Aliases for CLEC14A Gene
External Ids for CLEC14A Gene
Previous HGNC Symbols for CLEC14A Gene
Previous GeneCards Identifiers for CLEC14A Gene
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting. [provided by RefSeq, Jan 2012]
GeneCards Summary for CLEC14A Gene
CLEC14A (C-Type Lectin Domain Containing 14A) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and Phospholipase-C Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD93.