Aliases for CLEC11A Gene
External Ids for CLEC11A Gene
Previous HGNC Symbols for CLEC11A Gene
Previous GeneCards Identifiers for CLEC11A Gene
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLEC11A Gene
CLEC11A (C-Type Lectin Domain Containing 11A) is a Protein Coding gene. Diseases associated with CLEC11A include Chronic Granulomatous Disease and Cutaneous Solitary Mastocytoma. Among its related pathways are ERK Signaling and TGF-Beta Pathway. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and growth factor activity. An important paralog of this gene is CLEC3A.
UniProtKB/Swiss-Prot Summary for CLEC11A Gene
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999). Important for repair and maintenance of adult bone (By similarity).