTM4.
UniProtKB/Swiss-Prot Summary for CMTM6 Gene
-
Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Additional gene information for CMTM6 Gene
- HGNC(19177)
- Entrez Gene(54918)
- Ensembl(ENSG00000091317)
- OMIM(607889)
- UniProtKB(Q9NX76)
- Open Targets Platform(ENSG00000091317)
- Search for CMTM6 at DataMed
- Search for CMTM6 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CMTM6 Gene
Genomics for CMTM6 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for CMTM6 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around CMTM6 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CMTM6
- Top Transcription factor binding sites by QIAGEN in the CMTM6 gene promoter:
-
- C/EBPalpha
- CP2
- FOXL1
- NF-kappaB
- NF-kappaB1
- RelA
- RORalpha1
- SRF
- SRF (504 AA)
Genomic Locations for CMTM6 Gene
Genomic Locations for CMTM6 Gene
- chr3:32,481,312-32,502,852
- (GRCh38/hg38)
- Size:
- 21,541 bases
- Orientation:
- Minus strand
- chr3:32,522,804-32,544,900
- (GRCh37/hg19)
- Size:
- 22,097 bases
- Orientation:
- Minus strand
Genomic View for CMTM6 Gene
Genes around CMTM6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 3p22.3 by HGNC
- 3p22.3 by Entrez Gene
- 3p22.3 by Ensembl
CMTM6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CMTM6 Gene
Proteins for CMTM6 Gene
-
Protein details for CMTM6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NX76-CKLF6_HUMAN
- Recommended name:
- CKLF-like MARVEL transmembrane domain-containing protein 6
- Protein Accession:
- Q9NX76
- Q6IAC4
Protein attributes for CMTM6 Gene
- Size:
- 183 amino acids
- Molecular mass:
- 20419 Da
- Quaternary structure:
-
- Interacts with PD-L1/CD274 (via transmembrane domain); the interaction is direct (PubMed:28813417, PubMed:28813410). Interacts with CMTM4 (PubMed:28813410). Interacts with CD58, ARG1, ENO1 and TMPO (PubMed:28813417).
Protein Expression for CMTM6 Gene
Post-translational modifications for CMTM6 Gene
Other Protein References for CMTM6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ CKLF6 Antibody
- GeneTex Anti-CMTM6 antibody [C1C3]
- Novus Biologicals Antibodies for CMTM6
-
Abcam antibodies for CMTM6
- Invitrogen Antibodies for CMTM6 (AFLGC-CMTM6)
-
Biorbyt antibodies for CMTM6
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for CMTM6
- Origene Custom Protein Services for CMTM6
- antibodies-online: Show 6 available CMTM6 Proteins ranked by validation data
- Compare Top CMTM6 Proteins
-
Quality Products:
No data available for DME Specific Peptides for CMTM6 Gene
Domains & Families for CMTM6 Gene
Gene Families for CMTM6 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
Suggested Antigen Peptide Sequences for CMTM6 Gene
- GenScript: Design optimal peptide antigens:
-
- Chemokine-like factor superfamily member 6 (CKLF6_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9NX76- Family:
-
- Belongs to the chemokine-like factor family.
Function for CMTM6 Gene
Molecular function for CMTM6 Gene
- UniProtKB/Swiss-Prot Function:
- Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.
Phenotypes From GWAS Catalog for CMTM6 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 28813410 |
Phenotypes for CMTM6 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CMTM6 - Select products 50% OFF >
- * CMTM6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for CMTM6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CMTM6
-
Santa Cruz Biotechnology (SCBT) CRISPR for CMTM6
miRNA for CMTM6 Gene
- miRTarBase miRNAs that target CMTM6
-
- mmu-miR-301b-3p (MIRT007965)
- mmu-miR-340-5p (MIRT010611)
- mmu-miR-15a-5p (MIRT011824)
- mmu-miR-19b-3p (MIRT012471)
- mmu-miR-24-3p (MIRT013992)
- mmu-miR-124-3p (MIRT015916)
- hsa-miR-378a-3p (MIRT019660)
- hsa-miR-128-3p (MIRT021869)
- hsa-miR-215-5p (MIRT024261)
- hsa-miR-192-5p (MIRT026194)
- hsa-miR-26b-5p (MIRT029005)
- hsa-miR-92a-3p (MIRT049092)
- hsa-miR-2681-5p (MIRT448135)
- hsa-miR-489-3p (MIRT448137)
- hsa-miR-3913-3p (MIRT448138)
- hsa-miR-378a-5p (MIRT532735)
- hsa-miR-6831-3p (MIRT532736)
- hsa-miR-215-3p (MIRT532737)
- hsa-miR-6773-3p (MIRT532738)
- hsa-miR-629-3p (MIRT532739)
- hsa-miR-4279 (MIRT532740)
- hsa-miR-6749-3p (MIRT532741)
- hsa-miR-1260b (MIRT532742)
- hsa-miR-1260a (MIRT532743)
- hsa-miR-532-3p (MIRT532744)
- hsa-miR-136-5p (MIRT532745)
- hsa-miR-660-3p (MIRT532746)
- hsa-miR-5193 (MIRT532747)
- hsa-miR-1224-3p (MIRT532748)
- hsa-miR-8063 (MIRT532749)
- hsa-miR-4477b (MIRT574299)
- hsa-miR-101-3p (MIRT574300)
- hsa-miR-4490 (MIRT574301)
- hsa-miR-3148 (MIRT574302)
- hsa-miR-545-5p (MIRT574303)
- hsa-miR-144-3p (MIRT574304)
- hsa-miR-1277-5p (MIRT574305)
- hsa-miR-651-3p (MIRT574306)
- hsa-miR-548z (MIRT574307)
- hsa-miR-548h-3p (MIRT574308)
- hsa-miR-548d-3p (MIRT574309)
- hsa-miR-548bb-3p (MIRT574310)
- hsa-miR-548ac (MIRT574311)
- mmu-miR-331-3p (MIRT584251)
- mmu-miR-5114 (MIRT584252)
- mmu-miR-185-5p (MIRT584253)
- mmu-miR-882 (MIRT584254)
- mmu-miR-3473a (MIRT584255)
- hsa-miR-134-5p (MIRT790109)
- hsa-miR-16-2-3p (MIRT790129)
- hsa-miR-195-3p (MIRT790150)
- hsa-miR-3118 (MIRT790226)
- hsa-miR-3136-5p (MIRT790235)
- hsa-miR-3161 (MIRT790247)
- hsa-miR-338-5p (MIRT790292)
- hsa-miR-4439 (MIRT790449)
- hsa-miR-4513 (MIRT790508)
- hsa-miR-599 (MIRT790803)
- hsa-miR-642a-3p (MIRT790842)
- hsa-miR-642b-3p (MIRT790843)
- hsa-miR-6730-3p (MIRT790898)
- hsa-miR-6855-3p (MIRT791033)
- hsa-miR-6857-3p (MIRT791038)
- hsa-miR-888-3p (MIRT791147)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CMTM6
- Browse OriGene Inhibitory RNA Products For CMTM6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CMTM6
Clone Products
- Applied Biological Materials (abm): Clones for CMTM6 - Select products 50% OFF >
- * CMTM6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CMTM6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CMTM6
Cell Line Products
-
Horizon Cell Lines for CMTM6
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CMTM6 Gene
Localization for CMTM6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CMTM6 Gene
- Cell membrane. Multi-pass membrane protein. Early endosome membrane. Multi-pass membrane protein. Recycling endosome membrane. Multi-pass membrane protein. Note=Co-localizes with PD-L1/CD274 in the plasma membrane and in recycling endosomes. {ECO:0000269 PubMed:28813417}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endosome | 5 |
| lysosome | 4 |
| cytosol | 2 |
| extracellular | 1 |
| cytoskeleton | 1 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
- Vesicles (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005768 | endosome | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | HDA | 19946888 |
| GO:0016021 | integral component of membrane | IBA | 21873635 |
| GO:0031901 | early endosome membrane | IEA,IDA | 28813417 |
Pathways & Interactions for CMTM6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Innate Immune System |
.61
|
|
Pathways by source for CMTM6 Gene
3 Reactome pathways for CMTM6 Gene
Interacting Proteins for CMTM6 Gene
Selected Interacting proteins:
Q9NX76-CKLF6_HUMAN
ENSP00000205636
for CMTM6 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for CMTM6
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0015031 | protein transport | IMP | 28813417 |
| GO:0031647 | regulation of protein stability | IMP | 28813410 |
| GO:0032456 | endocytic recycling | IMP | 28813417 |
| GO:0043312 | neutrophil degranulation | TAS | -- |
No data available for SIGNOR curated interactions for CMTM6 Gene
Transcripts for CMTM6 Gene
mRNA/cDNA for CMTM6 Gene
- 1 REFSEQ mRNAs :
- 9 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000205636 3307 nts (view in UCSC)
- ENST00000478886 803 nts (view in UCSC)
- ENST00000495177 670 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for CMTM6 - Select products 50% OFF >
- * CMTM6 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for CMTM6
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CMTM6
-
Santa Cruz Biotechnology (SCBT) CRISPR for CMTM6
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for CMTM6
- Browse OriGene Inhibitory RNA Products For CMTM6
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CMTM6
Clone Products
- Applied Biological Materials (abm): Clones for CMTM6 - Select products 50% OFF >
- * CMTM6 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for CMTM6
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CMTM6
Relevant External Links for CMTM6 Gene
- GeneLoc Exon Structure for
- CMTM6
Expression for CMTM6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
mRNA differential expression in normal tissues according to GTEx for CMTM6 Gene
This gene is overexpressed in Whole Blood (x5.9).
This gene is overexpressed in Monocytes (26.7), Bone (9.2), and Peripheral blood mononuclear cells (9.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CMTM6 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CMTM6
SOURCE GeneReport for Unigene cluster for CMTM6 Gene:
Hs.380627mRNA Expression by UniProt/SwissProt for CMTM6 Gene:
Q9NX76-CKLF6_HUMAN
Tissue specificity:
Expressed in the leukocytes, placenta and testis.
Evidence on tissue expression from TISSUES for CMTM6 Gene
- Blood(4.6)
- Spleen(2.6)
- Nervous system(2.5)
- Lymph node(2.3)
- Liver(2.3)
- Pancreas(2.3)
- Intestine(2.2)
- Skin(2.1)
- Lung(2)
Primer Products
-
OriGene qPCR primer pairs for CMTM6
-
OriGene qPCR primer pairs and template standards for CMTM6
Gene Expression Assay Products
No data available for Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for CMTM6 Gene
Orthologs for CMTM6 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | CMTM6 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | CMTM6 30 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Cmtm6 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Cmtm6 30 17 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | CMTM6 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | CMTM6 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | CMTM6 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | CMTM6 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | CMTM6 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | cmtm6 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | cmtm6 30 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.2454 31 |
|
OneToMany |
- Species where no ortholog for CMTM6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for CMTM6 Gene
- ENSEMBL:
- Gene Tree for CMTM6 (if available)
- TreeFam:
- Gene Tree for CMTM6 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CMTM6: view image
Paralogs for CMTM6 Gene
Paralogs for CMTM6 Gene
(1) SIMAP similar genes for CMTM6 Gene using alignment to 1 proteins:
- CKLF6_HUMAN
Pseudogenes.org Pseudogenes for CMTM6 Gene
Variants for CMTM6 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CMTM6 Gene
| SNP ID | Clinical significance and condition | Chr 03 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs35574803 | - | p.Thr91Ala |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3595776 | CNV | loss | 21293372 |
| nsv1003285 | CNV | gain | 25217958 |
| nsv834652 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
60.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.54;
29.91% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CMTM6 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CMTM6
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CMTM6 Gene
Disorders for CMTM6 Gene
Additional Disease Information for CMTM6
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No disorders were found for CMTM6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CMTM6 Gene
Publications for CMTM6 Gene
- CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. (PMID: 28813417) Burr ML … Dawson MA (Nature 2017) 3 4
- Identification of CMTM6 and CMTM4 as PD-L1 protein regulators. (PMID: 28813410) Mezzadra R … Schumacher TNM (Nature 2017) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. (PMID: 12782130) Han W … Ma D (Genomics 2003) 3 4
ExternalLinks
Products for CMTM6 Gene
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- OriGene qPCR primer pairs for CMTM6
- OriGene qPCR primer pairs and template standards for CMTM6
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- Sino Biological Human cDNA Clone for CMTM6
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- High-throughput Antibody Production Service
- Protein Production Service
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- Browse Antibodies
- Browse Peptides and Proteins
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- Browse ELISA Kits
- Abcam antibodies for CMTM6
- Find your target
- Browse Primary Antibodies
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- Invitrogen Antibodies for CMTM6 (AFLGC-CMTM6)
- VectorBuilder Custom and pre-made DNA vectors for CMTM6 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for CMTM6 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for CMTM6 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for CMTM6 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for CMTM6
- antibodies-online: Show 7 available CMTM6 Antibodies ranked by validation data
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- antibodies-online: Show 41 available CMTM6 Elisa Kits ranked by validation data
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- antibodies-online: Show 6 available CMTM6 Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for CMTM6
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CMTM6
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- Biorbyt antibodies for CMTM6
- Signalway ELISA kits for CMTM6
Sources for CMTM6 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
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