Aliases for CLEC18A Gene
External Ids for CLEC18A Gene
Previous HGNC Symbols for CLEC18A Gene
Previous GeneCards Identifiers for CLEC18A Gene
This is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C-type lectin domains. These domains bind to carbohydrates in the presence of calcium, and may be involved in cell adhesion, immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2012]
GeneCards Summary for CLEC18A Gene
CLEC18A (C-Type Lectin Domain Family 18 Member A) is a Protein Coding gene. Diseases associated with CLEC18A include Cellular Myxoid Liposarcoma. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC18B.
UniProtKB/Swiss-Prot Summary for CLEC18A Gene
Binds polysaccharides in a Ca(2+)-independent manner with a preferentially binding to fucoidan, beta-glucans and galactans (PubMed:26170455).