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CLMN (Calmin) is a Protein Coding gene. Diseases associated with CLMN include Smith-Mccort Dysplasia 1 and Psoriasis 2. Gene Ontology (GO) annotations related to this gene include actin binding. An important paralog of this gene is SYNE1.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003779 | actin binding | IEA | -- |
GO:0005515 | protein binding | IEA | -- |
GO:0051015 | actin filament binding | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005640 | nuclear outer membrane | IBA | 21873635 |
GO:0005737 | cytoplasm | IEA,IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
GO:0034993 | meiotic nuclear membrane microtubule tethering complex | IBA | 21873635 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0007097 | nuclear migration | IBA | 21873635 |
GO:0008285 | negative regulation of cell proliferation | IEA,IBA | 21873635 |
GO:0031175 | neuron projection development | IEA | -- |
ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15a | · | 15b | · | 15c | ^ | 16 | ^ | 17a | · | 17b |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | |||||||||||||||||||||||||||||||||||||||||||
SP2: | - | ||||||||||||||||||||||||||||||||||||||||||||
SP3: | - | ||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||
SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||
SP7: |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | CLMN 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | CLMN 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | CLMN 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Clmn 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Clmn 30 |
|
||
Oppossum (Monodelphis domestica) |
Mammalia | CLMN 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | CLMN 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | CLMN 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | CLMN 31 |
|
OneToOne | |
Zebrafish (Danio rerio) |
Actinopterygii | CLMN 31 |
|
OneToOne | |
Fruit Fly (Drosophila melanogaster) |
Insecta | kst 31 |
|
OneToOne | |
Worm (Caenorhabditis elegans) |
Secernentea | M116.5 31 |
|
OneToOne |
SNP ID | Clinical significance and condition | Chr 14 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs10131338 | Benign: not provided | 95,203,795(-) |
G/A NM_024734.4(CLMN):c.1554C>T (p.His518=) |
SYNONYMOUS | |
rs10149705 | Benign: not provided. - | 95,191,685(-) |
G/Ap.Pro963Leu NM_024734.4(CLMN):c.2888C>T (p.Pro963Leu) |
MISSENSE | |
rs114143013 | Benign: not provided | 95,203,150(-) |
C/T NM_024734.4(CLMN):c.2199G>A (p.Glu733=) |
SYNONYMOUS | |
rs116654567 | Benign: not provided | 95,203,884(-) |
C/A NM_024734.4(CLMN):c.1465G>T (p.Val489Phe) |
MISSENSE | |
rs118150470 | Likely Benign: not provided | 95,209,454(-) |
C/T NM_024734.4(CLMN):c.826G>A (p.Glu276Lys) |
MISSENSE |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1325e59 | CNV | duplication | 20981092 |
dgv384n67 | CNV | gain | 20364138 |
dgv675e212 | CNV | loss | 25503493 |
dgv89e55 | CNV | gain | 17911159 |
esv2250778 | CNV | deletion | 18987734 |
esv2749047 | CNV | deletion | 23290073 |
esv3306150 | CNV | mobile element insertion | 20981092 |
esv3395087 | CNV | insertion | 20981092 |
esv3551998 | CNV | deletion | 23714750 |
esv3635396 | CNV | gain | 21293372 |
esv3635399 | CNV | loss | 21293372 |
nsv1036738 | CNV | gain | 25217958 |
nsv1070233 | CNV | deletion | 25765185 |
nsv1070652 | CNV | deletion | 25765185 |
nsv1131160 | CNV | deletion | 24896259 |
nsv1143756 | CNV | deletion | 24896259 |
nsv1412 | CNV | insertion | 18451855 |
nsv472215 | CNV | novel sequence insertion | 20440878 |
nsv476271 | CNV | novel sequence insertion | 20440878 |
nsv528121 | CNV | loss | 19592680 |
nsv565630 | CNV | loss | 21841781 |
Disorder | Aliases | PubMed IDs |
---|---|---|
smith-mccort dysplasia 1 |
|
|
psoriasis 2 |
|
|
fraser syndrome 1 |
|
|
psoriasis 3 |
|
|
dyggve-melchior-clausen disease |
|
|