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Aliases for CLEC19A Gene

Aliases for CLEC19A Gene

  • C-Type Lectin Domain Containing 19A 2 3 5
  • C-Type Lectin Domain Family 19, Member A 2
  • C-Type Lectin Domain Family 19 Member A 2

External Ids for CLEC19A Gene

Previous GeneCards Identifiers for CLEC19A Gene

  • GC00U926688

Summaries for CLEC19A Gene

GeneCards Summary for CLEC19A Gene

CLEC19A (C-Type Lectin Domain Containing 19A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include carbohydrate binding.

Additional gene information for CLEC19A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLEC19A Gene

Genomics for CLEC19A Gene

GeneHancer (GH) Regulatory Elements for CLEC19A Gene

Promoters and enhancers for CLEC19A Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16I019284 Enhancer 0.5 ENCODE 550.8 -1.3 -1261 0.4 ZNF664 JUND HNF4A FOSL2 ZIC2 CLEC19A SYT17
GH16I019289 Enhancer 0.5 ENCODE 0.8 +4.4 4380 0.9 ZFHX2 USF1 ZMYM3 ZNF398 EGR2 CLEC19A ENSG00000259871
GH16I019294 Enhancer 1 Ensembl ENCODE 0.4 +8.9 8901 1.3 MAX EBF1 BMI1 CEBPG BATF KLF5 IRF4 RELA ZFHX2 ZBTB48 CLEC19A ENSG00000259871
GH16I019209 Enhancer 1.3 FANTOM5 Ensembl ENCODE 0.2 -74.2 -74247 3.2 HDGF CTCF BMI1 BATF RAD21 KLF5 IRF4 RELA POLR2A ZNF207 SYT17 COQ7 RNU4-46P SMG1 CLEC19A
GH16I019291 Enhancer 0.6 ENCODE 0.4 +5.8 5847 0.9 RFX1 MAX BACH1 MAFG SIN3A BMI1 ZNF121 RFX3 NFE2 MAFK ENSG00000259925 CLEC19A ENSG00000259871
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around CLEC19A on UCSC Golden Path with GeneCards custom track

Genomic Locations for CLEC19A Gene

Genomic Locations for CLEC19A Gene
chr16:19,285,739-19,324,537
(GRCh38/hg38)
Size:
38,799 bases
Orientation:
Plus strand
chr16:19,297,061-19,333,467
(GRCh37/hg19)

Genomic View for CLEC19A Gene

Genes around CLEC19A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLEC19A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLEC19A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLEC19A Gene

Proteins for CLEC19A Gene

  • Protein details for CLEC19A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6UXS0-CL19A_HUMAN
    Recommended name:
    C-type lectin domain family 19 member A
    Protein Accession:
    Q6UXS0
    Secondary Accessions:
    • Q0VF32

    Protein attributes for CLEC19A Gene

    Size:
    136 amino acids
    Molecular mass:
    15448 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CLEC19A Gene

Post-translational modifications for CLEC19A Gene

Other Protein References for CLEC19A Gene

No data available for DME Specific Peptides for CLEC19A Gene

Domains & Families for CLEC19A Gene

Gene Families for CLEC19A Gene

Protein Domains for CLEC19A Gene

Suggested Antigen Peptide Sequences for CLEC19A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CLEC19A: view

No data available for UniProtKB/Swiss-Prot for CLEC19A Gene

Function for CLEC19A Gene

Phenotypes From GWAS Catalog for CLEC19A Gene

Gene Ontology (GO) - Molecular Function for CLEC19A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with CLEC19A: view

Phenotypes for CLEC19A Gene

GenomeRNAi human phenotypes for CLEC19A:
genes like me logo Genes that share phenotypes with CLEC19A: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CLEC19A Gene

Localization for CLEC19A Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLEC19A Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CLEC19A gene
Compartment Confidence
extracellular 3

Gene Ontology (GO) - Cellular Components for CLEC19A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with CLEC19A: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for CLEC19A Gene

Pathways & Interactions for CLEC19A Gene

SuperPathways for CLEC19A Gene

No Data Available

Interacting Proteins for CLEC19A Gene

Gene Ontology (GO) - Biological Process for CLEC19A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CLEC19A Gene

Drugs & Compounds for CLEC19A Gene

No Compound Related Data Available

Transcripts for CLEC19A Gene

mRNA/cDNA for CLEC19A Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLEC19A Gene

C-type lectin domain family 19, member A:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CLEC19A Gene

No ASD Table

Relevant External Links for CLEC19A Gene

GeneLoc Exon Structure for
CLEC19A
ECgene alternative splicing isoforms for
CLEC19A

Expression for CLEC19A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CLEC19A Gene

Protein differential expression in normal tissues from HIPED for CLEC19A Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CLEC19A Gene



Protein tissue co-expression partners for CLEC19A Gene

NURSA nuclear receptor signaling pathways regulating expression of CLEC19A Gene:

CLEC19A

SOURCE GeneReport for Unigene cluster for CLEC19A Gene:

Hs.632180
genes like me logo Genes that share expression patterns with CLEC19A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CLEC19A Gene

Orthologs for CLEC19A Gene

This gene was present in the common ancestor of animals.

Orthologs for CLEC19A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CLEC19A 33
  • 98.75 (n)
dog
(Canis familiaris)
Mammalia CLEC19A 33
  • 88.71 (n)
cow
(Bos Taurus)
Mammalia CLEC19A 33 34
  • 88.35 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CLEC19A 34
  • 75 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CLEC19A 34
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves LOC771758 33
  • 76.97 (n)
CLEC19A 34
  • 58 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CLEC19A 34
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia clec19a 33
  • 67.77 (n)
zebrafish
(Danio rerio)
Actinopterygii clec19a 33 34
  • 67.58 (n)
worm
(Caenorhabditis elegans)
Secernentea clec-149 34
  • 9 (a)
OneToMany
Species where no ortholog for CLEC19A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CLEC19A Gene

ENSEMBL:
Gene Tree for CLEC19A (if available)
TreeFam:
Gene Tree for CLEC19A (if available)

Paralogs for CLEC19A Gene

(1) SIMAP similar genes for CLEC19A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CLEC19A: view

No data available for Paralogs for CLEC19A Gene

Variants for CLEC19A Gene

Sequence variations from dbSNP and Humsavar for CLEC19A Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000099485 -- 19,293,981(+) T/C intron_variant
rs1000146555 -- 19,284,309(+) C/T upstream_transcript_variant
rs1000253642 -- 19,290,478(+) C/T intron_variant
rs1000316230 -- 19,311,110(+) T/C downstream_transcript_variant
rs1000517488 -- 19,289,507(+) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for CLEC19A Gene

Variant ID Type Subtype PubMed ID
nsv833162 CNV loss 17160897
nsv571582 CNV gain 21841781
nsv436835 CNV insertion 17901297
nsv1160368 CNV deletion 26073780

Variation tolerance for CLEC19A Gene

Gene Damage Index Score: 7.55; 82.41% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for CLEC19A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CLEC19A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLEC19A Gene

Disorders for CLEC19A Gene

Additional Disease Information for CLEC19A

No disorders were found for CLEC19A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CLEC19A Gene

Publications for CLEC19A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark HF … Gray A (Genome research 2003) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for CLEC19A Gene

Sources for CLEC19A Gene

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