This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012] See more...

Aliases for CMPK1 Gene

Aliases for CMPK1 Gene

  • Cytidine/Uridine Monophosphate Kinase 1 2 3 5
  • UMP-CMP Kinase 2 3 4
  • UMP/CMP Kinase 2 3 4
  • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic 2 3
  • Uridine Monophosphate/Cytidine Monophosphate Kinase 3 4
  • Nucleoside-Diphosphate Kinase 3 4
  • Deoxycytidylate Kinase 3 4
  • Cytidylate Kinase 2 3
  • DCMP Kinase 3 4
  • EC 2.7.4.14 4 51
  • UMP-CMPK 2 3
  • CMPK 3 4
  • UMPK 3 4
  • CMK 3 4
  • UMK 3 4
  • CK 3 4
  • Cytidine Monophosphate Kinase 2
  • Uridine Monophosphate Kinase 3
  • EC 2.7.4.6 4
  • UMP/CMPK 4
  • EC 2.7.4 51
  • CMPK1 5
  • UCK 4

External Ids for CMPK1 Gene

Previous HGNC Symbols for CMPK1 Gene

  • CMPK

Previous GeneCards Identifiers for CMPK1 Gene

  • GC01P047572
  • GC01P047799
  • GC01P045915

Summaries for CMPK1 Gene

Entrez Gene Summary for CMPK1 Gene

  • This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]

GeneCards Summary for CMPK1 Gene

CMPK1 (Cytidine/Uridine Monophosphate Kinase 1) is a Protein Coding gene. Diseases associated with CMPK1 include Astrakhan Spotted Fever and Nemaline Myopathy 2. Among its related pathways are superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis and Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics. Gene Ontology (GO) annotations related to this gene include kinase activity and nucleobase-containing compound kinase activity. An important paralog of this gene is AK1.

UniProtKB/Swiss-Prot Summary for CMPK1 Gene

  • Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.

Gene Wiki entry for CMPK1 Gene

Additional gene information for CMPK1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CMPK1 Gene

Genomics for CMPK1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CMPK1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CMPK1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CMPK1

Top Transcription factor binding sites by QIAGEN in the CMPK1 gene promoter:
  • c-Myb
  • c-Rel
  • E2F
  • E2F-1
  • E2F-2
  • E2F-3a
  • E2F-4
  • E2F-5
  • FOXC1
  • RORalpha2

Genomic Locations for CMPK1 Gene

Genomic Locations for CMPK1 Gene
chr1:47,333,790-47,378,839
(GRCh38/hg38)
Size:
45,050 bases
Orientation:
Plus strand
chr1:47,799,469-47,844,511
(GRCh37/hg19)
Size:
45,043 bases
Orientation:
Plus strand

Genomic View for CMPK1 Gene

Genes around CMPK1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CMPK1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CMPK1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CMPK1 Gene

Proteins for CMPK1 Gene

  • Protein details for CMPK1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P30085-KCY_HUMAN
    Recommended name:
    UMP-CMP kinase
    Protein Accession:
    P30085
    Secondary Accessions:
    • B2R6S5
    • B4DPU7
    • E9PGI8
    • Q53GB7
    • Q5SVZ0
    • Q96C07
    • Q9UBQ8
    • Q9UIA2

    Protein attributes for CMPK1 Gene

    Size:
    196 amino acids
    Molecular mass:
    22222 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Quaternary structure:
    • Monomer.
    SequenceCaution:
    • Sequence=BAG60709.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
    Miscellaneous:
    • [Isoform 3]: May be produced from an in-frame upstream initiation codon. However, experimental evidence indicates that use of the downstream initiation codon is more likely (isoform 1 sequence).

    Three dimensional structures from OCA and Proteopedia for CMPK1 Gene

    Alternative splice isoforms for CMPK1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CMPK1 Gene

Selected DME Specific Peptides for CMPK1 Gene

P30085:
  • YIKEGKIVPV
  • GKADVSFVLFFDC
  • VVFVLGGPGAGKGTQC
  • DASKSVDEVF
  • YGYTHLS
  • PGAGKGT
  • SGRSDDN
  • IVPVEITISLL
  • MDGKADV
  • KFLIDGFPRN
  • LLRDERK
  • SQYGELI
  • MDQTMAAN
  • RCLERGKSSGR

Post-translational modifications for CMPK1 Gene

  • Ubiquitination at Lys26, Lys88, Lys43, Lys55, and Lys106
  • Modification sites at PhosphoSitePlus

Other Protein References for CMPK1 Gene

Domains & Families for CMPK1 Gene

Gene Families for CMPK1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for CMPK1 Gene

InterPro:
Blocks:
  • Adenylate kinase
ProtoNet:

Suggested Antigen Peptide Sequences for CMPK1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA, FLJ93091, Homo sapiens UMP-CMP kinase (UMP-CMPK), mRNA (B2R6S5_HUMAN)
  • Uridine monophosphate/cytidine monophosphate kinase (KCY_HUMAN)
  • Cytidine monophosphate (UMP-CMP) kinase 1, cytosolic (Q5T0D3_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P30085

UniProtKB/Swiss-Prot:

KCY_HUMAN :
  • Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
  • Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
Domain:
  • Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
Family:
  • Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
genes like me logo Genes that share domains with CMPK1: view

Function for CMPK1 Gene

Molecular function for CMPK1 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + CMP = ADP + CDP; Xref=Rhea:RHEA:11600, ChEBI:CHEBI:30616, ChEBI:CHEBI:58069, ChEBI:CHEBI:60377, ChEBI:CHEBI:456216; EC=2.7.4.14; Evidence={ECO:0000255|HAMAP-Rule:MF_03172};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + dCMP = ADP + dCDP; Xref=Rhea:RHEA:25094, ChEBI:CHEBI:30616, ChEBI:CHEBI:57566, ChEBI:CHEBI:58593, ChEBI:CHEBI:456216; EC=2.7.4.14; Evidence={ECO:0000255|HAMAP-Rule:MF_03172};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + UMP = ADP + UDP; Xref=Rhea:RHEA:24400, ChEBI:CHEBI:30616, ChEBI:CHEBI:57865, ChEBI:CHEBI:58223, ChEBI:CHEBI:456216; EC=2.7.4.14; Evidence={ECO:0000255|HAMAP-Rule:MF_03172};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP; Xref=Rhea:RHEA:44640, ChEBI:CHEBI:30616, ChEBI:CHEBI:61560, ChEBI:CHEBI:73316, ChEBI:CHEBI:456216; EC=2.7.4.6; Evidence={ECO:0000255|HAMAP-Rule:MF_03172};.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP; Xref=Rhea:RHEA:18113, ChEBI:CHEBI:30616, ChEBI:CHEBI:57930, ChEBI:CHEBI:61557, ChEBI:CHEBI:456216; EC=2.7.4.6; Evidence={ECO:0000255|HAMAP-Rule:MF_03172};.

Enzyme Numbers (IUBMB) for CMPK1 Gene

Phenotypes From GWAS Catalog for CMPK1 Gene

Gene Ontology (GO) - Molecular Function for CMPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0004127 cytidylate kinase activity IEA,IBA 21873635
GO:0004550 nucleoside diphosphate kinase activity IEA,IDA 23416111
GO:0004849 uridine kinase activity TAS 10462544
GO:0005524 ATP binding IEA --
genes like me logo Genes that share ontologies with CMPK1: view
genes like me logo Genes that share phenotypes with CMPK1: view

Animal Models for CMPK1 Gene

MGI Knock Outs for CMPK1:
  • Cmpk1 Cmpk1<tm1b(EUCOMM)Wtsi>

Animal Model Products

  • Taconic Biosciences Mouse Models for CMPK1

CRISPR Products

miRNA for CMPK1 Gene

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CMPK1

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CMPK1 Gene

Localization for CMPK1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CMPK1 Gene

Nucleus. Cytoplasm. Note=Predominantly cytoplasmic, less than 15% nuclear. {ECO:0000269 PubMed:11912132}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CMPK1 gene
Compartment Confidence
nucleus 5
extracellular 4
cytosol 4
mitochondrion 2
plasma membrane 1
cytoskeleton 1
endoplasmic reticulum 1
golgi apparatus 1
peroxisome 0

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CMPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus TAS,IBA 21873635
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm TAS,IBA 21873635
GO:0005829 cytosol TAS --
genes like me logo Genes that share ontologies with CMPK1: view

Pathways & Interactions for CMPK1 Gene

genes like me logo Genes that share pathways with CMPK1: view

Gene Ontology (GO) - Biological Process for CMPK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006139 nucleobase-containing compound metabolic process IEA --
GO:0006163 purine nucleotide metabolic process IBA 21873635
GO:0006165 nucleoside diphosphate phosphorylation IDA 23416111
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process IEA --
GO:0006221 pyrimidine nucleotide biosynthetic process IEA --
genes like me logo Genes that share ontologies with CMPK1: view

No data available for SIGNOR curated interactions for CMPK1 Gene

Drugs & Compounds for CMPK1 Gene

(16) Drugs for CMPK1 Gene - From: DrugBank, PharmGKB, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Gemcitabine Approved Pharma Target, inhibitor Ribonucleotide reductase and DNA synthesis inhibitor, Nucleoside Analogs 2451
Lamivudine Approved, Investigational Pharma Enzyme, substrate Nucleoside analog reverse transcriptase inhibitor 703
Sofosbuvir Approved Pharma Enzyme, substrate 368
Cisplatin Approved Pharma Inhibits DNA synthesis,chemotherapy drug, Potent pro-apoptotic anticancer agent; activates caspase-3, Platinum 3412
Magnesium Approved, Experimental, Investigational Pharma 0

(12) Additional Compounds for CMPK1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • 5'-Adenylphosphoric acid
  • Adenosine 5'-diphosphate
  • ADENOSINE-5'-diphosphATE
  • H3ADP
  • 5'-Adenylphosphate
Agonist, Full agonist, Partial agonist, Gating inhibitor, Antagonist 58-64-0
dcdp
  • 2'-Deoxycytidine 5'-diphosphate
  • 2'-Deoxycytidine diphosphate
  • D-1beta-Ribofuranosylcytosine diphosphate
  • Deoxycytidine diphosphate
  • 2'-Deoxycytidine 5'-diphosphoric acid
800-73-7
genes like me logo Genes that share compounds with CMPK1: view

Transcripts for CMPK1 Gene

mRNA/cDNA for CMPK1 Gene

3 REFSEQ mRNAs :
15 NCBI additional mRNA sequence :
5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CMPK1

Alternative Splicing Database (ASD) splice patterns (SP) for CMPK1 Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6
SP1: -
SP2: - -
SP3:

Relevant External Links for CMPK1 Gene

GeneLoc Exon Structure for
CMPK1

Expression for CMPK1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CMPK1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CMPK1 Gene

This gene is overexpressed in Salivary gland (7.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CMPK1 Gene



Protein tissue co-expression partners for CMPK1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CMPK1

SOURCE GeneReport for Unigene cluster for CMPK1 Gene:

Hs.731647

mRNA Expression by UniProt/SwissProt for CMPK1 Gene:

P30085-KCY_HUMAN
Tissue specificity: Ubiquitously expressed.

Evidence on tissue expression from TISSUES for CMPK1 Gene

  • Nervous system(4.9)
  • Liver(4.6)
  • Intestine(4.6)
  • Muscle(4.5)
  • Lung(3.6)
  • Skin(3.2)
  • Kidney(2.8)
  • Heart(2.7)
  • Blood(2.3)
  • Pancreas(2.2)
  • Spleen(2.2)
  • Lymph node(2.1)
genes like me logo Genes that share expression patterns with CMPK1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for CMPK1 Gene

Orthologs for CMPK1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CMPK1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CMPK1 30 31
  • 99.42 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia CMPK1 30 31
  • 93.71 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CMPK1 30 31
  • 92.4 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Cmpk1 30
  • 90.46 (n)
Mouse
(Mus musculus)
Mammalia Cmpk1 30 17 31
  • 90.31 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CMPK1 31
  • 79 (a)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia CMPK1 31
  • 76 (a)
OneToOne
Chicken
(Gallus gallus)
Aves CMPK1 30
  • 80.78 (n)
CMPK 31
  • 80 (a)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia CMPK1 31
  • 82 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia cmpk1 30
  • 74.75 (n)
African clawed frog
(Xenopus laevis)
Amphibia MGC64474 30
Zebrafish
(Danio rerio)
Actinopterygii cmpk 30 31
  • 66.05 (n)
OneToOne
Dr.24327 30
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP003968 30
  • 57.95 (n)
Fruit Fly
(Drosophila melanogaster)
Insecta Dak1 30 31
  • 56.14 (n)
OneToOne
Worm
(Caenorhabditis elegans)
Secernentea F40F8.1 30 31
  • 57.92 (n)
OneToMany
C29F7.3 31
  • 54 (a)
OneToMany
Baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes URA6 30 31 33
  • 56.05 (n)
OneToMany
K. Lactis Yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0E08053g 30
  • 54.76 (n)
A. gosspyii yeast
(Eremothecium gossypii)
Saccharomycetes AGOS_ACR170C 30
  • 50.84 (n)
Thale Cress
(Arabidopsis thaliana)
eudicotyledons PYR6 30
  • 55.86 (n)
Rice
(Oryza sativa)
Liliopsida Os07g0624700 30
  • 56.54 (n)
Os.10034 30
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 31
  • 62 (a)
OneToOne
Fission Yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes SPCC1795.05c 30
  • 52.85 (n)
Bread mold
(Neurospora crassa)
Ascomycetes NCU02812 30
  • 52.12 (n)
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.4162 30
Species where no ortholog for CMPK1 was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)

Evolution for CMPK1 Gene

ENSEMBL:
Gene Tree for CMPK1 (if available)
TreeFam:
Gene Tree for CMPK1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CMPK1: view image

Paralogs for CMPK1 Gene

Paralogs for CMPK1 Gene

(3) SIMAP similar genes for CMPK1 Gene using alignment to 3 proteins:

  • KCY_HUMAN
  • E9PJD2_HUMAN
  • Q5T0D2_HUMAN

Pseudogenes.org Pseudogenes for CMPK1 Gene

genes like me logo Genes that share paralogs with CMPK1: view

Variants for CMPK1 Gene

Additional dbSNP identifiers (rs#s) for CMPK1 Gene

Variation tolerance for CMPK1 Gene

Residual Variation Intolerance Score: 64.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.72; 66.29% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CMPK1 Gene

Human Gene Mutation Database (HGMD)
CMPK1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CMPK1

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Structural Variations from Database of Genomic Variants (DGV) for CMPK1 Gene

Disorders for CMPK1 Gene

MalaCards: The human disease database

(3) MalaCards diseases for CMPK1 Gene - From: DISEASES

Disorder Aliases PubMed IDs
astrakhan spotted fever
nemaline myopathy 2
  • nem2
siberian tick typhus
  • manchurian typhus
- elite association - COSMIC cancer census association via MalaCards
Search CMPK1 in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with CMPK1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CMPK1 Gene

Publications for CMPK1 Gene

  1. Phosphorylation of deoxycytidine analog monophosphates by UMP-CMP kinase: molecular characterization of the human enzyme. (PMID: 10462544) Van Rompay AR … Karlsson A (Molecular pharmacology 1999) 2 3 4 23
  2. Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium. (PMID: 15550676) Hsu CH … Cheng YC (Molecular pharmacology 2005) 3 23 26
  3. Substrate-induced conformational changes in human UMP/CMP kinase. (PMID: 15163660) Segura-Peña D … Lavie A (The Journal of biological chemistry 2004) 3 4 23
  4. Characterization of human UMP/CMP kinase and its phosphorylation of D- and L-form deoxycytidine analogue monophosphates. (PMID: 11912132) Liou JY … Cheng YC (Cancer research 2002) 3 4 23
  5. Characterization of human UMP-CMP kinase enzymatic activity and 5' untranslated region. (PMID: 11681623) Pearman AT … Stafforini DM (Life sciences 2001) 3 4 23

Products for CMPK1 Gene

Sources for CMPK1 Gene