Aliases for CLDN5 Gene
Aliases for CLDN5 Gene
External Ids for CLDN5 Gene
- HGNC: 2047
- Entrez Gene: 7122
- Ensembl: ENSG00000184113
- OMIM: 602101
- UniProtKB: O00501
Previous HGNC Symbols for CLDN5 Gene
- AWAL
- TMVCF
Previous GeneCards Identifiers for CLDN5 Gene
- GC22M016450
- GC22M017885
- GC22M003131
Summaries for CLDN5 Gene
-
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2018]
GeneCards Summary for CLDN5 Gene
CLDN5 (Claudin 5) is a Protein Coding gene. Diseases associated with CLDN5 include Velocardiofacial Syndrome and Gray Platelet Syndrome. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include identical protein binding and structural molecule activity. An important paralog of this gene is CLDN3.
UniProtKB/Swiss-Prot for CLDN5 Gene
-
Plays a major role in tight junction-specific obliteration of the intercellular space.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLDN5 Gene
Genomics for CLDN5 Gene
GeneHancer (GH) Regulatory Elements for CLDN5 Gene
Promoters and enhancers for CLDN5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around CLDN5 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the CLDN5 gene promoter:
-
- c-Myb
- PPAR-alpha
- TBP
- Spz1
- ATF-2
- CRE-BP1
- Zic3
- MyoD
- GATA-1
- AP-2alpha
Regulatory Element Products
Genomic Locations for CLDN5 Gene
Genomic Locations for CLDN5 Gene
- chr22:19,523,024-19,527,545
- (GRCh38/hg38)
- Size:
- 4,522 bases
- Orientation:
- Minus strand
- chr22:19,510,547-19,515,068
- (GRCh37/hg19)
- Size:
- 4,522 bases
- Orientation:
- Minus strand
Genomic View for CLDN5 Gene
Genes around CLDN5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q11.21 by Entrez Gene
- 22q11.21 by HGNC
- 22q11.21 by Ensembl
CLDN5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CLDN5 Gene
Proteins for CLDN5 Gene
-
Protein details for CLDN5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O00501-CLD5_HUMAN
- Recommended name:
- Claudin-5
- Protein Accession:
- O00501
- B3KS11
- Q53XW2
- Q8WUW3
Protein attributes for CLDN5 Gene
- Size:
- 218 amino acids
- Molecular mass:
- 23147 Da
- Quaternary structure:
-
- Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with MPDZ (By similarity).
Protein Expression for CLDN5 Gene
Post-translational modifications for CLDN5 Gene
Other Protein References for CLDN5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for CLDN5
- Novus Biologicals Antibodies for CLDN5
-
Abcam antibodies for CLDN5
- Invitrogen Antibodies for CLDN5
- antibodies-online: Search results for 91 available CLDN5 Antibodies ranked by validation data
- Compare Top CLDN5 Antibodies
-
Recommended
- 38 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 9 IHC (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 IHC Antibodies (anti-mouse)
- 3 IHC (p) Antibodies (anti-mouse)
- 28 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 3 IHC Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- GeneTex CLDN5 Antibody for CLDN5
-
Santa Cruz Biotechnology (SCBT) Antibodies for CLDN5
Protein Products
-
OriGene Purified Proteins for CLDN5
- Search Origene for MassSpec and Protein Over-expression Lysates for CLDN5
- Origene Custom Protein Services for CLDN5
- Search GeneTex for Proteins for CLDN5
-
Abcam proteins for CLDN5
Assay Products
No data available for DME Specific Peptides for CLDN5 Gene
Domains & Families for CLDN5 Gene
Gene Families for CLDN5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted membrane proteins
- Transporters
Protein Domains for CLDN5 Gene
- Blocks:
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CLDN5 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O00501- Family:
-
- Belongs to the claudin family.
Function for CLDN5 Gene
Molecular function for CLDN5 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a major role in tight junction-specific obliteration of the intercellular space.
