Aliases for CLEC11A Gene
External Ids for CLEC11A Gene
Previous HGNC Symbols for CLEC11A Gene
Previous GeneCards Identifiers for CLEC11A Gene
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLEC11A Gene
CLEC11A (C-Type Lectin Domain Containing 11A) is a Protein Coding gene. Diseases associated with CLEC11A include Chronic Granulomatous Disease. Among its related pathways are Nanog in Mammalian ESC Pluripotency and Apoptotic Pathways in Synovial Fibroblasts. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and growth factor activity. An important paralog of this gene is CLEC3B.
UniProtKB/Swiss-Prot Summary for CLEC11A Gene
Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts (PubMed:27976999). Important for repair and maintenance of adult bone (By similarity).