The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] See more...

Aliases for CLPP Gene

Aliases for CLPP Gene

  • Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit 2 3 5
  • ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial 3 4
  • Endopeptidase Clp 3 4
  • EC 3.4.21.92 4 51
  • ClpP (Caseinolytic Protease, ATP-Dependent, Proteolytic Subunit, E. Coli) Homolog 2
  • ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) 2
  • ClpP Caseinolytic Protease, ATP-Dependent, Proteolytic Subunit Homolog (E. Coli) 2
  • ClpP Caseinolytic Peptidase, ATP-Dependent, Proteolytic Subunit Homolog 3
  • ClpP Caseinolytic Protease, ATP-Dependent, Proteolytic Subunit Homolog 3
  • Putative ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial 3
  • ATP-Dependent Protease ClpAP (E. Coli), Proteolytic Subunit, Human 2
  • ClpP Caseinolytic Peptidase ATP-Dependent, Proteolytic Subunit 3
  • ATP-Dependent Protease ClpAP, Proteolytic Subunit, Human 3
  • DFNB81 3
  • PRLTS3 3
  • CLPP 5

External Ids for CLPP Gene

Previous GeneCards Identifiers for CLPP Gene

  • GC19P006455
  • GC19P006301
  • GC19P006313
  • GC19P006314
  • GC19P006315
  • GC19P006121
  • GC19P006367
  • GC19P006363
  • GC19P006364
  • GC19P006376
  • GC19P006377
  • GC19P006374
  • GC19P006381
  • GC19P006365
  • GC19P006366
  • GC19P006368
  • GC19P006369
  • GC19P006370
  • GC19P006371
  • GC19P006373

Summaries for CLPP Gene

Entrez Gene Summary for CLPP Gene

  • The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008]

GeneCards Summary for CLPP Gene

CLPP (Caseinolytic Mitochondrial Matrix Peptidase Proteolytic Subunit) is a Protein Coding gene. Diseases associated with CLPP include Perrault Syndrome 3 and Perrault Syndrome. Among its related pathways are Neuroscience and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include identical protein binding and peptidase activity.

UniProtKB/Swiss-Prot Summary for CLPP Gene

  • Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PubMed:11923310, PubMed:15522782). Cleaves PINK1 in the mitochondrion (PubMed:22354088).

Gene Wiki entry for CLPP Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for CLPP Gene

Genomics for CLPP Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for CLPP Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around CLPP on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for CLPP

Top Transcription factor binding sites by QIAGEN in the CLPP gene promoter:
  • AML1a
  • Bach1
  • C/EBPalpha
  • Elk-1
  • GATA-1
  • PPAR-alpha
  • SREBP-1a
  • SREBP-1b
  • SREBP-1c
  • YY1

Genomic Locations for CLPP Gene

Genomic Locations for CLPP Gene
chr19:6,361,531-6,370,242
(GRCh38/hg38)
Size:
8,712 bases
Orientation:
Plus strand
chr19:6,361,463-6,368,919
(GRCh37/hg19)
Size:
7,457 bases
Orientation:
Plus strand

Genomic View for CLPP Gene

Genes around CLPP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLPP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLPP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLPP Gene

Proteins for CLPP Gene

  • Protein details for CLPP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q16740-CLPP_HUMAN
    Recommended name:
    ATP-dependent Clp protease proteolytic subunit, mitochondrial
    Protein Accession:
    Q16740
    Secondary Accessions:
    • B2R4W5

    Protein attributes for CLPP Gene

    Size:
    277 amino acids
    Molecular mass:
    30180 Da
    Quaternary structure:
    • Fourteen CLPP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity. Component of the Clp complex formed by the assembly of two CLPP heptameric rings with two CLPX hexameric rings, giving rise to a symmetrical structure with two central CLPP rings flanked by a CLPX ring at either end of the complex.

    Three dimensional structures from OCA and Proteopedia for CLPP Gene

neXtProt entry for CLPP Gene

Selected DME Specific Peptides for CLPP Gene

Q16740:
  • RDRYMSP
  • RGERAYD
  • AIYDTMQ
  • VTAGLAI
  • RIMIHQP
  • DIYSRLLR
  • GLAIYDTM
  • SMGSLLL
  • YINSPGG
  • GQAASMGS
  • LPNSRIMIHQ
  • PIVVEQT
  • TAGLAIYDT
  • IYDTMQY
  • CVGQAAS

Post-translational modifications for CLPP Gene

  • Ubiquitination at Lys203
  • Modification sites at PhosphoSitePlus

Other Protein References for CLPP Gene

Domains & Families for CLPP Gene

Gene Families for CLPP Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Enzymes
  • Potential drug targets
  • Predicted intracellular proteins

Protein Domains for CLPP Gene

InterPro:
Blocks:
  • Clp protease
ProtoNet:

Suggested Antigen Peptide Sequences for CLPP Gene

GenScript: Design optimal peptide antigens:
  • Endopeptidase Clp (CLPP_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q16740

UniProtKB/Swiss-Prot:

CLPP_HUMAN :
  • Belongs to the peptidase S14 family.
Family:
  • Belongs to the peptidase S14 family.
genes like me logo Genes that share domains with CLPP: view

Function for CLPP Gene

Molecular function for CLPP Gene

UniProtKB/Swiss-Prot Function:
Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PubMed:11923310, PubMed:15522782). Cleaves PINK1 in the mitochondrion (PubMed:22354088).
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=Hydrolysis of proteins to small peptides in the presence of ATP and magnesium. Alpha-casein is the usual test substrate. In the absence of ATP, only oligopeptides shorter than five residues are hydrolyzed (such as succinyl-Leu-Tyr-|-NHMec, and Leu-Tyr-Leu-|-Tyr-Trp, in which cleavage of the -Tyr-|-Leu- and -Tyr-|-Trp bonds also occurs).; EC=3.4.21.92; Evidence={ECO:0000269|PubMed:11923310, ECO:0000269|PubMed:15522782, ECO:0000269|PubMed:22354088};.
GENATLAS Biochemistry:
ATP dependent protease involved in degradation of incorreclly folded or unfolded proteins,catalytic subunit,ClpP E coli homolog,highly expressed in skeletal muscle,heart,liver,pancreas,located in the mitochondrial matrix

Enzyme Numbers (IUBMB) for CLPP Gene

Gene Ontology (GO) - Molecular Function for CLPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004175 endopeptidase activity IDA 22354088
GO:0004176 ATP-dependent peptidase activity IBA 21873635
GO:0004252 serine-type endopeptidase activity IEA,IDA 11923310
GO:0005515 protein binding IPI 11923310
GO:0008233 peptidase activity IEA,TAS 8543061
genes like me logo Genes that share ontologies with CLPP: view
genes like me logo Genes that share phenotypes with CLPP: view

Human Phenotype Ontology for CLPP Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for CLPP Gene

MGI Knock Outs for CLPP:
  • Clpp Clpp<tm1a(EUCOMM)Wtsi>

Animal Model Products

  • Taconic Biosciences Mouse Models for CLPP

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLPP

No data available for Phenotypes From GWAS Catalog , Transcription Factor Targets and HOMER Transcription for CLPP Gene

Localization for CLPP Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLPP Gene

Mitochondrion matrix.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CLPP gene
Compartment Confidence
mitochondrion 5
plasma membrane 2
extracellular 2
nucleus 2
endoplasmic reticulum 2
cytosol 2
cytoskeleton 1
peroxisome 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for CLPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA 22354088
GO:0005759 mitochondrial matrix IEA,IDA 10525407
GO:0009368 endopeptidase Clp complex IBA,IDA 11923310
genes like me logo Genes that share ontologies with CLPP: view

Pathways & Interactions for CLPP Gene

PathCards logo

SuperPathways for CLPP Gene

genes like me logo Genes that share pathways with CLPP: view

Pathways by source for CLPP Gene

2 Cell Signaling Technology pathways for CLPP Gene

Gene Ontology (GO) - Biological Process for CLPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006508 proteolysis IEA --
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins IBA 21873635
GO:0033619 membrane protein proteolysis IDA 22354088
GO:0051603 proteolysis involved in cellular protein catabolic process IDA 11923310
genes like me logo Genes that share ontologies with CLPP: view

No data available for SIGNOR curated interactions for CLPP Gene

Drugs & Compounds for CLPP Gene

(4) Drugs for CLPP Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Magnesium Approved, Experimental, Investigational Pharma 0
N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE Experimental Pharma Target 0
N-Formylmethionine Experimental Pharma Target 0
genes like me logo Genes that share compounds with CLPP: view

Transcripts for CLPP Gene

mRNA/cDNA for CLPP Gene

1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLPP

Alternative Splicing Database (ASD) splice patterns (SP) for CLPP Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b
SP1: - - -
SP2: -
SP3: - -
SP4:
SP5: -

Relevant External Links for CLPP Gene

GeneLoc Exon Structure for
CLPP

Expression for CLPP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for CLPP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CLPP Gene

This gene is overexpressed in Nasal epithelium (11.0) and Peripheral blood mononuclear cells (7.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for CLPP Gene



Protein tissue co-expression partners for CLPP Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for CLPP

SOURCE GeneReport for Unigene cluster for CLPP Gene:

Hs.515092

mRNA Expression by UniProt/SwissProt for CLPP Gene:

Q16740-CLPP_HUMAN
Tissue specificity: Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney.

Evidence on tissue expression from TISSUES for CLPP Gene

  • Muscle(4.7)
  • Liver(4.6)
  • Lung(3.3)
  • Heart(3)
  • Skin(2.9)
  • Nervous system(2.8)
  • Intestine(2.7)
  • Kidney(2.6)
  • Stomach(2.6)
  • Blood(2.4)
  • Spleen(2.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for CLPP Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • digestive
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • head
  • inner ear
  • jaw
  • mandible
  • maxilla
  • middle ear
  • mouth
  • neck
  • outer ear
  • pituitary gland
  • skull
Thorax:
  • breast
  • chest wall
  • clavicle
  • lung
  • rib
  • rib cage
  • scapula
  • sternum
Pelvis:
  • ovary
  • pelvis
  • penis
  • prostate
  • testicle
  • uterus
  • vagina
  • vulva
Limb:
  • ankle
  • arm
  • digit
  • elbow
  • femur
  • fibula
  • finger
  • foot
  • forearm
  • hand
  • hip
  • humerus
  • knee
  • lower limb
  • radius
  • shin
  • shoulder
  • thigh
  • tibia
  • toe
  • ulna
  • upper limb
  • wrist
General:
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal column
  • vertebrae
genes like me logo Genes that share expression patterns with CLPP: view

No data available for mRNA differential expression in normal tissues for CLPP Gene

Orthologs for CLPP Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for CLPP Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia CLPP 30 31
  • 98.92 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia CLPP 31
  • 92 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia CLPP 30 31
  • 90.2 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia CLPP 30 31
  • 89.67 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Clpp 30 17 31
  • 83.66 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Clpp 30
  • 81.45 (n)
Lizard
(Anolis carolinensis)
Reptilia CLPP 31
  • 77 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia clpp 30
  • 73.48 (n)
Str.5533 30
African clawed frog
(Xenopus laevis)
Amphibia Xl.11723 30
Zebrafish
(Danio rerio)
Actinopterygii clpp 30 31
  • 72.83 (n)
OneToOne
wufj37a05 30
Fruit Fly
(Drosophila melanogaster)
Insecta CG5045 30 31 32
  • 68.16 (n)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009019 30
  • 67.61 (n)
Worm
(Caenorhabditis elegans)
Secernentea ZK970.2 32
  • 65 (a)
clpp-1 30 31
  • 55.19 (n)
OneToOne
Thale Cress
(Arabidopsis thaliana)
eudicotyledons NCLPP7 30
  • 58 (n)
Rice
(Oryza sativa)
Liliopsida Os02g0634500 30
  • 68.01 (n)
Os.4948 30
Wheat
(Triticum aestivum)
Liliopsida Ta.9277 30
Corn
(Zea mays)
Liliopsida Zm.16493 30
Sea Squirt
(Ciona savignyi)
Ascidiacea CSA.3464 31
  • 61 (a)
OneToOne
Sea Vase
(Ciona intestinalis)
Ascidiacea Cin.4342 30
Species where no ortholog for CLPP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Oppossum (Monodelphis domestica)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)

Evolution for CLPP Gene

ENSEMBL:
Gene Tree for CLPP (if available)
TreeFam:
Gene Tree for CLPP (if available)
Aminode:
Evolutionary constrained regions (ECRs) for CLPP: view image

Paralogs for CLPP Gene

No data available for Paralogs for CLPP Gene

Variants for CLPP Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for CLPP Gene

SNP ID Clinical significance and condition Chr 19 pos Variation AA Info Type
668246 Likely Benign: not provided 6,366,249(+) G/A INTRON_VARIANT
717397 Likely Benign: not provided 6,368,542(+) C/T SYNONYMOUS_VARIANT
721645 Likely Benign: not provided 6,362,438(+) A/T INTRON_VARIANT
723455 Likely Benign: not provided 6,364,453(+) T/C SYNONYMOUS_VARIANT
747360 Likely Benign: not provided 6,361,895(+) C/T SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for CLPP Gene

Variation tolerance for CLPP Gene

Residual Variation Intolerance Score: 29.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.14; 3.06% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CLPP Gene

Human Gene Mutation Database (HGMD)
CLPP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
CLPP

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CLPP Gene

Disorders for CLPP Gene

MalaCards: The human disease database

(13) MalaCards diseases for CLPP Gene - From: UniProtKB/Swiss-Prot, OMIM, ClinVar, GTR, Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
perrault syndrome 3
  • prlts3
perrault syndrome
  • gonadal dysgenesis, xx type
codas syndrome
  • cerebral, ocular, dental, auricular, and skeletal anomalies syndrome
myasthenic syndrome, congenital, 12
  • cms12
learning disability
  • academic skill disorder
- elite association - COSMIC cancer census association via MalaCards
Search CLPP in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CLPP_HUMAN
  • Perrault syndrome 3 (PRLTS3) [MIM:614129]: A sex-influenced disorder characterized by sensorineural deafness in both males and females, and ovarian dysgenesis in females. Affected females have primary amenorrhea, streak gonads, and infertility, whereas affected males show normal pubertal development and are fertile. A spectrum of additional clinical features, including cerebellar ataxia, learning disability, and peripheral neuropathy, have been described in some PRLTS3 affected individuals. {ECO:0000269 PubMed:23541340, ECO:0000269 PubMed:25956234}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for CLPP

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with CLPP: view

No data available for Genatlas for CLPP Gene

Publications for CLPP Gene

  1. Human ClpP protease: cDNA sequence, tissue-specific expression and chromosomal assignment of the gene. (PMID: 8543061) Bross P … Gregersen N (FEBS letters 1995) 2 3 4 23
  2. Exome analysis identified a novel missense mutation in the CLPP gene in a consanguineous Saudi family expanding the clinical spectrum of Perrault Syndrome type-3. (PMID: 25956234) Ahmed S … Al-Aama JY (Journal of the neurological sciences 2015) 3 4
  3. Perrault syndrome is caused by recessive mutations in CLPP, encoding a mitochondrial ATP-dependent chambered protease. (PMID: 23541340) Jenkinson EM … Newman WG (American journal of human genetics 2013) 3 4
  4. Human CLPP reverts the longevity phenotype of a fungal ClpP deletion strain. (PMID: 23360988) Fischer F … Osiewacz HD (Nature communications 2013) 2 3
  5. Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment. (PMID: 22354088) Greene AW … Fon EA (EMBO reports 2012) 3 4

Products for CLPP Gene

  • Signalway ELISA kits for CLPP
  • Signalway Proteins for CLPP

Sources for CLPP Gene