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CLEC18C (C-Type Lectin Domain Family 18 Member C) is a Protein Coding gene. Diseases associated with CLEC18C include Cellular Myxoid Liposarcoma and Pleomorphic Liposarcoma. Among its related pathways are Guidance Cues and Growth Cone Motility and Activation of cAMP-Dependent PKA. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC18A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0030246 | carbohydrate binding | IEA | -- |
GO:0030247 | polysaccharide binding | IDA | 26170455 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005576 | extracellular region | IEA | -- |
GO:0005615 | extracellular space | IBA | 21873635 |
GO:0005768 | endosome | TAS | 26170455 |
GO:0005783 | endoplasmic reticulum | TAS | 26170455 |
GO:0005794 | Golgi apparatus | TAS | 26170455 |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Activation of cAMP-Dependent PKA |
Activation of cAMP-Dependent PKA
.77
cAMP Pathway
.77
|
Activation of PKA through GPCR
.71
PKA Signaling
.56
|
2 | PAK Pathway |
Antioxidant Action of Vitamin-C
.56
PAK Pathway
.56
|
Epithelial Adherens Junctions
.36
|
3 | Actin Nucleation by ARP-WASP Complex |
Actin Nucleation by ARP-WASP Complex
.66
|
RhoA Pathway
.35
|
4 | RhoGDI Pathway |
Fc-GammaR-Mediated Phagocytosis in Macrophages
.33
|
RhoGDI Pathway
.33
|
5 | Sweet Taste Signaling |
Cellular Effects of Sildenafil
.46
|
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | -- 31 |
|
OneToMany | |
Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
OneToMany | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
Dog (Canis familiaris) |
Mammalia | -- 31 |
|
OneToMany | |
Mouse (Mus musculus) |
Mammalia | Clec18a 31 |
|
OneToMany | |
Cow (Bos Taurus) |
Mammalia | MRCL 31 |
|
OneToMany | |
Chicken (Gallus gallus) |
Aves | -- 31 |
|
OneToMany | |
Worm (Caenorhabditis elegans) |
Secernentea | lon-1 31 |
|
OneToMany |
Disorder | Aliases | PubMed IDs |
---|---|---|
cellular myxoid liposarcoma |
|
|
pleomorphic liposarcoma |
|
|
myxoid liposarcoma |
|
|
well-differentiated liposarcoma |
|
|
synovium cancer |
|
|