- GENATLAS Biochemistry:
- claudin 5,clostridium perfringens enterotoxin receptor-like,transmembrane protein,integral membrane protein,claudin family of major structural components of tight junction (TJ) strands,expressed in lung,heart,skeletal muscle,homolog to rat ventral prostate protein,deleted in velocardiofacial syndrome,DiGeorge region
Phenotypes From GWAS Catalog for CLDN5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005198 | structural molecule activity | IEA | -- |
| GO:0042802 | identical protein binding | ISS | -- |
Phenotypes for CLDN5 Gene
- MGI mutant phenotypes for CLDN5:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CLDN5:
Animal Models for CLDN5 Gene
- MGI Knock Outs for CLDN5:
-
- Cldn5 Cldn5<tm1Sts>
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for CLDN5
-
CRISPR Products
-
OriGene CRISPR knockouts for CLDN5
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- Applied Biological Materials CRISPR for CLDN5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CLDN5
- GenScript: Design CRISPR guide RNA sequences for CLDN5
miRNA for CLDN5 Gene
- miRTarBase miRNAs that target CLDN5
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for CLDN5
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- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLDN5
- genomics-online: shRNA clones - Search results for available CLDN5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CLDN5
- VectorBuilder custom plasmid, inducible vectors for CLDN5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CLDN5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CLDN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN5
- genomics-online: cdna clones - Search results for available CLDN5 gene related products
- orf clones - Search results for available CLDN5 gene related products
- Applied Biological Materials Clones for CLDN5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CLDN5 (Claudin-5)
Cell Line Products
-
Horizon Cell Lines for CLDN5
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CLDN5 Gene
Localization for CLDN5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CLDN5 Gene
- Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytoskeleton | 2 |
| nucleus | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | IDA,IEA | 25978380 |
| GO:0005911 | cell-cell junction | IDA | 18065521 |
| GO:0005923 | bicellular tight junction | IEA,ISS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | TAS,IEA | 9192844 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for CLDN5 Gene
Pathways & Interactions for CLDN5 Gene
Pathways by source for CLDN5 Gene
1 BioSystems pathway for CLDN5 Gene
4 Reactome pathways for CLDN5 Gene
4 KEGG pathways for CLDN5 Gene
2 GeneGo (Thomson Reuters) pathways for CLDN5 Gene
6 R&D Systems pathways for CLDN5 Gene
- Blood-Brain Barrier and Immune Cell Transmigration: CCL2/MCP-1 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: ICAM-1/CD54 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview
- Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways
- Blood-Brain Barrier and Immune Cell Transmigration: VEGF Signaling Pathways
3 Qiagen pathways for CLDN5 Gene
Interacting Proteins for CLDN5 Gene
GPS-Prot Interaction Network for CLDN5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003151 | outflow tract morphogenesis | TAS | 9192844 |
| GO:0007043 | cell-cell junction assembly | IMP | 23288152 |
| GO:0007179 | transforming growth factor beta receptor signaling pathway | IDA | 21168935 |
| GO:0007612 | learning | TAS | 9192844 |
| GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules | ISS | -- |
No data available for SIGNOR curated interactions for CLDN5 Gene
Transcripts for CLDN5 Gene
mRNA/cDNA for CLDN5 Gene
- (6) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (249) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000406028 2548 bps (uc062bmo.1)
- ENST00000618236 1374 bps (uc062bmp.1)
- ENST00000403084 2357 bps (uc010grr.3)
- ENST00000413119 1760 bps (uc002zpu.3)
CRISPR Products
-
OriGene CRISPR knockouts for CLDN5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CLDN5
- genomics-online: gRNA clones - Search results for available CLDN5 gene related products
- Applied Biological Materials CRISPR for CLDN5
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for CLDN5
- GenScript: Design CRISPR guide RNA sequences for CLDN5
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for CLDN5
- Browse OriGene Inhibitory RNA Products For CLDN5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLDN5
- genomics-online: shRNA clones - Search results for available CLDN5 gene related products
Clone Products
- Sino Biological Human cDNA Clone for CLDN5
- VectorBuilder custom plasmid, inducible vectors for CLDN5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CLDN5
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CLDN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN5
- genomics-online: cdna clones - Search results for available CLDN5 gene related products
- orf clones - Search results for available CLDN5 gene related products
- Applied Biological Materials Clones for CLDN5
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
- R&D Systems cDNA Clones for CLDN5 (Claudin-5)
Expression for CLDN5 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Primitive Heart Tube Cells Primitive Heart Tube
- Atrioventricular Canal Cells Atrioventricular Canal
- Heart Tube
- Brain (Nervous System)
-
Endothelium (Cardiovascular System)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
- Endothelial cells(Lippmann ES et. al. 2012)
- Brain microvascular endothelial cells(Lippmann ES et. al. 2012)
- Kidney (Urinary System)
- Adipose (Muscoskeletal System)
- Gonad
- NULL (Uncategorized)
-
Head Mesenchyme (Muscoskeletal System)
- Dental Mesenchymal Cells Branchial Arch 1
-
Tooth
- Dental Mesenchymal Cells Branchial Arch 1
-
Epithelial Cells
- Mature Choroid Plexus Cells Choroid Plexus
-
Extraembryonic Mesoderm (Extraembryonic Tissues)
- Extraembryonic Angioblasts Extraembryonic Capillary Plexus
-
Placenta (Extraembryonic Tissues)
- Primordial Germ Cells Allantois
-
Dermis (Integumentary System)
- Dermal Fibroblasts Dorsal Dermis
-
Fibroblasts
- Dermal Fibroblasts Dorsal Dermis
- Intermediate Mesoderm (Gastrulation Derivatives)
- Lung (Respiratory System)
- Germ Cells (Reproductive System)
- Bone (Muscoskeletal System)
- Cartilage (Muscoskeletal System)
-
Testis (Reproductive System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for CLDN5 Gene
This gene is overexpressed in Adipose - Subcutaneous (x4.1).
This gene is overexpressed in Peripheral blood mononuclear cells (21.6), Platelet (15.6), and Lung (15.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CLDN5 Gene
NURSA nuclear receptor signaling pathways regulating expression of CLDN5 Gene:
CLDN5SOURCE GeneReport for Unigene cluster for CLDN5 Gene:
Hs.505337Evidence on tissue expression from TISSUES for CLDN5 Gene
- Nervous system(4.9)
- Lung(4.6)
- Heart(3.3)
- Blood(2.8)
- Eye(2.1)
- Intestine(2.1)
- Muscle(2.1)
Primer Products
-
OriGene qPCR primer pairs and template standards for CLDN5
-
OriGene qPCR primer pairs for CLDN5
- genomics-online: primer clones - Search results for available CLDN5 gene related products
Gene Expression Assay Products
No data available for Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CLDN5 Gene
Orthologs for CLDN5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | CLDN5 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | CLDN5 33 |
|
||
| cow (Bos Taurus) |
Mammalia | CLDN5 34 33 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Cldn5 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Cldn5 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | CLDN5 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CLDN5 34 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | cldn5 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | cldn5a 34 33 |
|
OneToMany | |
| cldn5b 34 |
|
OneToMany | |||
| cldnk 34 |
|
OneToMany | |||
| FP102191.1 34 |
|
OneToMany |
- Species where no ortholog for CLDN5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for CLDN5 Gene
- ENSEMBL:
- Gene Tree for CLDN5 (if available)
- TreeFam:
- Gene Tree for CLDN5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for CLDN5: view image
Paralogs for CLDN5 Gene
Paralogs for CLDN5 Gene
(18) SIMAP similar genes for CLDN5 Gene using alignment to 2 proteins:
- CLD5_HUMAN
- D3DX19_HUMAN
Variants for CLDN5 Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1001152998 | -- | 19,523,146(-) | C/G | 3_prime_UTR_variant | |
| rs1001412506 | -- | 19,528,532(-) | C/T | upstream_transcript_variant | |
| rs1001730761 | -- | 19,526,481(-) | T/C | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1001851757 | -- | 19,523,168(-) | G/A | 3_prime_UTR_variant | |
| rs1002010191 | -- | 19,527,528(-) | C/T | 5_prime_UTR_variant, genic_upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv4478n100 | CNV | loss | 25217958 |
| esv2751940 | CNV | gain | 17911159 |
| esv3575418 | CNV | gain | 25503493 |
| esv3893434 | CNV | gain | 25118596 |
| nsv588216 | CNV | gain | 21841781 |
| nsv834127 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
66.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
7.81;
83.44% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for CLDN5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- CLDN5
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLDN5 Gene
Disorders for CLDN5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| velocardiofacial syndrome |
|
|
| gray platelet syndrome |
|
|
Search CLDN5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for CLDN5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for CLDN5 Gene
Publications for CLDN5 Gene
- Identification, characterization, and precise mapping of a human gene encoding a novel membrane-spanning protein from the 22q11 region deleted in velo-cardio-facial syndrome. (PMID: 9192844) Sirotkin H … Kucherlapati R (Genomics 1997) 2 3 4 22 58
- Expression pattern of claudins 5 and 7 distinguishes solid-pseudopapillary from pancreatoblastoma, acinar cell and endocrine tumors of the pancreas. (PMID: 19194274) Comper F … Scarpa A (The American journal of surgical pathology 2009) 3 22 58
- Diagnostic utility of expression of claudins in non-small cell lung cancer: different expression profiles in squamous cell carcinomas and adenocarcinomas. (PMID: 19231096) Jung JH … Lee KY (Pathology, research and practice 2009) 3 22 58
- Structure and function of extracellular claudin domains. (PMID: 19538285) Krause G … Müller SL (Annals of the New York Academy of Sciences 2009) 3 22 58
- Claudin-5 overexpression correlates with aggressive behavior in serous ovarian adenocarcinoma. (PMID: 20044634) Turunen M … Santala M (Anticancer research 2009) 3 22 58
Products for CLDN5 Gene
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- VectorBuilder custom plasmid, inducible vectors for CLDN5
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for CLDN5
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Addgene plasmids for CLDN5
- antibodies-online: Search results for 91 available CLDN5 Antibodies ranked by validation data
- Compare Top CLDN5 Antibodies
- Recommended
- 38 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 9 IHC (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 6 IHC Antibodies (anti-mouse)
- 3 IHC (p) Antibodies (anti-mouse)
- 28 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 3 IHC Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- antibodies-online: Search results for 45 available CLDN5 Elisa Kits ranked by validation data
- Compare Top CLDN5 Elisa Kits
- antibodies-online: Search results for 4 available CLDN5 Proteins ranked by validation data
- Compare Top CLDN5 Proteins
- GeneTex CLDN5 Antibody for CLDN5
- Search GeneTex for Proteins for CLDN5
- Santa Cruz Biotechnology (SCBT) Antibodies for CLDN5
- Search Santa Cruz Biotechnology (SCBT) for CLDN5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CLDN5
- Horizon Cell Lines for CLDN5
- genomics-online: cdna clones - Search results for available CLDN5 gene related products
- orf clones - Search results for available CLDN5 gene related products
- genomics-online: gRNA clones - Search results for available CLDN5 gene related products
- genomics-online: primer clones - Search results for available CLDN5 gene related products
- genomics-online: shRNA clones - Search results for available CLDN5 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for CLDN5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for CLDN5
- GeneCopoeia miRNA 3'UTR Target clone products for CLDN5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for CLDN5
Sources for CLDN5 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt