Aliases for CLIC6 Gene
External Ids for CLIC6 Gene
Previous HGNC Symbols for CLIC6 Gene
Previous GeneCards Identifiers for CLIC6 Gene
This gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2015]
GeneCards Summary for CLIC6 Gene
CLIC6 (Chloride Intracellular Channel 6) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Hepatic ABC Transporters. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and chloride channel activity. An important paralog of this gene is CLIC5.
UniProtKB/Swiss-Prot Summary for CLIC6 Gene
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity).